Abstract:Objective To explore the efficacy of minocycline hydrochloride ointment combined with metronidazole in the treatment of severe periodontitis.Methods Eighty-six patients with severe periodontitis treated in the Department of Stomatology of Lianjiang County General Hospital in Fuzhou City from June 2021 to December 2023 were collected and randomly divided into a control group(n=43)and a combination group(n=43)using a random number table method.Both groups received routine treatments such as supragingival scaling and subgingival scaling.The control group was treated with tinidazole,while the combination group was treated with tinidazole combined with minocycline.Compare the improvement of periodontal,gingival saliva microbiota,and gingival crevicular fluid inflammatory factors between two groups before and after treatment.Results After treatment,the gingival bleeding index,probing depth,and plaque index of the combined group were lower than those of the control group(P<0.05).The detection rates of fusobacterium nucleatum,porphyromonas gingivalis,actinobacillus actinomycetes,prevotella intermedia,fusitania flexneri,and dental plaque spirochetes in the saliva of the combined group were lower than those in the control group(P<0.05).The levels of interleukin-1β,interleukin-6,tumor necrosis factor-α,interleukin-8,interleukin-17,and matrix metalloproteinase-8 in the gingival crevicular fluid of the combined group were lower than those in the control group(P<0.05).Conclusion The combination of minocycline hydrochloride ointment and tinidazole in the treatment of severe periodontitis can effectively improve the periodontal health status of patients,reduce salivary microbiota,and alleviate gingival crevicular fluid inflammation.

Abstract:Objective To explore the effect of Self-role identity nursing intervention on patients with schizophrenia in the symptomatic stage.Methods The study period is from January 2024 to December 2024.The research subjects are 70 patients with overt schizophrenia admitted to Shanghang Psychiatric Sanatorium in Longyan and randomly divided into a control group(n=35)and a study group(n=35).The control group received basic nursing intervention,while the study group received self-role identity concept nursing intervention on top of it.The improvement of mental symptoms,quality of life,and compliance between the two groups after intervention was compared.Results After nursing,the scores of the positive and negative symptom scales in the study group were lower than those in the control group(P<0.05).The scores and total scores of each dimension of the inpatient psychosis rehabilitation observe scale in the research group were lower than those in the control group(P<0.05).The scores and total scores of each dimension of the quality of life scale for patients with schizophrenia in the research group were lower than those in the control group(P<0.05).The treatment compliance rate of the research group was higher than that of the control group(P<0.05).Conclusion Self-role identity concept nursing intervention can promote symptom recovery,improve the social function,quality of life and compliance of patients with schizophrenia in the symptomatic stage.

Abstract:Objective To explore the improvement effect of ipsilateral stellate ganglion block(SGB)on intraoperative hemodynamics,postoperative delirium(POD)and pain in elderly patients undergoing thoracoscopic lobectomy.Methods Seventy-eight elderly lung cancer patients who underwent elective thoracoscopic lobectomy at Sanming First Hospital from December 2023 to October 2024 were randomly divided into an observation group(n=39)and a control group(n=39)using a stratified block randomization method.Thirty minutes before anesthesia induction,the observation group accepted SGB(0.3%ropivacaine 5 mL)on the surgical side under ultrasound guidance,while the control group was injected with an equal amount of physiological saline,and the rest of the anesthesia methods were the same.The intraoperative hemodynamic parameters and postoperative scores of visual analog scale(VAS)scores and 3-minute diagnostic confusion assessment method(3D-CAM),as well as POD incidence between two groups were compared.Results Finally,76 patients were included(38 cases in each group).During the operation,the heart rate,mean arterial pressure and oxygen saturation at T2 in the observation group were higher than those in the control group(P<0.05).After surgery,the VAS scores of the observation group were lower than those of the control group at all time points(P<0.05),and the total incidence of POD was lower than that of the control group(P<0.05).Conclusion Ultrasound-guided ipsilateral SGB can stabilize intraoperative hemodynamics,relieve postoperative pain and reduce the incidence of POD in elderly patients undergoing thoracoscopic lobectomy.

Abstract:Objective To explore the effect of five-sense and six-sense intervention combined with pulmonary rehabilitation training in patients after lung cancer surgery.Methods Eighty lung cancer patients admitted to the Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine from June 2023 to June 2024 were selected as the research subjects and randomly divided into a control group(n=40)and an combination group(n=40).The control group received pulmonary rehabilitation training,while the combination group received further combined intervention with five senses and six senses.Compare the improvement of respiratory and motor function,psychological status,self-efficacy,quality of life,and self-care ability between two groups of patients.Results The scores of Borg Scale,21-item depression,anxiety and stress scales,and Medical Research Council dyspnea scale in the combination group were lower than those in the control group(P<0.05).The scores of 6-minute walk test,Chinese version of the strategies used by people to promote health,quality of life questionnaire core 30,and exercise of self-care agency scale in the combination group were higher than those in the control group(P<0.05).Conclusion The five senses and six senses intervention combined with pulmonary rehabilitation training can improve the postoperative respiratory motor function of lung cancer patients,optimize their mood,and enhance self-efficacy and quality of life.

Abstract:Objective To compare the efficacy of plasmakinetic resection of the prostate(PKRP)and transurethral resection of prostate(TURP)in the treatment of benign prostatic hyperplasia(BPH).Methods One hundred and fourteen BPH patients admitted to Xiapu County Hospital from January 2023 to April 2025 were included in the study and randomly divided into a control group and a study group,with 57 patients in each group.The control group was treated with TURP,while the observation group was treated with PKRP.The surgical outcomes and improvements in prostate function,urodynamics,and sexual function were compared between the two groups.Results The observation group had significantly shorter surgical time,intraoperative blood loss,urinary catheter retention time,and hospitalization time compared to the control group(P<0.05).Three months after surgery,the individual scores and total scores of the international prostate symptom score in the observation group were lower than those in the control group(P<0.05).The residual urine volume and urination time of the observation group were lower than those of the control group,while the maximum urine flow rate and average urine flow rate were higher than those of the control group(P<0.05).The core scores and total scores of international index of erectile function-15 in the observation group were higher than those in the control group(P<0.05).Conclusion Compared with TURP,PKRP treatment for benign prostatic hyperplasia has the advantages of shorter surgical time,less bleeding,and faster recovery.It can also significantly improve prostate function and urodynamics in patients,while having a smaller impact on sexual function.

Abstract:Objective To explore the application effect of stepwise nutritional intervention in critically ill patients in the ICU.Methods The subjects were all 126 critically ill patients admitted to the intense care medicine department of Putian University Affiliated Hospital from December 2021 to December 2024.They were divided into two groups based on the different nutritional intervention methods adopted by the patients.In the control group,63 cases received conventional nutritional intervention,while in the observation group,63 cases received stepped nutritional intervention.The serum nutritional indicators,patient generated subjective global assessment(PG-SGA),immune function and complications were compaerd.Results After intervention,the observation group had higher levels of hemoglobin,prealbumin,albumin,transferrin,serum ferritin,and serum iron than the control group(P<0.05).The self-evaluation part,medical staff evaluation part,and total score of PG-SGA patients in the observation group were lower than those in the control group(P<0.05).The observation group had higher levels of CD3+,CD4+,and CD4+/CD8+than the control group,while CD8+was lower than the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion Through the stepwise nutritional intervention program for critically ill patients in the ICU,sufficient nutritional support can be provided for the patients,their nutritional status can be improved,the immune function of the body can be enhanced,and the risk of complications can be reduced.

Abstract:Objective To explore the application effect of prospective nursing in children with severe pneumonia undergoing nebulization inhalation.Methods One hundred and twenty pediatric patients with severe pneumonia treated with nebulized inhalation at Ninghua County General Hospital from June 2021 to September 2024 were selected as the research subjects.They were randomly divided into a control group and an observation group using a random number table method,with a sample size of 60 in each group.The control group received routine nursing care,while the observation group received prospective nursing intervention on the basis of the control group.The clinical symptom relief time,score of Mishel uncertainty in illness scale-family member form(MUIS-FM),and parental satisfaction between two groups of children were compared.Results After nursing,the clinical symptom relief time in the observation group was significantly shorter than that in the control group(P<0.05).The score of MUIS-FM in the observation group was significantly lower than that in the control group(P<0.05).The score of parental satisfaction in the observation group was significantly higher than that in the control group(P<0.05).Conclusion In the treatment of severe pneumonia in children with nebulization inhalation,the use of prospective nursing can significantly improve clinical symptoms,reduce the uncertainty of family members'illness,and improve parental satisfaction,with high clinical application value.

Abstract:Objective To explore the clinical efficacy of pediatric tuina combined with budesonide nebulized inhalation in the treatment of acute asthma attack.Methods One hundred children with acute asthma attacks admitted to the Xinshi Street Community Health Service Center in Baiyun District,Guangzhou from April 2024 to August 2025 were selected as the research subjects,they were randomly divided into a control group and an observation group using a random number table method,with 50 cases in each group.On the basis of basic treatment,the control group was treated with budesonide nebulization inhalation,while the observation group was further treated with pediatric massage.The duration of clinical symptoms and the improvement of inflammatory factors and lung function between two groups of children were compared.Results After treatment,the duration of restlessness,coughing,dyspnea,wheezing,and cyanosis in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).The levels of tumor necrosis factor-α,interleukin-1β,interleukin-6,interleukin-8,interleukin-18,and immunoglobulin E in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The observation group had higher tidal volume,%T-PF,%V-PF,and peak expiratory flow than the control group,while RR was lower than the control group,with statistical significance(P<0.05).Conclusion The combination of pediatric massage and budesonide nebulization therapy for acute asthma attacks can effectively shorten the duration of symptoms,reduce inflammatory reactions,and improve lung function.

Abstract:Objective To explore the application value of scraping therapy combined with traditional Chinese medicine(TCM)emotional nursing in patients with cough following upper respiratory tract infection.Methods A total of 96 patients with cough following upper respiratory tract infection admitted to Jiangsu Hospital of Traditional Chinese Medicine from January 2022 to December 2024 were randomly divided into conventional group and combined group,with 48 cases in each group.The patients in the conventional group received symptomatic treatment according to the doctor's advice and supplemented by routine nursing.Combined group was treated with scraping therapy combined with traditional Chinese emotional care on the basis of conventional group.The curative effects,TCM syndrome scores before and after treatment,sleep quality(Pittsburgh sleep quality index,PSQI),quality of life(the MOS item short from health survey,SF-36),psychological status[(self-rating anxiety scale,SAS)、(self-rating depression scale,SDS)],nursing satisfaction and incidence of complications of the two groups were compared and analyzed.Results Before intervention,there were no significant differences in TCM syndrome score,PSQI,SF-36,SAS and SDS scores between the two groups(P>0.05).After intervention,TCM syndrome score,PSQI,SF-36,SAS and SDS scores were significantly improved between the two groups(P<0.05).After intervention,the TCM syndrome score,PSQI,SF-36,SAS and SDS scores in the combined group were significantly better than those in the conventional group(P<0.05).The total effective rate of combined group and nursing satisfaction were significantly higher than those of conventional group(P<0.05),and no serious adverse reactions occurred in both groups during the intervention.Conclusion The scraping therapy combined with traditional Chinese emotional nursing can significantly improve the efficacy and quality of life,negative emotions,sleep quality,and nursing satisfaction in patients with cough following upper respiratory tract infection,which is worthy of promotion.

Abstract:Objective To explore the changes in lesion unit ablation,ablation time,lesion changes,levels of inflammatory factors,thyroid function and postoperative complications of micropapillary thyroid carcinoma after ultrasound-guided microwave ablation and radiofrequency ablation.Methods According to different treatment methods,75 patients diagnosed with papillary thyroid microcarcinoma in Gutian County Hospital from January 2022 to June 2024 were divided into two groups.Both groups received ultrasound-guided intervention.Among them,37 cases in the observation group underwent microwave ablation,and 38 cases in the control group underwent radiofrequency ablation.Evaluate the differences in changes of indicators such as lesion unit ablation,ablation time,lesion changes,levels of inflammatory factors,thyroid function,and occurrence of complications between the two groups.Results Compared with the control group,the lesion unit ablation and ablation time in the observation group were significantly shorter(P<0.05).Four months after the operation,the lesion volume of both groups decreased significantly,and the volume of the observation group was significantly smaller than that of the control group(P<0.05).At the same time,compared with the observation group,the lesion reduction rate of the control group was significantly lower(P<0.05).Compared with those before the operation,the levels of inflammatory factors in both groups increased one week after the operation,but those in the observation group were significantly lower than those in the control group(P<0.05).Compared with those before the operation,all indexes of thyroid function in the observation group were significantly better than those in the control group one week after the operation(P<0.05).Compared with the control group,the incidence of postoperative complications in the observation group was significantly higher(P<0.05).Conclusion After ultrasound-guided microwave ablation treatment for patients with papillary thyroid microcarcinoma,the ablation of lesion units and ablation time are significantly shortened,and it is less likely to have a significant impact on inflammatory factors and thyroid function.However,the incidence of postoperative complications after ultrasound-guided radiofrequency ablation treatment is relatively lower.

Abstract:Objective To explore the effect of psychological nursing based on motivational interview in patients with hypertension and coronary heart disease.Methods This study selected 45 patients with hypertension and coronary heart disease before the implementation of motivational interview-based psychological nursing mode in 910th Hospital of Joint Logistic Support Force from July 2022 to June 2023 as the conventional group,and 45 patients with hypertension and coronary heart disease after the implementation of motivational interview-based psychological nursing mode in 910th Hospital of Joint Logistic Support Force from July 2023 to June 2024 as the psychological group.The effects of the two groups were compared and analyzed.Results Before intervention,there was no significance in disease knowledge reserve,self-management ability,treatment compliance,psychological status,psychological resilience and quality of life scores between the two groups(P>0.05).After intervention,the above indexes were significantly improved between the two groups,and the psychological group was significantly better than the conventional group(P<0.05).Nursing satisfaction in psychological group was significantly higher than that in conventional group(P<0.05).Conclusion The application of motivational interview based psychological nursing in patients with hypertension and coronary heart disease can significantly improve patients'psychological resilience and treatment compliance,and improve patients'negative emotions and quality of life,which is worthy of promotion.

Abstract:Objective To explore the application effect of detail and psychological dual-track nursing management in patients undergoing gastrointestinal endoscopy.Methods Sixty patients who underwent gastrointestinal endoscopy and received conventional care at the Second Affiliated Hospital of Nanjing Medical University from January to December 2024 were selected as the conventional group.Another sixty patients who received detailed and psychological dual-track nursing management during the same period were selected as the combined nursing group.The examination time,cooperation level,comfort level,nursing satisfaction,as well as physiological stress responses(heart rate,systolic blood pressure,diastolic blood pressure)upon admission and before the examination,along with self-efficacy and negative emotions before and after the intervention,were observed and compared between the two groups.Results The combined nursing group showed significantly higher scores for cooperation and comfort,as well as shorter examination times compared to the conventional group(all P<0.05).Prior to the examination,both groups exhibited significantly elevated heart rate,systolic blood pressure,and diastolic blood pressure levels compared to admission,with the combined nursing group demonstrating significantly lower levels than the conventional group(all P<0.05).After the intervention,both self-efficacy and negative emotion scores improved significantly compared to pre-intervention levels,with the combined nursing group outperforming the conventional group in both aspects(all P<0.05).The nursing satisfaction score of the combined nursing group was significantly higher than that of the conventional group(P<0.05).Conclusion The dual-track nursing management of details and psychology can effectively improve the physiological and psychological stress of patients undergoing gastrointestinal endoscopy,ensuring the smooth progress of the examination,and is worth promoting and using.

Abstract:Objective To explore the effect of predictive risk nursing model based on root cause analysis on psychological stress and nursing risk events in patients undergoing orthopedic surgery.Methods In this study,110 orthopedic surgery patients who received surgical treatment and routine nursing in the operating room in Rudong County People's Hospital from October 2024 to December 2024 were selected as the control group,and 110 orthopedic surgery patients who received surgical treatment and predictive risk nursing based on root cause analysis in the hospital during the same period were selected as the observation group.A comparative analysis was conducted on the psychological stress[(self-rating anxiety scale,SAS)、(self-rating depression scale,SDS)、(stanford acute stress reaction questionnaire,SASRQ)],incidence of nursing risk events,nursing quality and nursing satisfaction of the two groups.Results There were no significant differences in SAS,SDS,and SASRQ scores between the two groups before intervention(P>0.05).After intervention,the SAS,SDS,and SASRQ scores of the two groups were significantly improved(P<0.05),and the SAS,SDS,and SASRQ scores of the observation group were significantly lower than those of the control group(P<0.05).The incidence of nursing risk events in the observation group was significantly lower than that in the control group(P<0.05),and the quality of nursing and nursing satisfaction were significantly higher than those in the control group(P<0.05).Conclusion The application of predictive risk nursing model based on root cause analysis in the operating room nursing for patients with orthopedic surgery can significantly reduce the psychological stress of patients,and effectively prevent the occurrence of nursing risk events,which meets the nursing needs of operating room and is worthy of promotion.

Abstract:Objective To explore the application value of empathic nursing model in vaginal trial labor among primiparas.Methods A total of 100 primiparas who plan to undergo vaginal trial labor at Sheyang Maternal and Child Health Care Hospital from March 2023 to April 2024 were selected and randomly divided into the routine group and the empathic group,with 50 cases in each group.Routine nursing was adopted in the routine group,and empathy nursing was adopted in the empathic group.The nursing effects of the two groups were compared and analyzed.Results After intervention,the fear of childbirth,negative emotions,and quality of life scores in both groups improved significantly compared to before intervention,and the empathy group had significantly better scores than the routine group after intervention(all P<0.05).The total labor process of the empathic group was significantly shorter than that of the routine group,the cesarean section rate was significantly lower than that of the routine group,and the rate of exclusive breastfeeding after 42 days postpartum was significantly higher than that of the routine group(all P<0.05).There was no significant difference in Apgar scores between the two groups of newborns(P>0.05).Conclusion Empathic nursing can significantly reduce the mental stress,negative emotion and delivery fear of primipara,and enhance the confidence of vaginal delivery.

Abstract:Objective To exploring the application effect of comprehensive nursing incorporating IKAP theory in patients undergoing percutaneous renal biopsy(PRB).Methods A total of 160 patients who underwent PRB at the Affiliated Hospital of Guizhou Medical University from January to December 2023 were selected as the study subjects.All patients were randomly divided into an IKAP group and a control group using a random number table method,with 80 patients in each group.The IKAP group received comprehensive nursing incorporating IKAP theory,while the control group received routine nursing.The anxiety and depression levels before and after nursing care between two groups,as well as the degree of pain and incidence of postoperative complications at different time points after surgery were compared.Results After nursing,the anxiety and depression scores of both groups were significantly lower than before nursing,and the anxiety and depression scores of the IKAP group were significantly lower than those of the control group after nursing(P<0.05).There was no significant difference in pain scores between the two groups at 6 hours after surgery(P>0.05).At 12 and 24 hours after surgery,the pain score in the IKAP group was significantly lower than that in the control group(P<0.05).The total incidence of postoperative complications in the IKAP group was significantly lower than that in the control group(P<0.05).Conclusion Among patients undergoing PRB,adopting comprehensive nursing integrated with IKAP theory can improve patients'anxiety and depression,alleviate pain levels,and have fewer postoperative complications.It is worth promoting and using.

Abstract:Objective To investigate the value of 24-hour ambulatory blood pressure monitoring in the differential diagnosis of masked hypertension(MH).Methods A total of 1,102 high-risk individuals with cardiovascular disease who were treated at the Chentangzhuang Street Community Health Service Center in Hexi District,Tianjin from November 2021 to November 2024 were selected as the research subjects.All individuals underwent clinic blood pressure measurement and 24-hour dynamic blood pressure monitoring.Analyze the diagnosis of hypertension in this population and the differences in blood pressure between different populations.Results Among the 1,102 subjects,538 had normal blood pressure,413 had true hypertension,31 had white coat hypertension,and 120 had masked hypertension.The detection rate of true hypertension and masked hypertension by 24-hour dynamic blood pressure monitoring is significantly higher than that of blood measurement in clinic(P<0.05).The systolic blood pressure in individuals with normal blood pressure and masked hypertension is significantly lower than that of individuals with true hypertension and white coat hypertension(P<0.05).The 24-hour dynamic monitoring blood pressure in individuals with normal blood pressure and white coat hypertension was significantly lower than that of individuals with true hypertension and masked hypertension(P<0.05).Conclusion The 24-hour dynamic blood pressure monitoring can effectively reduce the risk of missed diagnosis of masked hypertension,and also prevent its misdiagnosis as white coat hypertension.

Abstract:Objective To explore the application effect of knowledge-attitude-practice(KAP)health education model combined with psychological nursing in patients with chronic gastritis.Methods A total of 242 patients with chronic gastritis admitted to the Zhangzhou Second Hospital of Traditional Chinese Medicine from August 2022 to July 2024 were selected as the study subjects and randomly divided into a control group(routine nursing)and a combined group(KAP health education model combined with psychological nursing),with 121 cases in each group.The disease KAP levels,self-efficacy,negative emotions,quality of life,and sleep conditions were compared and analyzed before and after the intervention in both groups.Results After the intervention,the levels of disease KAP,self-efficacy,negative emotions,quality of life,and sleep status scores in both groups significantly improved compared to before the intervention.Moreover,the combined group's scores on these indicators were significantly superior to those of the control group(all P<0.05).Conclusion For patients with chronic gastritis,adopting the KAP health education model combined with psychological care can effectively alleviate negative emotions,improve quality of life and sleep conditions,and enhance disease-related knowledge and self-efficacy,making it a worthwhile approach for widespread implementation.

Abstract:Objective To explore the application effect of embedding beans in auricular points combined with traditional Chinese medicine(TCM)characteristic nursing in patients with diabetes mellitus complicated with insomnia.Methods In this study,96 patients with diabetes mellitus combined with insomnia who were treated in Wuqing District Hospital of Traditional Chinese Medicine of Tianjin from January 2021 to March 2024 were selected as research objects and randomly divided into traditional group and TCM characteristic group,with 48 cases in each group.The traditional group was treated with traditional nursing,and the TCM characteristic group was treated with ear point embedding beans combined with TCM characteristic nursing.The effects of the two groups were compared and analyzed.Results Before the intervention,there were no significant differences in fasting plasma glucose(FPG),2-hour postprandial blood glucose(2hPG),sleep quality(pittsburgh sleep quality index,PSQI),self-management ability,and quality of life(the 36-item short form health survey,SF-36)between the two groups(P>0.05).After the intervention,FPG,2hPG,PSQI,self-management ability,and SF-36 in both groups were significantly improved(P<0.05).Moreover,after the intervention,the FPG,2hPG,PSQI,self-management ability and SF-36 in the TCM characteristic group were significantly better than those in the traditional group(P<0.05).The nursing satisfaction of patients in the TCM characteristic group was significantly higher than that in the traditional group(P<0.05).Conclusion Auricular point embedding combined with TCM characteristic nursing for patients with diabetes complicated with insomnia can significantly improve their blood glucose levels and sleep quality,enhance their self-management ability and quality of life,and increase nursing satisfaction.

Abstract:Objective To explore the clinical efficacy of medical composite chitosan-cellulose dressings in the treatment of superficial second-degree skin injuries.Methods A total of 192 patients with superficial second-degree skin injuries who were treated at the Foot and Ankle Surgery Department of Shenyang Orthopedic Hospital between January 2024 and April 2025 were selected and randomly divided into a control group,observation group 1,and observation group 2,with 64 cases in each group.The control group received traditional sterile gauze dressing treatment,observation group 1 was treated with chitosan medical biological wound repair dressing,and observation group 2 was treated with medical chitosan wound protective film.The wound healing time,pain levels during dressing changes,and bacterial culture positive rates,wound area,and inflammatory indicators at different time points after treatment were compared among the three groups.Additionally,the scar formation status was compared among the three groups four weeks after wound healing.Results The wound healing time of observation group 1 was(7.5±1.7)days,and observation group 2 was(7.6±1.6)days,both significantly shorter than the control group's(9.3±1.9)days(P<0.05).There was no significant difference in wound healing time between observation group 1 and observation group 2(P>0.05).The pain score during dressing change in observation group 1 was(1.9±0.7)points,while observation group 2 was(2.0±0.8)points,both significantly lower than the control group's(2.6±1.0)points(P<0.05).There was no significant difference in pain scores between observation group 1 and observation group 2 during dressing changes(P>0.05).The positive rates of wound bacterial culture on the 3rd and 7th day of treatment in observation group 1 and observation group 2 were significantly lower than those in the control group(P<0.05).There was no significant difference in the positive rate of wound bacterial culture between observation group 1 and observation group 2 on the 3rd and 7th day of treatment(P>0.05).The wound area of observation group 1 and observation group 2 on the 3rd and 7th day of treatment,as well as during healing,were all significantly smaller than those of the control group(P<0.05).There was no significant difference in the wound area between observation group 1 and observation group 2 on the 3rd and 7th day of treatment and at the time of healing(P>0.05).The levels of inflammatory markers in observation group 1 and observation group 2 were significantly lower than those in the control group on the 3rd and 7th day of treatment(P<0.05).There was no significant difference in the levels of inflammatory markers between observation group 1 and observation group 2 on the 3rd and 7th day of treatment(P>0.05).After 4 weeks of wound healing,the scar scores of observation group 1 were(3.8±1.7)points and observation group 2 were(4.2±1.5)points,both significantly lower than the control group's(5.2±1.5)points(P<0.05).There was no significant difference in scar scores between observation group 1 and observation group 2 after 4 weeks of wound healing(P>0.05).Conclusion The use of composite chitosan cellulose dressings for the treatment of superficial second degree skin injuries has shown good results,promoting wound healing,reducing pain during dressing changes,effectively controlling wound infections,inhibiting inflammatory reactions,and reducing scar formation.It is worthy of clinical promotion and application.

Abstract:Objective To explore the therapeutic effect of Huazhuo Jiangzhi Decoction on patients with mixed hyperlipidemia.Methods The study subjects were all selected from the outpatient department of Cardiovascular Medicine at the First Affiliated Hospital of Guizhou University of Chinese Medicine.Sixty patients from June 2023 to August 2024 with mixed hyperlipidemia were enrolled as study subjects.The enrolled patients were divided into a control group and an observation group,with 30 patients in each group by random number table method.The control group received conventional western medicine treatment,while the observation group was treated with modified Huazhuo Jiangzhi Decoction.The traditional Chinese medicine symptom scores and improvement in blood lipids,and their effects on liver and kidney function were further compared between the two groups.Results After treatment,the observation group had significantly lower scores for traditional Chinese medicine symptoms such as obesity,limb fatigue,and abdominal distension compared to the control group(P<0.05).The body mass index,waist circumference,and hip circumference of the observation group were also significantly lower than those of the control group(P<0.05).The observation group had significantly lower levels of total cholesterol,triglyceride,and low-density lipoprotein,while high-density lipoprotein were higher than those of the control group(P<0.05).There were no significant differences in alanine aminotransferase,aspartate aminotransferase,creatinine,and blood urea nitrogen levels between the two groups(P>0.05).Conclusion For patients with mixed hyperlipidemia,Huazhuo Jiangzhi Decoction can effectively alleviate clinical symptoms and obesity,improve lipid metabolism,and has good safety.