Abstract:Objective To explore the effects of combined treatment with two drugs on left ventricular remodeling and prognosis in patients with chronic heart failure.Methods A retrospective analysis was conducted on 90 patients with chronic heart failure admitted to Anyang People's Hospital from March 2023 to October 2024.They were divided into a control group(treated with metoprolol succinate sustained-release tablets)and an observation group(treated with sacubitril/valsartan sodium tablets in addition to the control group),with 45 cases in each group.The left ventricular remodeling indicators,vascular endothelial function,neuroendocrine hormone indicators,and adverse reactions before and after treatment were compared between two groups.Results After treatment,the left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)of both groups were lower than those before treatment,and the indexes of the observation group were lower than those of the control group.The left ventricular ejection fraction(LVEF)of both groups were higher than those before treatment,and the index of the observation group was higher than that of the control group(P<0.05).After treatment,the levels of serum calcitonin gene-related peptide(CGRP)and nitric oxide(NO)in both groups were higher than those before treatment,and the indexes of the observation group were higher than those of the control group.The level of endothelin(ET)in both groups were lower than those before treatment,and the index of the observation group was higher than that of the control group(P<0.05).After treatment,the levels of various neuroendocrine hormone indicators in both groups were improved compared with those before treatment,and the improvement in the observation group was more significant(P<0.05).The comparison of the total incidence of adverse reactions between the two groups showed no statistically significant difference(P>0.05).Conclusion For patients with chronic heart failure,the combined treatment with the above two drugs can effectively inhibit the process of ventricular remodeling,regulate the levels of neuroendocrine hormone indicators,and improve vascular endothelial function.Moreover,it shows good safety in clinical application.

Abstract:Objective To explore the clinical efficacy and safety of local rotating flaps combined with growth factor gel in the treatment of sacrococcygeal pressure ulcers,and to provide an optimized treatment plan for sacrococcygeal pressure ulcers.Methods Eighty patients with sacrococcygeal pressure ulcers admitted to Zhoukou Orthopedic Hospital from January 2023 to May 2025 were selected as the research subjects and divided into an observation group and a control group according to the random number table method,with 40 cases in each group.Patients in the control group received conventional dressing change treatment,while patients in the observation group received classic local rotating flap surgery combined with growth factor gel treatment.The recovery conditions of the two groups of patients were compared,including the degree of pain,inflammation-related indicators,recovery of pressure ulcers and the occurrence of adverse reactions before and after treatment Results The disappearance time of exudate and the recovery time of patients in the observation group were shorter than those in the control group,and the number of dressing changes was less than that in the control group,with statistilally signficat differences(P<0.05).After treatment,the Visual Analogue Scale(VAS)scores of the two groups of patients gradually decreased,and the scores of the observation group at each time point were lower than those of the control group,with statistically significant differences(P<0.05).After treatment,the white blood cell count(WBC),the levels of serum C-reactive protein(CRP)and procalcitonin(PCT)of patients in both groups gradually decreased,and the levels of the above indexes of the observation group at each time point were lower than those of the control group,with statistically significant differences(P<0.05).After treatment,the pressure ulcer healing assessment scale(PUSH)scores of the two groups of patients gradually decreased,and the scores of the observation group at each time point were lower than those of the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups of patients(P>0.05).Conclusion Local rotating flaps combined with growth factor gel in the treatment of sacrococcygeal pressure ulcers can promote recovery,alleviate patients'pain and inflammatory responses,and have relatively high safety.

Abstract:Objective To observe the effect of progressive balance and coordination training after total hip arthroplasty(THA)in the elderly.Methods From May 2022 to May 2025,102 elderly patients with THA admitted to Hebi People's Hospital were selected as the research subjects.They were divided into a control group and an observation group according to the random number table method,with 51 cases in each group.The control group patients received postoperative routine rehabilitation training,while the observation group patients received postoperative progressive balance and coordination training.The lower limb motor function,hip joint function,fall risk and nursing satisfaction of the two groups before and after the intervention were compared.Results After 8 weeks of intervention,the Fugl-Meyer lower limb motor function assessment scale(FMA-LE)score and Harris hip joint score(HHS)of the observation group patients were higher than those of the control group,and the differences were statistically significant(P<0.05);4 weeks and 8 weeks after the intervention,the scores of the Tinetti balance and gait scale(TPOM)of the observation group patients were higher than those of the control group,and the differences were statistically significant(P<0.05);the total nursing satisfaction rate of the observation group patients was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion In elderly patients with THA,actively conducting progressive balance and coordination training after surgery can not only effectively improve the hip joint function of patients,but also reduce the fall risk after surgery,promote the reconstruction of lower limb motor function,and improve nursing satisfaction.

Abstract:Objective To explore the effect of Reunion of Heat-toxin Ning injection combined with Montelukast Sodium and Azithromycin in the treatment of mycoplasma pneumonise pneumonia(MPP)in children.Methods A total of 106 children with MPP who visited Shangcai Chongyang Hospital from June 2023 to January 2025 were selected as the research subjects.They were randomly divided into a control group and an observation group,with 53 cases in each group.The control group received treatment with Montelukast Sodium+Azithromycin,while the observation group received treatment with Reunion of Heat-toxin Ning injection in addition to the treatment of the control group.The infammatory-related indicators,lung function,traditional Chinese medicine(TCM)syndrome scores before and after treatment,clinical efficacy and adverse reactions were compared between the two groups.Results After treatment,the levels of serum ferritin(SF),C-reactive protein(CRP),lactate dehydrogenase(LDH)and the scores of severe fever,wheezing and coughing in the observation group were lower than those in the control group,and the tidal volume(V-T),peak time ratio(T-PTEF/t-E),and inspiratory mid-flow rate to expiratory mid-flow rate ratio(MTIF/MTEF)were greater than those in the control group,the above differences were statistically significant(P<0.05);the total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05);there was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion For children with MPP,the treatment with Heat-toxin Ning injection,combined with Montelukast Sodium and Azithromycin,can inhibit inflammatory responses,improve lung function,alleviate clinical symptoms,enhance clinical efficacy,and does not increase adverse reactions.

Abstract:Objective To analyze the impact of the life network-based nursing model on negative emotions,self-management ability and quality of life in elderly patients with coronary heart disease.Methods A total of 102 elderly patients with coronary heart disease admitted to Zhengzhou Second People's Hospital from August 2022 to August 2024 were selected as the research subjects and randomly divided into a control group and a study group,with 51 cases in each group.Patients in the control group received conventional nursing measures,while those in the study group received the life network-based nursing model on the basis of the control group.The negative emotions,self-management ability and quality of life of the two groups were compared before and after the intervention.Results After the intervention,the scores of the Hamilton depression scale(HAMD)and the Hamilton anxiety scale(HAMA)in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the intervention,the scores of the coronary heart disease self-management scale(CSMS)in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).After the intervention,the scores of the World Health Organization quality of life-BREF(WHOQOL-BREF)in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The life network-based nursing model can effectively improve the negative emotions of elderly patients with coronary heart disease,and enhance their quality of life and self-management ability.

Abstract:Objective To explore the relationship between serum uric acid(SUA)and high-sensitivity cardiac troponin Ⅰ(hs-cTnI)levels and cardiac function prognosis in patients with acute myocardial infarction(AMI).Methods A total of 141 AMI patients admitted to the Panyu Branch of the Second Affiliated Hospital of Guangzhou Medical University from January 2023 to December 2024 were selected as the research subjects.Their SUA and hs-cTnI levels were detected,and echocardiography was performed to record left ventricular end-systolic diameter(LVESD),left ventricular end-diastolic diameter(LVEDD),left ventricular ejection fraction(LVEF),and the degree of coronary artery disease(Gensini score).The severity of patients'heart failure was evaluated according to the Killip classification,and the patients were divided into the Killip grade≥Ⅱ group and the Killip grade<Ⅱ group.The differences in SUA and hs-cTnI levels between patients of different Killip grades and patients with different types of myocardial infarction were compared,and correlation and multivariate regression analyses were conducted.Results:There was no statistically significant difference in general data between the Killip grade≥Ⅱ group and the Killip grade<Ⅱ group(P>0.05);there were statistically significant differences in SUA levels and peak serum hs-cTnI levels among patients with Killip grades I to IV(P<0.05);the SUA levels and peak serum hs-cTnI levels of patients with ST-segment elevation myocardial infarction(STEMI)were higher than those of patients with non-ST-segment elevation myocardial infarction(NSTEMI),and the differences were statistically significant(P<0.05).The correlation analysis showed that the SUA levels and peak serum hs-cTnI in AMI patients were negatively correlated with LVEF and positively correlated with LVESD,LVEDD,and Gensini score(P<0.05).Multivariate regression analysis showed that after adjusting for confounding factors,SUA and peak hs-cTnI remained independent risk factors for Killip classification≥II heart failure in patients(P<0.05).Conclusion The SUA and peak hs-cTnI levels in AMI patients are significantly correlated with the severity of Killip classification,and their elevation is an important risk factor for cardiac function deterioration.

Abstract:Objective To explore the application effect of comfort nursing based on evidence-based theory in pediatric surgical anesthesia nursing.Methods A retrospective study was conducted on 120 children undergone surgical anesthesia and were treated at Kaifeng Children's Hospital from March 2023 to March 2025.They were divided into an observation group and a control group according to different nursing methods,with 60 cases in each group.The children in the control group were given traditional nursing methods,while those in the observation group were given comfortable nursing methods based on evidence-based theory.The recovery-related indicators,postoperactivo vital signs,awakening restlessness,psychological state before and after the operation,and satisfaction of the two groups of children were compared.Results The complete awakening time,recovery time of spontaneous breathing,stay in the room and hospital stay of the children in the observation group were all shouter than those in the control group,and the differences were statistically significant(P<0.05).After the operation,the heart rate of children in the observation group was lower than that in the control group,while the mean arterial pressure,blood oxygen saturation and awakening body temperature were all higher than those in the control group,the differences were statistically significant(P<0.05).The total incidence of awakening restlessness in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).One week after the operation,the scores of the screen for anxiety related emotional disorders in children(SCARED),the symptom rating scale for depression in children(DSRSC),and the medical fear scale for children(CMFS)in the observation group were all lower than those in the control group,and the differences were statistically significant(P<0.05).The overall satisfaction rate of the children in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Comfort care based on evidence-based theory can promote the recovery of children,stabilize vital signs,reduce awakening restlessness,improve psychological state and enhance satisfaction.

Abstract:Objective To analyze the clinical effect of modified Xiaoqinglong Decoction combined with antibacterial drugs in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods The research subjects were 92 patients with AECOPD admitted to the Mianchi County Hospital of Traditional Chinese Medicine from June 2021 to June 2023.They were grouped into a control group and an observation group using the random number table method,with 46 cases in each group.Patients in the control group received treatment with antibacterial drugs alone,while those in the observation group received treatment with antibacterial drugs combined with modified Xiaoqinglong Decoction.The therapeutic effects of the two groups of patients were compared,as well as the blood gas analysis indicators,traditional Chinese medicine(TCM)syndrome scores,lung function,inflammation-related indicators before and after treatment,and the occurrence of adverse reactions.Results After the treatment,the total effective rate of treatment and partial pressure of oxygen in the observation group were higher than those in the control group,the score of coughing,wheezing,shortness of breath,excessive phlegm,white and thin phlegm,partial pressure of carbon dioxide,levels of serum interleukin-6,C-reactive protein and tumor necrosis factor-α were lower than those in the control group.The peak values of forced respiratory volume in the first second,forced vital capacity and expiratory flow were greater than those in the control group,and the differences were statistically significant(P<0.05).No aduerse reautions occurred in either group of patients.Conclusion The modified Xiaoqinglong Decoction combined with antibacterial drugs can effectively alleviate the clinical symptoms of AECOPD patients,improve blood gas analysis indicators,reduce inflammatory responses,enhance lung function,and does not increase the risk of adverse reactions.

Abstract:Objective To analyze the impact of comfort-based nursing for eating and fever management on the improvement of symptoms in children with infectious mononucleosis.Methods A total of 84 children with infectious mononucleosis admitted to Anyang Maternal and Child Health Hospital from March 2023 to September 2024 were selected as the research subjects.They were divided into a control group and an observation group according to the random number table method,with 42 cases in each group.The control group received basic routine care,while the observation group received comfort-based nursing for eating and fever management in addition to the control group.The symptom resolution time,family satisfaction,anxiety and depression before and after the intervention,sleep quality,quality of life,and complication occurrence of the two groups were compared.Results The symptom resolution time of fever,pharyngitis,rash,lymph node enlargement,and liver and spleen enlargement in the observation group were shorter than that in the control group,and the differences were statistically significant(P<0.05);The total satisfaction rate of family care in the observation group was 95.24%,higher than 80.95%in the control group,and the difference was statistically significant(P<0.05);After the intervention,the state-trait anxiety scale,child depression disorder self-rating scale,and simplified Chinese version of pediatric sleep questionnaire(PSQ)scores of the two groups were lower than those before the intervention,and the above indexes of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05);After the intervention,the general health,physiological function,mental health,and emotional function scores of the mini-health status questionnaire of the two groups were higher than those before the intervention,and the above indexes of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05);The total complication rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Comfort-based nursing for eating and fever management for children with infectious mononucleosis can accelerate the relief of symptoms,improve family satisfaction and the quality of life of children,and effectively improve the psychological state and sleep quality of children,and reduce the incidence of complications.

Abstract:Objective To explore the construction of"non-accompanied wards"and the operation mechanism of hierarchical accompaniment in tertiary public hospitals based on self-care theory.Methods A questionnaire survey was conducted among 231 inpatients who voluntarily participated in the research in the"non-accompanied wards"of Shenzhen Third People's Hospital from May 2024 to November 2024.General information,the acute physiology and chronic health evaluation Ⅱ(second edition)(APACHE Ⅱ)scale,the Barthel index scale,the service demand questionnaire for graded nursing patients,and the questionnaire on the implementation status of accompanying services were used to statistically analyze the needs and current situation of patients and assess the correlation.Results A today of 182 valid questionnaires were retrieved(with an effective recovery rate of 78.79%);The comparison of the scores of care needs among patients with different marital statuses,income levels,care levels,APACHE Ⅱ grades and Barthel index grades showed statistically significant differences(P<0.05).The scores of the overall situation and basic needs,rehabilitation needs,and safety needs of all patients were compared with the actual implementation scores,and the differences were statistically significant(P<0.05).The nursing level and Barthel index grade were negatively correlated with the duration of 24-hour care,while the APACHE II score was positively correlated with the duration of 24-hour care(all P≤0.01).Conclusion When providing companion services,the health status and self-care ability of patients should be combined to rationally allocate companion personnel,and the companion personnel who care for multiple patients simultaneously should be precisely allocated.

Abstract:Professor Li Yiming based on the theory of"the lesser yang is the pivot",proposed that"improper adjustment of the governor vessel and imbalance of yin and yang"was the core pathogenesis of insomnia related to emotions,and established the treatment principle of"adjusting the governor vessel and harmonizing yin and yang".His clinical practice used Xiao Chai Hu Decoction as the basic prescription,through precise diagnosis and flexible modification,significantly improved the sleep quality of patients.The authors of this article systematically summarized Professor Li's academic thoughts and clinical experience in treating insomnia with the modified Xiaochaihu Decoction for sleep,combined with typical medical cases,analyzed the diagnosis and treatment system of"dispelling the lesser yang,adjusting the qi mechanism,and calming the mind",providing important references for the treatment of insomnia with traditional Chinese medicine.

Abstract:Objective To explore the clinical efficacy of the combination of traditional Chinese medicine five-element music and heat-sensitive moxibustion in the treatment of functional constipation.Methods A total of 40 patients with functional constipation admitted to Jiujiang NO.1 People's Hospital from June 2022 to December 2024 were selected as the research subjects and randomly divided into a control group and an experimental group,with 20 cases in each group.All patients received routine care.The control group was treated with lactulose oral solution,while the experimental group received the combination of traditional Chinese medicine five-element music and heat-sensitive moxibustion on this basis.The severity of constipation,traditional Chinese medicine(TCM)syndrome scores,quality of life,and nursing satisfaction were compared before and after treatment in both groups.Results After treatment,the Kessler constipation scoring scale(KESS)score of the experimental group was lower than that of the control group,with a statistically significant difference(P<0.05).After treatment,the scores of main symptoms,secondary symptoms,and total scores of the experimental group were lower than those of the control group,with statistically significant differences(P<0.05).After treatment,the scores of each dimension and the total score of the patient assessment of constipation quality of life(PAC-QOL)of the experimental group were lower than those of the control group,with statistically significant differences(P<0.05).The overall satisfaction rate of patient care in the experimental group was higher than that of the control group,with a statistically significant difference(P<0.05).Conclusion The combination of traditional Chinese medicine five-element music and heat-sensitive moxibustion is effective in treating functional constipation,significantly improving symptoms,enhancing quality of life,and having high acceptance.

Abstract:Objective To investigate the current status of helicobacter pylori(Hp)infection among Lisu residents in Xinshan Township,Miyi County,explore the related risk factors of infection,provide a reference for the prevention and control of Hp infection in this area,and offer a theoretical basis for the prevention and treatment of gastric neoplastic diseases.Methods A questionnaire survey combined with ¹⁴ C-urea breath test was conducted among 517 residents of the Lisu ethnic group in Xinshan Township,Miyi County from January 2024 to June 2025 to understand the infection status of Hp in the population and analyze the risk factors related to infection.Results Among the 517 residents,277 cases were positive for Hp and 240 cases were negative,with an infection rate of 53.58%.There were statistically significant differences between the two groups of patients in terms of age,spouse Hp infection,drinking history,shared tableware and chewing feeding(P<0.05).Multivariate analysis showed that advanced age,spouse Hp infection,alcohol consumption history,shared tableware and chewing feeding were all independent risk factors for Hp infection(P<0.05).Conclusion The infection rate of Hp among Lisu residents in Xinshan Township,Miyi County is relatively high.Advanced age,spouse Hp infection,drinking history,sharing tableware and chewing feeding are all independent risk factors for Hp infection,which require effective prevention and control and sufficient attention.

Abstract:Objective To systematically evaluate the multidimensional therapeutic effects of Buxu Decoction combined with Shenge Powder integrated with conventional Western medicine in high-risk patients with stable chronic obstructive pulmonary disease(COPD).Methods Ninety patients with stable COPD treated at Zhoukou People's Hospital from January 2022 to October 2024 were selected as the research object and randomly divided into a control group(conventional Western medicine therapy)and an observation group(integrated Chinese and Western medicine therapy),with 45 patients in each group.Comparisons were made between the two groups regarding the time to first moderate-to-severe acute exacerbation,nymber of occurences of moderate-to-severe acute exacerbations during treatment,traditional Chinese medicine(TCM)syndrome scores,pulmonary ventilation function parameters,laboratory indicators,quality of life before and after treeotment,and rates of rehospitalization and emergency department visits due to acute exacerbations.Results The time to first moderate-to-severe acute exacerbation was longer in the observation group than that in the control group,while the number of moderate-to-severe acute exacerbations was significantly lower in the observation group(P<0.05).After treatment,TCM syndrome scores were significantly lower thow that in the observation group compared to the control group(P<0.05).Post-treatment improvements in forced vital capacity(FVC),forced expiratory volume in one second(FEV1),and FEV1/FVC ratio were greater in the observation group(P<0.05).Peripheral blood cluster of differentiation(CD)4⁺ level was higher in the observation group,while the levels of CD8⁺,serum interleukin(IL)-6,and tumor necrosis factor-α(TNF-α)were lower(P<0.05).The Saint George's Respiratory Questionnaire(SGRQ)scores were lower in the observation group after treatment(P<0.05).The rehospitalization and emergency visit rates were significantly lower in the observation group(P<0.05).Conclusion Integrating Buxu Decoction and Shenge Powder with conventional Western medicine significantly prolongs the time to first moderate-to-severe acute exacerbation and reduces the annual frequency of exacerbations in high-risk patients with stable COPD.Additionally,this combined approach improves TCM clinical symptoms,enhances pulmonary function,optimizes CD4⁺ and CD8⁺T-lymphocyte subset distribution,reduce key inflammatory factors such as IL-6 and TNF-α,and ultimately improves overall quality of life while significantly reducing the risks of rehospitalization and emergency visits.

Abstract:Objective To explore the clinical application effect of amboxol and clenbuterol combined with azithromycin sequential therapy in the treatment of children with mycoplasma pneumoniae pneumonia(MPP).Methods A total of 80 children with MPP admitted to Xiping County People's Hospital from August 2022 to February 2025 were selected as the research subjects.They were divided into a control group and an observation group according to the random number table method,with 40 cases in each group.Both groups of children were given routine treatment.The children in the control group received azithromycin sequential therapy,and the children in the observation group were treated in addition with amboxol and clenbuterol.The clinical symptom improvement time and hospitalization time,serum inflammatory factor levels before and after treatment,lung function,and adverse reactions of the two groups of children were compared.Results The clinical symptom relief time and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant(P<0.05);after treatment,the levels of serum interleukin-6,C-reactive protein,and interferon-γ in the observation group were lower than those in the control group,and the maximum expiratory flow rate,forced vital capacity,and forced expiratory volume in the first second were higher than those in the control group.The above differences were statistically significant(P<0.05);there was no statistically significant difference in the total incidence of adverse reactions between the two groups of children(P>0.05).Conclusion For children with MPP,combined use of amboxol and clenbuterol on the basis of azithromycin sequential therapy can shorten the clinical symptom improvement time and hospitalization time,reduce the inflammatory response of children,improve lung function,and does not significantly increase adverse reactions.

Abstract:As a specialized work on exogenous diseases,the Treatise on Febrile Disorders has relatively few discussions on acupuncture and moxibustion,and most of them are brief records,in-depth research on its acupuncture and moxibustion provisions is unique significance.This article takes Article 24 as the entry point and discusses"needling Fengchi and Fengfu first"from the perspectives of the sequence of acupuncture and the administration of Guizhi Decoction,the interpretation of acupoint names,the main therapeutic effects of acupoints,the theory of opening,closing and pivot,and modern medicine.It analyzes and reveals the wisdom of the sequence of acupuncture and medicine,the scientific nature of acupoint selection,and the connection between ancient and modern medicine from multiple dimensions,with the aim of providing new ideas for the annotation of the article on the combination of acupuncture and medicine.

Abstract:Objective To analyze the efficacy of Cr,Er:YSGG laser combined with gallic acid water extract in orthodontic patients with chronic periodontitis and its influence on periodontal inflammation.Methods Sixty orthodontic patients with chronic periodontitis who visited Huangdao District Central Hospital of Qingdao from January 2024 to January 2025 were selected as the research subjects and randomly divided into a control group(receiving full-mouth periodontal basic treatment combined with Cr,Er:YSGG laser irradiation)and an experimental group(receiving gallic acid water extract intervention on the basis of the control group),with 30 cases in each group.The clinical efficacy,periodontal indicators,oral health status,and gingival crevicular fluid inflammatory-related indicators before and after treatment of the two groups were compared.Results The total clinical effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the bleeding index(SBI),periodontal probing depth(PD),clinical attachment loss(CAL),plaque index(PLI),oral malodor sensory(OS)score,brief oral health status examination(BOHSE)score,the levels of interleukin(IL)-1β,IL-6 in gingival crevicular fluid,white blood cells,and neutrophils in both groups were lower than those before treatment,and those in the experimental group were lower than those in the control group.The differences were statistically significant(P<0.05).Conclusion The combination of Cr,Er:YSGG laser and gallic acid water extract improved periodontal and oral health,suppressed inflammation,and enhanced clinical outcomes in orthodontic patients with chronic periodontitis.

Abstract:Obesity is a chronic metabolic disease characterized by excessive fat content throughout the body or abnormal accumulation of local fat.Its global prevalence continues to rise and has become a major global public health challenge.Against this backdrop,external treatment methods in traditional Chinese medicine had attracted much attention due to their unique advantages.Among them,cupping therapy has shown potential value in obesity intervention thanks to its simplicity of operation,high safety,and good patient compliance.In recent years,the clinical application of cupping in treating obesity has gradually evolved from the traditional single model to a multi-technology collaborative intervention,and it has been incorporated into the modern evidence-based medical quality management framework.Based on the latest research progress at home and abroad,this study reviews the current situation of cupping therapy for obesity from multiple dimensions including theoretical origin and development,mechanism of action,and clinical practice.The aim is to provide evidence-based basis for optimizing treatment plans and to look forward to future research directions,promoting the standardization and scientific development of this therapy.

Abstract:Objective To explore the influencing factors of elevated serum progesterone(P)levels on the trigger day of the long-acting regimen during the follicular phase in patients with polycystic ovary syndrome(PCOS)and infertility undergoing in vitro fertilization-embryo transfer(IVF-ET).Methods A total of 90 patients with PCOS infertility undergone IVF-ET treatment at Luoyang Central Hospital from January 2023 to October 2024 were selected as the research subjects.All patients were treated with the long-acting long protocol in the follicular phase(triptorelin acetate was injected on the third day of menstruation for down-regulation,and after reaching the target,human menopausal gonadotropin was given for ovulation induction,with regular monitoring and dose adjustment until follicular maturity).Patients were divided into a normal level group and a high level group based on the serum P level on trigger day.The clinical data of the two groups were collected and compared,and the factors with significant differences were included in the multivariate Logistic regression analysis to identify the independent risk factors for elevated serum P on trigger day in PCOS infertility patients undergoing IVF-ET with long-acting long protocol in the follicular phase.Results Among the 90 patients(90 cycles),20 patients(20 cycles)had a serum P level≥1.5 ng·mL-1 on trigger day and were included in the high level group;70 patients(70 cycles)had a serum P level<1.5 ng·mL-1 and were included in the normal level group.The age,total dosage of gonatotropin(Gn),serum estrogen(E2)level,and the proportion of body mass index<24 kg·m-2 in the high level group were all higher than those in the normal level group,and the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that older age,body mass index<24 kg·m-2,higher total Gn dosage,and higher serum E2 level were independent risk factors for elevated serum P on trigger day in PCOS infertility patients undergoing IVF-ET with long-acting long protocol in the follicular phase(OR>1,P<0.05).Conclusion Older age,body mass index<24 kg·m-2,higher total Gn dosage,and higher serum E2 level are risk factors for elevated serum P on trigger day in PCOS infertility patients undergoing IVF-ET with long-acting long protocol in the follicular phase.

Abstract:Objective To explore the effect of the communication-listening-empathy-support multi-dimensional nursing model on negative emotions and self-care ability of elderly patients undergoing cataract surgery.Methods A total of 328 elderly patients who underwent phacoemulsification for cataract at the department of ophthalmology of Kaifeng Central Hospital from June 2021 to February 2025 were selected as the research subjects and randomly divided into a control group and an observation group,with 164 cases in each group.Patients in the control group received routine nursing care,while those in the observation group received the communication-listening-empathy-support multi-dimensional nursing model in addition to the routine care.The negative emotions before and after surgery,self-care ability before and after intervention,quality of life on the first day of hospitalization and three months after surgery,and nursing satisfaction were compared between two groups.Results Seven days and three months after surgery,the scores of the self-rating anxiety scale(SAS)and self-rating depression scale(SDS)in both groups were lower than those before surgery,and the scores in the observation group were lower than those in the control group,with statistically significant differences(P<0.05).After the intervention,the scores of the exercise of self-care agency scale(ESCA)in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).Three months after surgery,the scores of the low vision quality of life questionnaire(LVQOL)in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).The total satisfaction rate of nursing in the observation group was higher than that in the control group,with a statistically significant difference(P<0.05).Conclusion The communication-listening-empathy-support multi-dimensional nursing model can effectively improve the negative emotions of elderly patients undergoing cataract surgery,enhance their self-care ability,improve the quality of life of low vision patients,and increase patient satisfaction with nursing care.