Abstract:Objective To investigate the effect of early bladder function training on the recovery of bladder function and pelvic floor muscle strength in patients after radical surgery for cervical cancer.Methods One hundred and forty patients with cervical cancer from January 2023 to December 2024 who underwent radical surgery in Fujian Medical University Affiliated Min Dong Hospital were selected as the research subjects,and divided into a control group(n=70)and an observation group(n=70),by a random number table method.The control group received routine nursing care,while the observation group received early bladder function training on the basis of the control group.The recovery of bladder function,changes in clinical related indicators,pelvic floor muscle strength level,and improvement of quality of life were compared between the two groups of patients.Results The observation group exhibited superior bladder function and bladder compliance indicators compared to the control group(P<0.05).Additionally,the observation group demonstrated improved postoperative pelvic floor muscle strength and quality of life scores compared to the control group(P<0.05).Conclusion Early bladder function training can improve the bladder compliance of patients after radical surgery for cervical cancer,shorten the time of indwelling catheter,promote the of pelvic floor muscle strength,and improve the bladder function and quality of life of patients.

Abstract:Objective To control the spread of AIDS,reduce the incidence of AIDS,and achieve the goal of ending the public health of AIDS by 2030 for better,targeted interventions and prevention and control measures are proposed.Methods Descriptive epidemiological methods were used to statistically analyze the data of human immunodeficiency virus(HIV)/acquired immune deficiency syndrome(AIDS)in Rui'an City from 2004 to 2023.Results From 2004 to 2023,there were 1294 cases of HIV/AIDS cases currently living in Rui'an City,with an average annual reported incidence rate of 5.02/100,000,the highest rate reached 9.31/100,000,the average annual reported mortality rate was 0.35/100,000,ranking first in the mortality rate of infectious diseases.The reported incidence rate showed an overall upward trend(χ2=16.64,P<0.01).The urban incidence was higher than that of other towns(streets).The male-to-female ratio was 4.32∶1(χ2=420.34,P<0.01),and the male-to-female ratio showed an trend year by year(χ2=6.36,P<0.05),and the proportion of≥50 years old age showed an upward trend(χ2=10.84,P<0.01).The route of infection was mainly sexual transmission,and the trend same-sex transmission increased year by year(χ2=7.71,P<0.01).Conclusion The overall trend of AIDS epidemic in Rui'an City from 2004 to 2023 was first upward and then slowly downward,but the incidence rate is still relatively high,and the prevention and control situation is grim.Especially,the incidence of the elderly continues to rise,and key interventions need to be strengthened.The proportion of same-sex transmission routes has increased year by year,and men who have with men are also key groups for prevention and intervention.

Abstract:Objective To explore the value of coronary computed tomographic angiography(CCTA)and digital subtraction angiography(DSA)in evaluating the degree of coronary artery stenosis in coronary heart disease.Methods A retrospective analysis was conducted on 100 patients with suspected coronary heart disease admitted to Linyi Central Hospital from October 2022 to October 2023.All patients underwent CCTA and DSA.Using DSA results as the gold standard,we evaluated the diagnostic efficacy of CCTA for coronary artery stenosis in coronary heart disease,analyzed the nature of plaques under different degrees of coronary artery stenosis,and further analyzed the differences in examination parameters among patients with mild,moderate,and severe stenosis.Results The diagnostic accuracy of CCTA for coronary artery stenosis was 93.00%,with a sensitivity of 96.63%and specificity of 63.64%.The number of segments diagnosed as mild,moderate,and severe stenosis by DSA were 157,70,and 36,respectively.While the number of segments diagnosed as mild,moderate,and severe stenosis by CCTA were 152,73,and 38,respectively.Kappa analysis showed a high degree of consistency between the two methods.The CCTA examination revealed that calcified plaques and mixed plaques are more common in the mild stenosis group,while non-calcified plaques are more prevalent in the moderate stenosis group.However,the proportions of the three plaque types do not significantly differ in the severe stenosis group.In different grades of stenosis,as the degree of stenosis worsens,minimal lumen area and minimum lumen diameter decreased,while the proportion of area stenosis and diameter stenosis increased(P<0.05).Conclusion Quantitative coronary CT angiography is of great value in evaluating the degree of coronary artery stenosis in coronary heart disease and can provide valuable reference for clinical diagnosis and treatment.

Abstract:Objective To study the application effect of cognitive intervention based on cross-theoretical model in patients with acute ischemic stroke(AIS)treated by mechanical embolectomy.Methods Sixty AIS patients who received mechanical embolectomy in Nanping First Hospital from July 2022 to June 2024 were included in the study.They were divided into a control group(n=30)and a study group(n=30),by a random number table method.The control group was given routine intervention,while the study group was given cognitive intervention based on cross-theoretical model on the basis of routine intervention.The clinical indicators,health behavior,quality of life of two groups were compared.Results The postoperative oral intake time,time of getting out of bed,hospital stay of the research group were significantly shorter than those of the control group,and the scores of National Institute of Health Stroke Scale at 7 days after operation were significantly lower than those of the control group(P<0.05).After the intervention,the scores of the health promoting lifestyle profile-Ⅱ and the generic quality of inventory in the study group were higher than those in the control group(P<0.05).Conclusion Cognitive intervention based on cross-theoretical model can effectively improve the health behavior of patients treated with mechanical embolectomy in AIS,promote the improvement of neurological and cognitive functions,and improve the quality of life.

Abstract:Objective To analyze the correlation between inflammatory factor,oxidative stress factor expression and alveolar bone resorption in gingival crevicular fluid of patients with periodontitis.Methods From May 2022 to May 2024,88 patients with PD admitted to the People's Hospital of Yunyang District of Shiyan City were selected as the study group.Additionally,88 healthy individuals who underwent physical examinations during the same period at the same hospital were selected as the control group.The differences in inflammatory factors,oxidative stress factors,and alveolar bone resorption indicators between the two groups of patients were compared,and the correlation analysis were performed.Results Aspartate-specific cysteine protease 1(Caspase-1),nod-like receptor protein 3(NLRP3),interleukin-1β(IL-1β),apoptosis-associated speck-like protein containing a CARD(ASC),interleukin-18(IL-18),receptor activator of nuclear factor-κB ligand(RANKL),Type I collagen pyridine cross-linked amino-terminal peptide(NTX),matrix metalloproteinase-9(MMP9),and superoxide dismutase(SOD)were higher than those of the control group(P<0.05).Runt-related transcription factor 2(Runx2),osteoprotegerin(OPG),malondialdehyde(MDA),reactive oxygen species(ROS)were lower than those of the control group(P<0.05).Pearson correlation analysis showed that Caspase1,NLRP3,IL-1β,ASC,IL-18,and SOD were positively correlated with RANKL,NTX,and MMP9(P<0.05),and negatively correlated with Runx2 and OPG(P<0.05).MDA and ROS were positively correlated with Runx2 and OPG(P<0.05),and negatively correlated with RANKL,NTX,and MMP9(P<0.05).Conclusion In patients with PD,the expression of inflammatory factors in gingival crevicular fluid is upregulated,oxidative stress levels are elevated,and the imbalance in the RANKL/OPG ratio leads to alveolar bone resorption.This may provide important insights into the pathogenesis and treatment strategies of PD.

Abstract:Objective To study the effects of sensory and perceptual training combined with task-oriented exercise rehabilitation on sensory integration and static postural control in children with spastic cerebral palsy.Methods A total of 84 children with spastic cerebral palsy treated in Tianjin Children's Hospital from March 2023 to June 2024 were selected and divided into a control group and an observation group,with 42 cases in each group by a random number table method.The control group received sensory and perceptual training,while the observation group received task-oriented exercise rehabilitation on the basis of the control group.The clinical effect of the two groups was compared.Results After intervention,both groups showed increased scores on the Berg balance scale and 6-minute walk test distance,with the observation group having higher scores than the control group(P<0.05).Both groups showed decreased scores on the modified Ashworth scale,with the observation group having lower scores than the control group(P<0.05).Both groups showed increased scores on the gross motor function measure,with the observation group having higher scores than the control group(P<0.05).Conclusion After sensory and perceptual training combined with task-oriented exercise rehabilitation,the children with spastic cerebral palsy can significantly improve their sensory integration ability and balance function,and promote their recovery as soon as possible,with good therapeutic effect and high clinical value.

Abstract:Objective To compare the short-term efficacy and prognosis of laparoscopic radical resection and open surgery for patients with liver cancer.Methods Sixty patients with liver cancer admitted to Clinical Medical College of Shaanxi University of Chinese Medicine from January 2023 to March 2024 were selected and divided into a control group(n=30)and an observation group(n=30),by a random number table method.The control group was treated with open surgery,while the observation group was treated with laparoscopic radical resection of liver cancer.The perioperative indicators of the two groups of patients were compared.Results After surgery,the observation group had shorter operation time,postoperative exhaust time,postoperative extubation time,absolute bed rest time,hospitalization time,bowel sound recovery time,and defecation time than the control group(P<0.05).The levels of C-reactive protein,procalcitonin,interleukin-6,and tumor necrosis factor-α in the observation group were lower than those in the control group(P<0.05).The serum albumin of the observation group was higher than that of the control group,while the total bilirubin,alanine aminotransferase,and aspartate aminotransferase were lower than those of the control group(P<0.05).The levels of adrenaline,norepinephrine,and dopamine in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The short-term efficacy and survival prognosis of laparoscopic radical resection for liver cancer are superior to those of open surgery,with this advantage being manifested in various aspects such as postoperative recovery,inflammatory status,organ damage,and stress.

Abstract:Objective To investigate the therapeutic effect of high-dose proton pump inhibitors(PPIs)combined with amoxicillin in combination therapy for patients with Helicobacter pylori(HP).Methods One hundred and sixty cases of HP infection patients admitted to the Second People's Hospital of Jiangyin from May 2023 to May 2024 were randomly divided into a control group and a study group,with 80 cases in each group.The control group was treated with conventional quadruple therapy,while the research group used high-dose PPI combined with amoxicillin for treatment.The HP eradication rate,symptom relief,adverse reactions,and treatment compliance between two groups of patients were compared.Results There was no statistically significant difference in HP eradication rate between the two groups of patients(P>0.05).The relief time of various symptoms in the study group was lower than that in the control group(P<0.05).The incidence of adverse reactions in the research group was lower than that in the control group(P<0.05).The medication adherence of the study group was higher than that of the control group(P<0.05).Conclusion The dual therapy of high-dose PPI combined with amoxicillin has a similar HP eradication effect as conventional quadruple therapy,but its symptom relief is faster,the incidence of adverse reactions is lower,and the patient's medication compliance is higher.

Abstract:Objective To explore the effect of ultrasound-guided visualized acupotomy on lumbar spine range of motion in patients with lower back pain.Methods Ninety patients with lower back pain admitted to the Second Affiliated Hospital of Qiqihar Medical College from January 2024 to December 2024 were collected and divided into a control group and an observation group,with 45 cases in each group by random number table method.The control group accepted lumbar traction,while the observation group accepted ultrasound-guided visualized acupotomy.The treatment effects of the two groups were compared.Results The VAS scores at 1 month and 3 months post-treatment,as well as the ODI scores at 3 months and 6 months post-treatment,were lower in the observation group than in the control group(P<0.05).The FRR values for the erector spinae muscles during extension,flexion,and dynamic muscle endurance were higher in the observation group than in the control group(P<0.05).Conclusion Patients with low back pain who undergo ultrasound-guided visualized acupotomy can experience better enhancement of lumbar muscle strength and myoelectric conduction,as well as reduced pain,thereby improving lumbar function.

Abstract:Objective To explore the application value of suture embracing Nice knot elastic fixation in patients with ankle fractures accompanied by tibiofibular injuries.Methods One hundred and twenty patients with ankle fractures and tibiofibular injuries in Mentougou District Hospital from January to December 2024 were selected and randomly divided into an observation group and a control group,with 60 patients in each group,by a random number table method.The control group accepted cortical bone screw fixation,while the observation group accepted suture wrapped Nice knot elastic fixation.The excellent rate,joint morphology and structure,and ankle joint function indicators were compared between the two groups.Results There were no statistically significant differences in operation duration,fracture healing time,intraoperative blood loss,time to ambulation,and hospital stay between the two groups(P>0.05).The time to full weight-bearing in the observation group was shorter than that in the control group(P<0.05).The excellent and good rate in the observation group was higher than that in the control group(P<0.05).Three months postoperatively,the levels of inferior tibiofibular joint space,medial joint space,and ankle mortise width difference in both groups decreased compared to pre-operative measurements,while the tibiofibular overlap increased compared to pre-operative measurements.However,there were no statistically significant differences between the groups(P>0.05).Three months postoperatively,the ankle joint function scores,dorsiflexion and plantarflexion degrees of the ankle joint in the observation group were higher than those in the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion For patients with ankle fractures accompanied by tibiofibular injuries,using suture wrapped Nice knot elastic fixation can help improve the surgical success rate,ankle joint function,perioperative conditions,and reduce the incidence of complications.

Abstract:Objective To explore the influencing factors of implant failure in patients with periodontitis and construct a risk prediction model.Methods A total of 286 patients with periodontitis who underwent implant treatment in Min Dong Hospital Affiliated to Fujian Medical University from May 2020 to April 2022 were collected,and followed up until April 2025.According to the conditions after 3-year follow-up after implantation,they were divided into a failure group(n=62)and a success group(n=224).Results The proportions of age≥60 years old,diabetes,smoking history,failure to clean teeth regularly,osteoporosis,not brushing teeth after meals,and brushing time<3 minutes in the failure group were all higher than those in the successful group(P<0.05).Multivariate logistic regression analysis showed that age≥60 years old,diabetes,smoking history,irregular teeth cleaning,and osteoporosis were independent risk factors affecting dental implant failure in patients with periodontitis(P<0.05).ROC curve analysis showed that the AUC value,sensitivity and specificity of the comprehensive index constructed by independent risk factors in predicting dental implant failure in patients with periodontitis were 0.742,75.80%and 61.60%,respectively.Conclusion Age≥60 years old,diabetes,smoking history,failure to clean teeth regularly,and osteoporosis are independent risks affecting dental implant failure in patients with periodontitis.The risk prediction model constructed based on the above indicators has certain predictive value and can provide a reference basis for the early clinical identification of high-risk populations.

Abstract:Objective To explore the influencing factors of local recurrence risk after colorectal cancer surgery.Methods The clinical data of 149 colorectal cancer patients admitted to Quanzhou First Hospital from January 2022 to January 2024 were retrospectively selected.All patients were followed up for 1 year after surgery,and they were divided into a recurrence group(n=31)and a non-recurrence group(n=118)according to whether local recurrence occurred during the follow-up period.The clinical data of two groups of patients were compared to screen the influencing factors of local recurrence after radical resection of colorectal cancer,and draw a receiver operating characteristic(ROC)curve to analyze the predictive value.Results There were statistically significant differences in age,TNM staging,intraoperative blood transfusion,and pathological margin status between the two groups(P<0.05).Multivariate logistic regression results showed that age,TNM stage,and pathological margin status were risk factors for local recurrence after radical resection of colorectal cancer(P<0.05).The combined AUC of each factor for local recurrence after radical resection of colorectal cancer was higher than that of single factor prediction(P<0.05).Conclusion Age,TNM stage and pathological margin status are all risk factors for local recurrence after colorectal cancer surgery.The combination of the three has a relatively high predictive value for local recurrence after colorectal cancer surgery.

Abstract:Objective To reveal the clinical efficacy of Kangfuxin Liquid combined with Mayinglong Hemorrhoid Ointment in the treatment of patients with external hemorrhoid surgery.Methods A total of 108 patients who underwent external hemorrhoid surgery in Fujian Normal University Hospital from September 2022 to December 2024 were selected as the research subjects.They were divided into a control group and an observation group by a random number table method,with 54 patients in each group.The control group received external application of Kangfuxin solution after surgery,while the observation group received external application of Kangfuxin solution combined with Mayinglong Shexiang Hemorrhoids Ointment.The efficacy,wound healing,pain level,inflammatory factors,and quality of life were compared between the two groups.Results Two weeks after treatment,the total effective rate in the observation group was significantly higher than that in the control group(P<0.05).The scores of wound edema,wound granulation growth,and wound exudate in the observation group were significantly lower than those in the control group(P<0.01).The visual analogue scale scores in the observation group were significantly lower than those in the control group at 7 days and 2 weeks after treatment(P<0.05).The levels of IL-1β,IL-6,IL-8,IL-17,TNF-α,and MCP-1 in wound exudate of the observation group were significantly lower than those of the control group 1 week after treatment(P<0.05).Two weeks after treatment,all dimension scores of the SF-36 scale in the observation group were significantly higher than those in the control group(P<0.05).Conclusion Postoperative application of Kangfuxin Liquid combined with Mayinglong Hemorrhoid Ointment is more effective than monotherapy for external hemorrhoid patients.It can effectively reduce pain,inhibit inflammation,accelerate wound healing,and thus improve quality of life.

Abstract:Objective To explore the effect of steep axis corneal relaxing incisions in patients undergoing refractive cataract surgery.Methods A total of 180 patients who underwent refractive cataract surgery at Jian'ou Municipal Hospital of Fujian Province from May 2022 to May 2024 were selected and divided into an observation group and a control group,with 90 patients in each group,based on the different surgical incision positions.The observation group made the main incision on the steep meridian of the cornea and made a penetrating full-thickness transparent corneal incision on the opposite side.The control group only made incisions along the steep axis meridian of the cornea.Compare the corneal astigmatism,uncorrected visual acuity,and best corrected visual acuity before surgery,1 month after surgery,and 3 months after surgery between two groups.Results One month after surgery,the corneal astigmatism in both groups decreased compared to before surgery,and the observation group was significantly lower than the control group(P<0.05).There was no significant difference in corneal astigmatism between the observation group at 3 months after surgery and 1 month after surgery(P>0.05).The corneal astigmatism degree in the control group increased significantly at 3 months after surgery compared to 1 month after surgery(P<0.05).The corneal astigmatism degree of the observation group was significantly lower than that of the control group at 3 months after surgery(P<0.05).One month after surgery,both groups showed an improvement in uncorrected visual acuity and best corrected visual acuity compared to preoperative levels(P<0.05).There was no significant difference in uncorrected visual acuity and best corrected visual acuity between the two groups at 1 month after surgery(P>0.05).There was no significant difference in uncorrected visual acuity and best corrected visual acuity between the two groups at 3 months after surgery compared to 1 month after surgery(P>0.05).There was no significant difference in the uncorrected visual acuity and best corrected visual acuity between the two groups at three months after surgery(P>0.05).Conclusion For patients undergoing refractive cataract surgery,using a steep axis corneal relaxing incision can effectively correct corneal astigmatism,and the effect is more stable than using only the steep axis meridian as a single incision.It is worthy of promotion and application.

Abstract:Objective To explore the application effect of whole-course management nursing mode in lymphoma patients undergoing chemotherapy.Methods Ninety lymphoma patients who received chemotherapy treatment in the Hematology Department of Sanming First Hospital from January 2023 to November 2024 were selected as the study subjects.All patients were randomly divided into a routine group and a whole-course management group using a random number table method,with 45 patients in each group.The routine group implements routine nursing,while the whole-course management group implements whole-course management nursing.Compare the incidence of complications and adverse reactions and nursing satisfaction between two groups,and compare the negative emotions,psychological resilience,sleep quality,self-efficacy,and quality of life before and after intervention between the two groups.Results There was no significant difference in the scores of negative emotions,psychological resilience,sleep quality,self-efficacy,and quality of life between the two groups before intervention(all P>0.05).After intervention,the negative emotions,psychological resilience,sleep quality,self-efficacy,and quality of life scores of both groups were improved,and the scores of the above indicators in the whole-course management group were significantly better than those in the routine group after intervention(all P<0.05).The total incidences of complications and adverse reactions in the whole-course management group were significantly lower than those in the routine group,and the nursing satisfaction was significantly higher than that in the routine group(all P<0.05).Conclusion In lymphoma patients undergoing chemotherapy,the whole-course management nursing model can significantly improve the negative emotions,sleep quality and mental resilience of patients,and effectively reduce the occurrence of complications and adverse reactions,making it worth promoting and using.

Abstract:Objective To investigate the effect of computed tomography perfusion(CTP)and computed tomography angiography(CTA)in the diagnosis of acute ischemic stroke.Methods A total of 115 suspected acute ischemic stroke patients admitted to Tianjin Hongqiao Hospital from June 2019 to June 2024 were selected as the study subjects.All patients voluntarily underwent CTP,CTA,and digital subtraction angiography(DSA)examinations.Using DSA examination results as the gold standard,compare and analyze the diagnostic efficacy of CTP,CTA alone,and CTP combined with CTA examination,and analyze the imaging indicators of CTP examination.Results Out of 115 suspected patients with acute ischemic stroke,80 cases were diagnosed.Compared with CTP or CTA examinations alone,CTP combined with CTA examination had significantly higher diagnostic accuracy,specificity,and sensitivity,lower misdiagnosis and missed diagnosis rates(all P<0.05).The CTP examination results showed that there were significant differences in cerebral blood flow,cerebral blood volume,mean transit time,and peak time between the infarcted area and the semi dark area and the control area(P<0.05).Conclusion The use of CTP combined with CTA examination in patients with acute ischemic stroke has better diagnostic efficacy than using CTP or CTA examination alone,and is worthy of clinical promotion and use.

Abstract:Objective To explore the effect of personalized nursing in patients treated with coronary stent implantation.Methods A total of 150 patients with coronary heart disease who were received coronary stent implantation in the 951st Hospital of the PLA Ground Force from August 2023 to July 2024 were selected as the study subjects.All patients were randomly divided into a control group and a personalized group with 75 patients in each group by random number table.The control group received routine nursing,while the personalized group received personalized nursing.Compare the changes in vital signs during the perioperative period,surgical related indicators,nursing satisfaction,and negative emotions before and after nursing between two groups.Results At admission,there was no significant difference in heart rate,systolic blood pressure,and diastolic blood pressure between the two groups(all P>0.05).Immediately before surgery and 20 minutes after the start of surgery,the heart rate,systolic blood pressure,and diastolic blood pressure of the personalized group were significantly lower than those of the control group(all P<0.05).The personalized group had shorter surgical preparation time and operation time than the control group,and higher intraoperative cooperation than the control group(all P<0.05).After nursing,the scores of self-rating scales of anxiety and depression in both groups were lower than before nursing,and the personalized group had significantly lower scores of self-rating scales of anxiety and depression than the control group after nursing(all P<0.05).The nursing satisfaction scores of personalized group in all dimensions were significantly higher than those of the control group(all P<0.05).Conclusion Personalized nursing for patients undergoing coronary stent implantation can further improve negative emotions,reduce stress reactions,and shorten surgical time compared to routine nursing.It is worth promoting and using.

Abstract:Objective To explore the application effect of operating room nursing based on the concept of quantitative evaluation in patients undergoing acute calculous cholecystitis surgery.Methods A total of 60 patients with acute calculous cholecystitis who underwent surgical treatment at Shaanxi Traffic Hospital from September 2021 to September 2024 were selected as the study subjects.All patients were randomly divided into a quantitative group and a control group,with 30 patients in each group,using a random number table method.The quantitative group implemented operating room nursing based on the concept of quantitative evaluation,while the control group implemented routine operating room nursing.Compare the nursing satisfaction,negative emotion,and physiological stress responses before and after nursing between two groups.Results Before nursing,there was no significant difference in negative emotions and physiological stress responses between the two groups(all P>0.05).After nursing,the negative emotions and physiological stress reactions of quantitative group were significantly lower than those of control group(all P<0.05).The nursing satisfaction of quantitative group was significantly higher than that of control group(P<0.05).Conclusion The operating room nursing based on quantitative evaluation concept can achieve satisfactory results,improve patients'negative emotions,and alleviate physiological stress reactions in patients undergoing acute calculous cholecystitis surgery.It is worth promoting and using.

Abstract:Objective To explore the postoperative analgesic effect of bupivacaine liposome intercostal nerve block for patients undergoing thoracoscopic lung surgery.Methods A total of 220 patients who underwent elective thoracoscopic lung surgery at Sanming First Hospital from January to December 2024 were selected as the study subjects.All patients were randomly divided into a bupivacaine liposome group and a ropivacaine group using a random number table method,with 110 patients in each group.The bupivacaine liposome group received bupivacaine liposome intercostal nerve block,while the ropivacaine group received ropivacaine intercostal nerve block.Compare the pain levels at different time points and states after surgery between two groups,as well as the incidence of complications and adverse events within 72 hours after surgery.Results There were no significant difference in the visual analogue scale(VAS)pain scores between the two groups at 2 and 6 hours after surgery,whether in a resting or active state(P>0.05).The VAS pain scores of the bupivacaine liposome group were significantly lower than those of the ropivacaine group at 12,24,48,and 72 hours after surgery(P<0.05).The total incidence of complications within 72 hours after surgery in the bupivacaine liposome group was significantly lower than that in the ropivacaine group(P<0.05).Both groups of patients did not experience any adverse events,such as local hematoma,pneumothorax,nerve injury,or block failure within 72 hours after surgery.Conclusion The use of bupivacaine liposome intercostal nerve block in patients undergoing thoracoscopic lung surgery can effectively alleviate postoperative pain,reduce the incidence of postoperative complications and adverse events,promote patient recovery,and is worthy of clinical promotion and application.

Abstract:Objective To explore the differences in perioperative prognosis between modified single position transperitoneal laparoscopic nephroureterectomy(MSPTLNU)and retroperitoneal laparoscopic nephroureterectomy(RLNU)in the treatment of upper urinary tract urothelial carcinoma(UTUC).Methods The clinical data of 71 patients with upper urinary tract urothelial carcinoma who underwent laparoscopic nephroureterectomy at the Fourth Affiliated Hospital of China Medical University from August 8th,2015 to December 31st,2024 were retrospectively analyzed.All patients were divided into a MSPTLNU group and a RLNU group based on different surgical approaches.Clinical data,perioperative bleeding volume,surgical duration,hospital stay,and other indicators were compared between the two groups.Results There was no significant difference in age,gender,medical history,oncological characteristics and other data between the two groups(P>0.05).The MSPTLNU group had significantly shorter surgical duration,postoperative drainage tube retention time,and hospital stay than those of the RLNU group(all P<0.05).The intraoperative blood loss in the MSPTLNU group was less than that in the RLNU group,but the difference was not significant(P>0.05).Conclusion The MSPTLNU is used for patients with UTUC,which has certain advantages in perioperative prognosis compared to RLNU and has good clinical application prospects.It is worth promoting and using.