Abstract:Objective To explore the effect of Shengti moxibustion combined with massage and electrical stimulation in the treatment of postpartum pelvic floor dysfunction.Methods A total of 86 postpartum women with pelvic floor dysfunction treated at Dongping County People's Hospital from March 2022 to March 2024 were selected as the subjects.All patients were divided into a control group and an observation group(43 cases in each group)using a random number table method.The control group received conventional education and electrical stimulation therapy.The observation group was treated with meridian massage and Shengti moxibustion on the basis of the control group treatment plan.Compare the clinical treatment effects and pelvic floor muscle strength after treatment between two groups,as well as the pelvic floor surface electromyography values and quantitative staging of pelvic organ prolapse before and after treatment between two groups.Results The effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the proportion of cases with pelvic floor muscle strength levels 4 and 5 in the observation group was significantly higher than that in the control group(P<0.05).The pelvic floor surface electromyography values of the observation group were significantly better than those of the control group after treatment(P<0.05).After treatment,the proportion of cases with grade 0 in the quantitative staging of pelvic organ prolapse in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Adopted treatment with Shengti moxibustion combined with massage and electrical stimulation has good clinical effects for postpartum women with pelvic floor dysfunction,which can enhance pelvic floor muscle strength,improve pelvic organ prolapse,and improve pelvic floor function.It is worth promoting and using.

Abstract:Objective To explore the effect of moxifloxacin combined with carbocisteine in the treatment of community-acquired pneumonia(CAP).Methods A total of 150 patients with CAP who were treated in Changshu First People's Hospital from June 2021 to June 2024 were selected.All the patients were divided into a moxifloxacin group and a control group with 75 cases in each by different treatment plans.The moxifloxacin group was treated with moxifloxacin combined with carbocisteine,while the control group was treated with piperacillin sodium and tazobactam sodium combined with carbocisteine.The treatment effects,symptom disappearance time,severity of pneumonia and levels of inflammatory factors before and after treatment were compared between the two groups.Results The total effective rate of moxifloxacin group was significantly higher than that of control group(P<0.05).The recovery time of body temperature,disappearance of cough and sputum,normalization of blood routine,and disappearance of lung rales in the moxifloxacin group were significantly shorter than those in the control group(all P<0.05).Before treatment,there was no significant difference in the scores of pneumonia severity index(PSI),the levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and procalcitonin(PCT)between the two groups(P>0.05).After treatment,the scores of PSI and the levels of CRP,TNF-α,IL-6,and PCT in both groups were lower than before treatment,and the levels of these indicators in the moxifloxacin group were significantly lower than those in the control group after treatment(all P<0.05).Conclusion For patients with CAP,treatment with moxifloxacin combined with carbocisteine on the basis of symptomatic treatment has a good therapeutic effects,can promote patient recovery,and is worthy of clinical promotion and use.

Abstract:Objective Analyze the disease composition and trends of inpatients in the otolaryngology department of a large tertiary hospital in eastern Inner Mongolia Autonomous Region over the past decade.Methods The clinical data of inpatients in the otolaryngology department of a large tertiary hospital in eastern Inner Mongolia Autonomous Region from June 1st,2013 to May 31st,2022 were collected in an anonymized manner.Based on the main diagnosis,according to the 10th edition of the International Statistical Classification of Diseases and Related Health Problems(ICD-10),the medical records were standardized and organized by using Excel 2022 software.Stratified by hospitalization years,age,gender,and ethnicity,the epidemiological descriptive analysis on the composition and changes of the top ten ear,nose,and throat diseases were analyzed using SPSS 26.0 software.Results A total of 17,367 patients'clinical data were collected,among which the top ten diseases in terms of patient numbers were chronic tonsillitis(19.39%),sudden idiopathic hearing loss(8.84%),sinusitis(8.45%),nasal septum deviation(7.45%),adenoid hypertrophy(7.39%),vocal cord polyps(5.55%),nasal bone fractures(3.82%),nasal polyps(3.56%),preauricular fistula(2.24%),and sleep apnea(2.20%).The disease spectrum has changed over the past decade,but the overall disease structure is relatively stable,with the number of patients with chronic tonsillitis basically ranking first in the disease spectrum over the years.The average age of patients is(32.44±22.59)years old,with the highest proportion of patients aged≤18 years old being the largest.The prevalence of otorhinolaryngological diseases varied among different age groups.The number of male patients(61.18%)is higher than that of females(38.82%),and chronic tonsillitis ranked first in the case number among both genders.The Mongolian ethnic group accounts for 20.95%,the Han ethnic group accounts for 74.30%,and other ethnic groups account for 4.74%.The order of diseases varies among different ethnic groups,with chronic tonsillitis ranking first.Conclusion Chronic tonsillitis is the main type of disease among hospitalized patients in the otolaryngology department of the hospital,and should be given special attention.Corresponding prevention and treatment measures should be taken,with a focus on protecting adolescent patients aged≤18 years old.Meanwhile,in conjunction with the disease spectrum,effective preventive and health care activities in otolaryngological disease should be implemented,and health medical resources should be allocated rationally.

Abstract:Objective To explore the clinical effects of ear scraping therapy for chronic insomnia based on polysomnography(PSG)technology.Methods A total of 100 patients with chronic insomnia who were treated at Weifang Hospital of Traditional Chinese Medicine from April 2022 to April 2024 were included as research objects.They were randomly divided into a control group and a study group with 50 patients in each group.The control group received conventional medication treatment,while the study group received ear scraping therapy on the basis of the control group treatment.Both groups were continuously treated for 10 days,and the sleep status of the two groups was monitored by PSG before and after treatment.The subjective sleep experience(Pittsburgh sleep quality index),quality of life,polysomnography results and treatment satisfaction of the patients in both groups before and after treatment were compared.Results After treatment,the Pittsburgh sleep quality index score of the study group was significantly lower than that of the control group,and the quality of life score was significantly higher than that of the control group(all P<0.05).After treatment,the PSG indicators in the study group were significantly better than those in the control group(all P<0.05).The overall treatment satisfaction in the study group was significantly higher than that in the control group(P<0.05).Conclusion On the basis of conventional medication treatment,chronic insomnia patients using ear scraping therapy based on PSG technology can have enhanced subjective sleep experience,prolonged sleep time,improved sleep quality and quality of life.It is worth promoting and using.

Abstract:Objective To explore the effect of individualized nursing with psychological nursing as the core in patients undergoing coronary artery stent implantation surgery.Methods A total of 194 patients who underwent coronary artery stent implantation surgery at the 910th Hospital of the Joint Logistics Support Force from June 2023 to June 2024 were selected as the study subjects.All the patients were randomly divided into a routine group and a psychological group,with 97 patients in each group.The routine group received routine nursing,while the psychological group received individualized nursing with psychological nursing as the core.The occurrence of complications,adverse events,and nursing satisfaction were observed and compared between the two grups,as well as negative emotions,psychological resilience,treatment compliance,and quality of life before and after nursing.Results After nursing,the negative emotions,psychological resilience,treatment compliance,and quality of life scores of both groups improved compared to before nursing,and the scores of the psychological group were significantly better than those of the routine group(P<0.05).The incidence of complications in the psychological group was significantly lower than that in the control group(P<0.05),and the nursing satisfaction was significantly higher than that in the control group(P<0.05).There was no significant difference in the incidence of adverse events between the two groups(P>0.05).Conclusion For patients undergoing coronary artery stent implantation surgery,adopting individualized nursing model with psychological care as the core can enhance their psychological resilience,improve negative emotions,enhance treatment compliance and quality of life,and is worth promoting and using.

Abstract:Objective To study the effects of intervention model guided by timing theory in elderly patients with chronic heart failure.Methods A total of 104 elderly patients with chronic heart failure treated in Guangqian Hospital of Quanzhou from November 2022 to December 2023 were enrolled in this study.They were divided into a control group and a study group,with 52 cases in each group according to the random number table method.The control group adopted conventional intervention,while the study group adopted an intervention model guided by the theory of opportunity based on the conventional intervention.The changes of cardiac function,self-care ability and quality of life before and after intervention were compared between the two groups.Results After six months of intervention,the cardiac output and left ventricular ejection fraction in the study group were higher than those in the control group,while the left ventricular end-systolic diameter and left ventricular end-diastolic diameter were lower than those in the control group(P<0.05).The scores of the exercise of self-care agency scale in the study group were higher than those in the control group(P<0.05).The scores and total score of the Minnesota heart failure quality of life questionnaire in the study group were lower than those in the control group(P<0.05).Conclusion The intervention model guided by timing theory in elderly patients with chronic heart failure can effectively promote the improvement of cardiac function,self-care ability and quality of life of patients.

Abstract:Objective To evaluate the early analgesic effect of dexmedetomidine combined with ropivacaine under ultrasound guidance after cesarean section.Methods Sixty parturients undergoing cesarean section surgery,admitted to the First Affiliated Hospital of Jinzhou Medical University from August 2024 to February 2025,were selected and randomly divided into an observation group and a control group,with 30 cases in each group.The control group was given 30 mL of 0.3%ropivacaine for bilateral transversus abdominis plane(TAP)block analgesia,while the observation group was given 1 μg/kg of dexmedetomidine combined with 30 mL of 0.3%ropivacaine for bilateral TAP block analgesia.The pain conditions,hemodynamic indicators,postoperative QoR-15 scale scores and the occurrence of adverse reactions within 2 days after surgery were compared between the two groups at 1 hour(T1),12 hours(T2),24 hours(T3),and 48 hours(T4)after surgery.Results There was no statistically significant difference in the visual analogue scale(VAS)scores of T1 and T4 between the observation group and the control group after the operation(P>0.05),while the VAS scores of T2 and T3 after the operation were lower than those of the control group(P<0.05).There was no statistically significant difference in hemodynamic indicators and the incidence of adverse reactions between the two groups at each time point(P>0.05).The QoR-15 scale scores of the observation group at T3 and T4 time points after the operation were higher than those of the control group(P<0.05).Conclusion The analgesic regimen of ultrasound-guided dexmedetomidine combined with ropivacaine transversus abdominis plane block after cesarean section can effectively prolong the postoperative analgesic time without increasing the occurrence of adverse reactions,and has a good pain management effect.

Abstract:Objective To explore the impact of a health-promotion model based on internal perception management on the prognosis of chronic heart failure patients.Methods From December 2022 to December 2023,two hundred and four patients with chronic heart failure admitted to Pinghe County Hospital of Zhangzhou were selected and randomly divided into a control group and a study group,with one hundred and two patients in each group.Four patients in the control group were lost to follow-up,and three patients in the study group were lost to follow-up,so there were ninety-eight patients in the control group and ninety-nine patients in the study group.The control group received conventional nursing care,while the study group received a health promotion model based on internal perception ability management.The health promotion behaviors,self-care ability,health literacy,cardiopulmonary function,and cardiac function classification of the two groups of patients were compared.Results At discharge and twelve months after discharge,the scores of health-promoting behaviors,self-care ability,and health literacy in the study group were higher than those in the control group(P<0.05).Twelve months after discharge,the study group had significantly higher values in metabolic equivalents,peak oxygen uptake and equivalent for carbon dioxide slope,and lower cardiac function classification compared to the control group(P<0.05).Conclusion The health promotion model based on intrinsic perception ability management has a certain improvement effect on the health-promoting behaviors,self-care ability,and health literacy of patients with chronic heart failure,and can also promote the recovery of cardiopulmonary function.

Abstract:Objective To explore the influencing factors of postoperative clinical prognosis in patients with traumatic fractures of the lower extremities.Methods A retrospective collection of 360 patients with traumatic fractures of the lower extremities admitted to Liaocheng Second People's Hospital from January 2018 to December 2024 was conducted.These patients were divided into a poor prognosis group(n=60)and a good prognosis group(n=300)based on their prognosis.The clinical data of the two groups were compared to explore factors that may lead to poor patient prognosis.Results Multivariate logistic regression analysis revealed that age(OR=2.461),hyperlipidemia(OR=2.750),diabetes(OR=2.227),preoperative acute complications(OR=2.406),prognostic nutritional index(OR=1.359),N-terminal pro-brain natriuretic peptide(OR=1.015),monocyte chemoattractant protein-1(OR=1.115),and C-reactive protein(OR=4.189)were factors influencing poor postoperative clinical prognosis in patients with lower limb traumatic fractures(P<0.05).Conclusion Age,hyperlipidemia,diabetes,prognostic nutritional index,preoperative acute complications,monocyte chemoattractant protein-1,N-terminal pro-brain natriuretic peptide,and C-reactive protein are closely related to the postoperative clinical prognosis of patients with lower limb traumatic fractures.For patients with the aforementioned risk factors,the risk of poor prognosis should be vigilantly monitored.

Abstract:Objective To study the clinical value of xipayi gum-fixing liquid combined with minocycline in the treatment of periodontitis of Stage Ⅲ.Methods The 82 patients with periodontitis of Stage Ⅲ who were treated in Linzi Maternal and Child Health Hospital(Qidu Hospital)from June 2021 to March 2024 were included in the study.They were divided into two groups according to the random number table method.The control group(41 cases)was treated with minocycline,and the study group(41 cases)was treated with sipayi gum-fixing solution on the basis of minocycline.The clinical efficacy,periodontal index,inflammation index,bone absorption index and adverse reactions were compared between the two groups.Results The total clinical efficacy rate of the study group was 97.56%,which was higher than 80.49%of the control group(P<0.05).The gingival index,periodontal pocket depth,sulcular bleeding index,and mobility in the study group were all lower than those in the control group(P<0.05).The levels of interleukin-6,interleukin-8,interleukin-1β,interleukin-17,tumor necrosis factor-α,and C-reactive protein in the study group were all lower than those in the control group(P<0.05).The bone resorption in the study group was lower than those in the control group(P<0.05).The incidence of adverse reactions in the study group was 9.76%,which was not statistically significantly different from the 4.88%in the control group(P>0.05).Conclusion Sipayi Gum-Fixing Liquid combined with Minocycline has a significant therapeutic effect,which can effectively improve the periodontal health of patients with periodontitis of Stage Ⅲ,inhibit inflammatory reaction and bone absorption,and has no significant increase in adverse reactions.

Abstract:Objective To study the clinical value of intervention model based on self-regulation theory in elderly patients with ischemic stroke(IS).Methods A total of 92 elderly IS patients treated in Nanping First Hospital Affiliated to Fujian Medical University from July 2021 to September 2023 were enrolled in this study.They were divided into a control group and a study group,with 46 cases in each group according to the random number table method.The control group received the conventional intervention mode,while the study group received the intervention mode based on self-regulation theory.The scores of self-care ability[self-care ability scale for the elderly(SASE)],health promoting lifestyle Ⅱ[health promoting lifestyle profile-Ⅱ(HPLP-Ⅱ)]and compliance were compared between the two groups.Results After 12 weeks of intervention,the scores of SASE and HPLP-Ⅱ in the study group were higher than those in the control group(P<0.05).The compliance of the study group was higher than that of the control group(P<0.05).Conclusion The intervention model based on self-regulation theory can effectively improve the self-care ability and compliance,and promote the formation of a healthy lifestyle in elderly IS patients.

Abstract:Objective To analyze the role of cement-injected pedicle screw internal fixation in osteoporosis with lumbar degenerative diseases.Methods From August 2022 to August 2024,90 patients with osteoporosis accompanied by lumbar degenerative diseases admitted to Tianjin Hospital in Ningqiang County were selected and divided into a control group and an observation group,with 45 patients in each group,based on surgical methods.The control group underwent conventional pedicle screw internal fixation,while the observation group underwent bone cement-enhanced pedicle screw internal fixation.The postoperative radiographic indicators,lumbar function,and complication rates were compared between the two groups.Results The postoperative Cobb angle,scores of Oswestry functional impairment index,Roland-Morris functional impairment survey,and Quebec low back pain disorder scale of the observation group were lower than those of the control group,while the height of adjacent intervertebral spaces,bone density T values,vertebral CT values,and Japanese Orthopaedic Association Evaluation of Treatment scores were higher than those of the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion Cement-injected pedicle screw internal fixation can improve the lumbar structure and function in patients with osteoporosis and lumbar degenerative diseases,and also plays a role in preventing complications.

Abstract:Objective To evaluate the effectiveness of a problem-based intervention model in elderly patients with early-stage Parkinson's disease.Methods A total of 94 elderly patients with early Parkinson's disease(PD)treated in Nanping First Affiliated Hospital of Fujian Medical University from August 2021 to August 2023 were enrolled in this study,and divided into a control group and a study group,with 47 cases in each group according to the random number table method.The control group received standard interventions,while the study group was treated with a problem-focused intervention approach.The scores of neurological function[mini mental state examination(MMSE),Montreal cognitive assessment(montreal cognitive),Parkinson's disease sleep scale(PDSS)],self-care ability[exercise of self-care ability agency(ESCA)]and quality of life[Parkinson's disease quality of life questionnaire 39(PDQ-39)]was compared between the two groups.Results After 3 months of intervention,the MMSE,MoCA,PDSS and ESCA scores of the study group were higher than those of the control group,while the PDQ-39 score of the study group was lower than that of the control group(P<0.05).Conclusion The problem-based intervention model effectively improves neurocognitive function,enhances self-care capacity,and promotes quality of life in elderly patients with early-stage PD.

Abstract:Objective To explore the clinical effect of Huoxue Xiaozheng Decoction combined with goserelin in recovery and recurrence in patients after myomectomy.Methods Sixty patients undergoing uterine myomectomy at Xiang'an District Maternal and Child Health Hospital between January 2018 and December 2021 were randomly divided into a control group and an observation group,with 30 patients in each group.Both groups accepted uterine myomectomy.After operation,the control group received goserelin,while the observation group received Huoxue Xiaozheng Decoction combined with goserelin.The improvement in traditional Chinese medicine syndrome scores,sex hormone levels,uterine volume,recurrence rate,and adverse reaction rate were compared between the two groups.Results After treatment,both groups showed reduced symptom scores and levels of luteinizing hormone,follicle-stimulating hormone,and estradiol,and the observation group had lower sex hormone levels than the control group(P<0.05).Both groups showed an increase in uterine volume,while the observation group had smaller uterine volumes after 12 months and 24 months of treatment compared to the control group(P<0.05).The observation group also had a lower recurrence rate of fibroids after 24 months of treatment compared to the control group(P<0.05).Conclusion Patients undergoing myomectomy treated with Huoxue Xiaozheng Decoction combined with goserelin can effectively improve clinical symptoms,reduce sex hormone levels,decrease uterine volume,and effectively prevent postoperative recurrence.

Abstract:Objective To explore the related risk factors of spontaneous abortion in pregnancy with hypothyroidism.Methods Forty cases of natural miscarriage patients with pregnancy complicated by hypothyroidism admitted to Zibo Maternal and Child Health Care Hospital from December 2021 to December 2023 were selected as the observation group.According to a 1:1 ratio,another 40 cases of normal delivery patients with pregnancy complicated by hypothyroidism admitted to our hospital during the same period were selected as the control group.A univariate analysis was conducted on two sets of clinical data,and logistic regression analysis was used to investigate the factors associated with spontaneous abortion.Results There were statistically significant differences in the levels of thyroid stimulating hormone(TSH),homocysteine(Hcy),and the positive rate of thyroid peroxidase antibody(TPOAb)between the two groups(P<0.05).Multivariate logistic regression analysis revealed that TPOAb positivity(OR=3.133),TSH levels≥4.15 mIU/L(OR=3.710),and Hcy levels≥9.54 μmol/L(OR=3.518)were risk factors for spontaneous abortion in pregnant women with hypothyroidism(P<0.05).Conclusion The occurrence of spontaneous abortion in patients with pregnancy complicated by hypothyroidism is correlated with high levels of TSH,high levels of Hcy,and positive TPOAb.Clinically,these factors can be combined to conduct targeted regular screenings for relevant populations and develop relevant prevention and control measures to reduce the incidence of spontaneous abortion.

Abstract:Objective To analyze the effect of high-dose vitamin C assisted azithromycin in the treatment of children with mycoplasma pneumonia.Methods One hundred and forty-seven children with mycoplasma pneumoniae pneumonia admitted to Zhenghe County Hospital of Nanping from January 2023 to December 2024 were randomly divided into a control group of 73 cases and an observation group of 74 cases by random number table method.The control group received sequential therapy with azithromycin,while the observation group received treatment with vitamin C additionally.The clinical effects of the two groups were compared.Results After treatment,the duration of various clinical symptoms and signs in the observation group was shorter than that in the control group(P<0.05).The levels of interleukin-6,procalcitonin,interleukin-17,and high sensitivity C-reactive protein in the observation group were lower than those in the control group(P<0.05).The levels of CD3+and CD4+in the observation group were higher than those in the control group(P<0.05),while there was no statistically significant difference in CD8+levels between the two groups(P>0.05).Conclusion High-dose vitamin C,when used as an adjunct to azithromycin in the treatment of children with mycoplasmal pneumonia,can help expedite symptom relief,reduce inflammatory response,and modulate immune function.

Abstract:Objective To study the effect of pirfenidone capsule combined with glucocorticoid on pulmonary function and pulmonary fibrosis in patients with idiopathic pulmonary fibrosis(IPF).Methods The clinical data of 85 patients with idiopathic pulmonary interstitial fibrosis who were treated in Wuping County Hospital,Wuping from May 2021 to February 2024 were retrospectively analyzed.According to the treatment plan,43 patients in the control group were treated with glucocorticoid,and 42 patients in the observation group were treated with pirfenidone capsules on the basis of glucocorticoid.The clinical efficacy,pulmonary function,pulmonary fibrosis and drug safety were compared between the two groups.Results The total clinical efficacy rate in the observation group was 95.24%,which was higher than 79.07%in the control group(P<0.05).After treatment,the forced expiratory volume in 1 second,peak expiratory flow rate,forced vital capacity and diffusion capacity of the lung for carbon monoxidein the observation group were all higher than those in the control group(P<0.05).The levels of type Ⅲ procollagen,laminin,and type Ⅳ collagen in the observation group were all lower than those in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Pifenidone capsule combined with glucocorticoid has obvious therapeutic effect,which can effectively inhibit pulmonary fibrosis in IPF patients,promote the improvement of pulmonary function,and has good medication safety.

Abstract:Objective To analyze the efficacy of proximal femoral anti-rotation intramedullary nailing in treating intertrochanteric fractures of the femur in elderly patients under different body positions.Methods From January 2022 to January 2024,120 elderly patients with intertrochanteric fractures of the femur treated with proximal femoral anti-rotation intramedullary nails at DongTai BeiHai Orthopedic Hospital were selected as the study subjects.They were randomly divided into an observation group and a control group,with 60 patients in each group.The surgical position for the control group was a supine position with a traction bed,while the surgical position for the observation group was a lateral position without a traction bed.The surgical-related indicators of the two groups were compared,and the hip joint function,fracture reduction quality,and complication occurrence were also compared between the two groups before surgery and six months after surgery.Results After comparative analysis,the surgical time,incision length,fluoroscopy frequency,positioning time,and bleeding volume during the surgery in the observation group were significantly lower than those in the control group(P<0.05).There were no statistically significant differences in Harris hip score,excellent and good rate of fracture reduction,and incidence of complications between the two groups(P>0.05).Conclusion In the treatment of elderly intertrochanteric fractures of the femur with proximal femoral anti-rotation intramedullary nailing,the use of lateral position without traction can effectively expedite the surgical process and reduce intraoperative injuries.However,compared with supine position with traction,the effects of both on hip joint function,fracture reduction,and complications are relatively similar.

Abstract:Objective To explore and analyze the application effect of problem oriented nursing mode in patients with acute lymphoblastic leukemia(ALL).Methods Ninety ALL patients who received treatment in Tianjin First Central Hospital from January 2022 to December 2024 were selected and randomly divided into an observation group and a control group,with 45 cases in each group.The control group received routine nursing care,while the observation group received problem oriented nursing care.The scores of Herth hope index(HHI),Connor-Davidson resilience scale(CD-RISC),functional assessment of cancer therapy-general(FACT-G),and incidence of complications were compared between the two groups.Results After intervention,the scores of each dimension of the HHI,CD-RISC,and FACT-G in both groups showed an upward trend,and the scores in the observation group were higher than those in the control group(P<0.05).The incidence of adverse reactions in the observation group was 4.44%,while that in the control group was 20.00%(P<0.05).Conclusion The problem-oriented nursing model during chemotherapy for patients with ALL can help enhance their hope level and psychological resilience,significantly improve their quality of life,and reduce the occurrence of incidence of adverse.

Abstract:Objective To observe the regulatory effects of jiangzhi tongluo soft capsules on blood lipids,blood viscosity,and endothelial function in patients with hyperlipidemia of qi stagnation and blood stasis type.Methods One-hundred patients with hyperlipidemia of qi stagnation and blood stasis type admitted to Qinzhou District Shimaping Street Community Health Service Center of Tianshui from January 2022 to December 2024 were randomly divided into a control group and a study group,with 50 patients in each group.The control group was treated with atorvastatin combined with ezetimibe,while the study group was treated with jiangzhi tongluo soft capsules additionally.The improvement of blood lipids,viscosity,and endothelial function between two groups after 2 months of treatment were compaerd.Results After treatment,the total cholesterol,triglycerides,and low density lipoprotein cholesterol in the study group were lower than those in the control group,while high density lipoprotein cholesterol was higher than that in the control group(P<0.05).The plasma specific viscosity,whole blood specific viscosity,whole blood reduced viscosity,and hematocrit of the study group were lower than those of the control group(P<0.05).The levels of calcitonin gene-related peptide and nitric oxide in the study group were higher than those in the control group,while the level of endothelin-1 was lower than that in the control group(P<0.05).Conclusion On the basis of conventional treatment,the use of jiangzhi tongluo soft capsules to treat hyperlipidemia of qi stagnation and blood stasis type can further reduce blood lipids and viscosity,and improve endothelial cell function.