Correlation Study on the Risk of Local Recurrence after Surgery of Colorectal Cancer

ZHANG Fengshun; LIN Siyan; ZHANG Kunhe

doi:10.3969/j.issn.1672-7185.2025.10.019

Abstract：Objective To explore the influencing factors of local recurrence risk after colorectal cancer surgery.Methods The clinical data of 149 colorectal cancer patients admitted to Quanzhou First Hospital from January 2022 to January 2024 were retrospectively selected.All patients were followed up for 1 year after surgery,and they were divided into a recurrence group(n=31)and a non-recurrence group(n=118)according to whether local recurrence occurred during the follow-up period.The clinical data of two groups of patients were compared to screen the influencing factors of local recurrence after radical resection of colorectal cancer,and draw a receiver operating characteristic(ROC)curve to analyze the predictive value.Results There were statistically significant differences in age,TNM staging,intraoperative blood transfusion,and pathological margin status between the two groups(P<0.05).Multivariate logistic regression results showed that age,TNM stage,and pathological margin status were risk factors for local recurrence after radical resection of colorectal cancer(P<0.05).The combined AUC of each factor for local recurrence after radical resection of colorectal cancer was higher than that of single factor prediction(P<0.05).Conclusion Age,TNM stage and pathological margin status are all risk factors for local recurrence after colorectal cancer surgery.The combination of the three has a relatively high predictive value for local recurrence after colorectal cancer surgery.