Prediction of Coronary Artery Lesions in Children with Kawasaki Disease by Serum 25-(OH)D3,YKL40,NT-proBNP and sST2Abstract:Objective:To explore and analyze the predictive value of serum 25-hydroxy vitamin D3[25-(OH)D3],human chitinase protein-40(YKL40),N-terminal pro-B-type natriuretic peptide(NT-proBNP),and Soluble growth stimulation expressed gene 2(sST2)for the risk of coronary artery lesions in children with Kawasaki disease.Method:Clinical data of 42 children with Kawasaki disease(designated as the study group)admitted to Suzhou Wujiang Children's Hospital between October 2022 and September 2024,and 45 healthy children(designated as the control group)who underwent routine physical examinations during the same period,were retrospectively analyzed.Based on the echocardiography results of the study group,they were further divided into a coronary artery lesion group(18 cases)and a non-coronary artery lesion group(24 cases).Serum markers were compared between the study group and the control group to assess their value in predicting the risk of coronary artery lesions.Result:Serum 25-(OH)D3 levels in the study group were lower than those in the control group,while YKL-40,NT-proBNP,and sST2 levels were significantly higher(P<0.05).Within the study group,the coronary artery lesion subgroup exhibited higher serum levels of YKL-40,NT-proBNP,and sST2,and lower levels of 25-(OH)D3 compared to the non-coronary artery lesion subgroup(P<0.05).Serum 25-(OH)D3 level showed a negative correlation with the presence of coronary artery lesions(P<0.05),whereas YKL-40,NT-proBNP,and sST2 levels showed positive correlations(P<0.05).The areas under the curve(AUCs)for predicting coronary artery lesion risk were 0.921 for 25-(OH)D3,0.931 for YKL-40,0.745 for NT-proBNP,and 0.963 for sST2.Conclusion:The levels of serum 25-(OH)D3,YKL40,NT-proBNP,and sST2 are closely related to coronary artery lesions in children with KD.Combined detection is helpful for the early clinical identification of high-risk populations of coronary artery lesions in children with KD.
Research Progress on Perimenopausal Syndrome after Endocrine Therapy for Breast Cancer in both Traditional Chinese and Western MedicineAbstract:Endocrine therapy for breast cancer is an important treatment for hormone receptor-positive patients,but it easily induces perimenopausal-like syndrome,leading to hot flashes,night sweats,insomnia,mood swings,etc.,which seriously affect the patients'quality of life.This article reviews the pathogenesis,clinical manifestations of this syndrome,as well as the current status and progress of integrated traditional Chinese and Western medicine treatment,explores its potential in improving symptoms and enhancing quality of life,and provides a reference for clinical practice.
The Effect of Combination Therapy of Dienogest and Laparoscopic Surgery for Infertility Caused by EndometriosisAbstract:Objective:To analyze the clinical efficacy of the combination of dienogest and laparoscopic surgery in the treatment of endometriosis patients.Method:Sixty patients with endometriosis diagnosed and treated in the Xiamen Chang Gung Hospital between February 2022 and February 2023 were included as the subjects.The groups were designed according to the envelope method and named based on different treatment plans.The control group(n=30)was treated with leuprorelin acetate microspheres after laparoscopic surgery,while the observation group(n=30)was treated with dienogest after laparoscopic surgery.The effects of the two treatment regimens,the recovery of endometriosis symptoms,oxidative stress indicators,endometrial receptivity indicators were compared,and the differences in pregnancy conditions within one year were analyzed.Result:Both groups showed significantly shortened ovulation and menstrual recovery times(P<0.05).After treatment,serum malondialdehyde(MDA)and superoxide dismutase(SOD)levels in the observation group were significantly lower than those in the control group(P<0.05).Postoperative endometrial volume,endometrial thickness,and uterine artery resistance were all significantly reduced in the observation group(P<0.05).After one year of follow-up,the natural pregnancy rate and recurrence rate in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:Infertility patients with endometriosis who undergo laparoscopic minimally invasive surgery can improve their symptoms,oxidative stress status,and endometrial receptivity for a longer period of time with the addition of dienogest medication after surgery.This provides a good foundation for smooth pregnancy and can better control the risk of disease recurrence.
Efficacy of Paclitaxel-Coated Balloon in the Treatment of Diabetic Long-Segment Occlusion of the Inferior Knee ArteryAbstract:Objective:To study the efficacy and safety of paclitaxel drug-coated balloons(DCB)in the treatment of long-segment occlusion of the inferior knee artery in diabetes.Method:44 patients with type 2 diabetes mellitus and long-segment occlusion of the inferior knee artery admitted to Mindong Hospital Affiliated to Fujian Medical University from August 2022 to August 2024 were selected as the research subjects.They were divided into the observation group(DCB group)and the control group(PTA group)based on whether drug-coated balloons(DCB)were used during the operation.Among them,21 patients(28 affected limbs)received DCB treatment,and 23 patients(32 affected limbs)received percutaneous transluminal angioplasty(PTA)+stent angioplasty.The Trans-Atlantic Inter-Society Consensus(TASC)Ⅱ classification C and D types.The intraoperative treatment parameters were recorded.The lumen stenosis rates,the postoperative clinical efficacy and the exercise capacity of the two groups before and after the operation were compared.Result:There was no statistically significant difference in the average target lesion vascular length between the observation group and the control group(P>0.05).The primary patency rate of the observation group at 6 months and 12 months was higher than that of the control group,and the difference was statistically significant(P<0.05).The observation group was superior to the control group in terms of motor ability comparison,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the operation time,dilation pressure,dilation time and contrast agent dosage between the two groups(P>0.05).No deaths occurred during the follow-up period in both the observation group and the control group.Conclusion:The drug-coated balloon dilation and shaping group has a better effect on target vessel revascularization in long segment occlusion of the inferior knee artery in diabetes,and the clinical efficacy is good.
The Improvement Effect of the Application of the Interactive Goal-Reaching Nursing Model on the Self-Efficacy of Patients Undergoing Thyroidectomy and the Overall Nursing OutcomeAbstract:Objective:To explore the effect of interactive standard-reaching nursing intervention for patients undergoing thyroidectomy and the improvement of patients'self-efficacy.Method:A total of 103 patients who underwent thyroidectomy and were admitted to the Shaowu Municipal Hospital from January to December 2024 were retrospectively included as the main research subjects.They were divided into two groups based on different intervention methods.One group was the control group(receiving conventional nursing intervention,51 cases),and the other group was the observation group(receiving interactive target achievement nursing intervention,52 cases).The changes in self-efficacy,thyroid function,and quality of life of the two groups were compared.Result:After the intervention,the scores of various self-efficacy scales(CDSES)and the quality of life-100 scale(WHOQOL-100)in the observation group were higher than those in the control group in terms of thyroid stimulating hormone(TSH),parathyroid hormone(PTH)levels,while the levels of free thyroxine(FT4)and free triiodothyronine(FT3)were lower than those in the control group.The differences were statistically significant(P<0.05).Conclusion:For patients with thyroid diseases who undergo thyroidectomy,the implementation of interactive standard care intervention is beneficial for the recovery of their thyroid function,and can also enhance their self-efficacy and quality of life.
Advances in Traditional Chinese and Western Medicine Treatment after Endometrial PolypectomyAbstract:By reviewing and summarizing the relevant literature on the treatment of endometrial polyps(EPs)in recent years,a systematic review of the latest treatment approaches after endometrial polyp resection is conducted,with the aim of providing reference for clinical application.
Effects of Remimazolam Besylate on Postoperative Pain and Serum Inflammatory Markers in Patients with Femoral Neck FractureAbstract:Objective:To investigate the effects of remimazolam besylate on postoperative pain and serum inflammatory markers in patients with femoral neck fracture(FNF).Method:98 FNF patients admitted to the QianDongNanZhou Hospital of Traditional Chinese Medicine between April 2023 and April 2025 were selected and divided into a control group and an observation group according to the random number table method,with 49 patients in each group.The control group received propofol for anesthesia maintenance,while the observation group received remimazolam besylate.Pain intensity at rest and during passive movement was assessed using the Numerical Rating Scale(NRS)immediately after extubation(T0),and at 2 h(T1),4 h(T2),8 h(T3),12 h(T4),24 h(T5),and 48 h(T6)postoperatively.Opioid consumption during 0~24 h and 24~48 h post-surgery was recorded.Blood samples were collected preoperatively at T0,6 h post-surgery,T5,and T6 to measure interleukin-6(IL-6)and C-reactive protein(CRP)levels.Postoperative safety was monitored,and time to first ambulation and hospital stay were recorded.Result:The observation group showed significantly lower NRS scores at T1~T6 under both conditions compared to the control group,with statistically significant differences(P<0.05).Opioid consumption during 0~24 h and 24~48 h,time to first ambulation,and hospital stay were significantly lower in the observation group,with statistically significant differences(P<0.05).IL-6 and CRP levels at 6 h post-surgery,T5,and T6 were also significantly lower in the observation group,with statistically significant differences(P<0.05).Conclusion:Remimazolam besylate alleviates postoperative pain,reduces opioid consumption,and promotes recovery in FNF patients.Its mechanism may be associated with the suppression of inflammatory responses.
The Impact of Perma Mode under Root Cause Analysis on Postoperative Coping Strategies,Spiritual Health and Complications of Colorectal Cancer PatientsAbstract:Objective:To explore the impact of the Positive Emotions Engagement Interpersonal Relationships Meaning Achievement(PERMA)model under root cause analysis on postoperative coping strategies,spiritual health and complications in colorectal cancer patients.Method:120 colorectal cancer surgery patients admitted to Rudong County People's Hospital in Jiangsu Province from May 2023 to May 2025 were randomly divided into a control group(60 cases,receiving routine care)and an observation group(60 cases,receiving PERMA mode intervention under root cause analysis)using a random number table method.The coping strategies,spiritual health,and incidence of complications between the two groups were compared.Result:After the intervention,the observation group exhibited superior coping styles and spiritual health scores compared to the control group,with a lower incidence of complications,showing statistically significant differences(P<0.05).Conclusion:The PERMA model based on root cause analysis can optimize postoperative coping strategies for colorectal cancer patients,improve their spiritual health,and reduce the incidence of complications.
The Therapeutic Effect of Modified Banxia Xiexin Decoction Combined with Quadruple Therapy on Helicobacter Pylori Infected Peptic UlcersAbstract:Objective:To investigate the therapeutic effect of modified Banxia Xiexin Decoction on digestive ulcer combined with helicacter pylori infection,and to explore its efficacy and improvement of inflammatory factors.Method:A total of 86 patients with helicobacter pylori infected peptic ulcer treated in the Beijing First Traditional Chinese Medicine and Western Medicine Hospital from January 2022 to January 2024.They were divided into groups according to the treatment methods,the treatment group patients were treated Banxia Xiexin Decoction combined with a quadruple therapy,and the control group was treated with western medicine,follow up for half a year after treatment.The positive rate of 13C breath and test clinical symptoms of the two groups of patients before and after 2,4 and 6 weeks of treatment were compared.The recurrence of Helicobacter pylori infection and ulcer,detect interleukin were compared between the two groups.The incidence of adverse reactions and the total effective rate of patients after treatment were compared between the two groups.Result:The helicobacter pylori positive rate in the treatment group was lower than that in the control group after 4 and 6 weeks of treatment,and the difference was statistically significant(P<0.05).After treatment,the symptom scores for abdominal pain,upper abdominal bloating,acid reflux,and belching in the treatment group were lower than those in the control group,and the differences were statistically differences(P<0.05).Within six months,the rates of Helicobacter pylori reinfection and ulcer recurrence in the treatment group were lower than those in the control group,and the differences were statistically differences(P<0.05).The levels of interleukin-6,interleukin-8,and high-sensitivity C-reactive protein in the treatment group were lower than those in the control group after treatment.During the treatment period,the incidence of adverse reactions in the treatment group was lower than that in the control group,and the difference was statistically significant(P<0.05).The total effective rate of treatment in the treatment group was higher than the control group,and the difference was statistically significant(P<0.05).Conclusion:Banxia Xiexin Decoction combined with modified prescription can significantly improve the clinical symptoms patients,improve the levels of inflammatory factors,reduce the reinfection rate of Helicobacter pylori and the recurrence rate of ulcer,and improve the clinical efficacy.
The Application of Airway Management Team Intervention in Mechanically Ventilated Patients with Pulmonary InfectionAbstract:Objective:To explore the effect of airway management team intervention in patients with pulmonary infection undergoing mechanical ventilation.Method:A total of 80 patients with pulmonary infection who were admitted to the Yunan County Second People's Hospital and received mechanical ventilation from July 2024 to June 2025 were selected and randomly grouped by the table method,with 40 cases in each group.The control group received routine care,and the study group received airway management.The mechanical ventilation,hospital stay,weaning success rate,arterial blood gas changes,complications,and satisfaction with airway humidification were observed and compared.Result:The study group had shorter mechanical ventilation and hospitalization periods,higher success rate of weaning from the ventilator,and higher satisfaction with airway humidification,and the differences were statistically significant(P<0.05).The study group had lower pH values,arterial blood carbon dioxide partial pressure(PCO2),oxygenation index(OI),and a lower incidence of complications,with statistically significant differences(P<0.05).Conclusion:When mechanical ventilation is applied to patients with pulmonary infection,the intervention of the airway management team can shorten the mechanical ventilation and hospital stay,increase the success rate of weaning from the ventilator and the satisfaction with airway humidification,make the blood gas indicators more ideal,and have fewer complications.
Clinical Value of Jinlida Granules Combined with Metformin in the Treatment of Type 2 Diabetes Mellitus with Deficiency of Both Qi and YinAbstract:Objective:To assess the therapeutic efficacy of Jinlida granules in combination with metformin for managing type 2 diabetes mellitus characterized by concurrent qi and yin deficiencies.Method:The clinical data of 130 patients with type 2 diabetes mellitus with deficiency of both qi and yin admitted to Xiamen Xinglin Hospital from January 2023 to December 2024 were retrospectively collected.According to the previous treatment plan,they were divided into treatment group(n=65)and control group(n=65).The patients in the control group were treated with metformin hydrochloride tablets,and the patients in the treatment group were treated with metformin combined with Jinlida granules.Before and after 12 weeks of treatment,data on fasting blood glucose(FBG),2-hour postprandial blood glucose(PBG),glycosylated hemoglobin(HbA1c)levels,and Traditional Chinese Medicine(TCM)syndrome scores were collected via the electronic medical record system.The therapeutic effects and adverse reactions of the two groups were retrospectively analyzed.Result:After 12 weeks of treatment,the levels of FBG,PBG and HbA1c as well as the TCM syndrome scores in both groups decreased compared to those before treatment.Furthermore,the treatment group exhibited lower values compared to the control group,with statistically significant differences(P<0.05).The overall treatment efficacy rate was significantly higher in the treatment group than in the control group,with a statistically significant difference(P<0.05).When comparing the incidence of adverse reactions between the two groups,no statistically significant difference was observed,with a statistically significant difference(P>0.05).Conclusions:Jinlida granule combined with metformin can reduce the blood glucose level of patients with type 2 diabetes mellitus with deficiency of both qi and yin,improve the TCM symptoms of patients,and improve the therapeutic effect.
Application Effect of Focus on Solution(SFA)Strategy Based on Psychological Analysis Orientation in Patients Undergoing Laparoscopic Total Hysterectomy for Uterine FibroidsAbstract:Objective:The purpose of this research is to explore the application effect of psychoanalysis-based solution-focused approach(SFA)in patients with uterine fibroids undergoing laparoscopic total hysterectomy(LTH).Method:A total of 70 patients diagnosed with uterine fibroids who were hospitalized in Affiliated Mindong Hospital of Fujian Medical University from January to December 2023 were enrolled in this study.They were randomly assigned to two groups with 35 cases each:the control group received routine perioperative nursing,while the intervention group was given SFA strategy intervention guided by psychological analysis.The two groups were compared in terms of negative emotional status,cognitive function,postoperative hospital stay,complication rate,pain degree,and quality of life.Result:Following the intervention,the study group exhibited significantly lower scores on the Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS),and Visual Analogue Scale(VAS)for pain compared with the control group.In contrast,the study group achieved markedly higher scores on the Montreal Cognitive Assessment(MoCA)and the 36-Item Short Form Health Survey(SF-36).All aforementioned differences were statistically significant(P<0.05).Additionally,the postoperative length of hospital stay in the study group was shorter than that in the control group,with a statistically significant difference(P<0.05).Conclusion:Psychoanalysis-based SFA intervention can effectively mitigate anxiety and depression in patients with uterine fibroids undergoing laparoscopic total hysterectomy,enhance their cognitive function,promote postoperative recovery,and remarkably improve their quality of life,thus holding important clinical application significance.
The Effect of Intraoperative Management of Residual Hernia Sac on Perioperative Outcomes and Complications in Patients with Inguinal Oblique Hernia Undergoing TAPPAbstract:Objective:To explore the influence of different treatment methods of residual hernia sac on patients with indirect inguinal hernia in transabdominal preperitoneal hernia repair(TAPP).Method:92 patients with indirect inguinal hernia admitted to Guilin Women’s and Children’s Hospital from January 2022 to December 2024 were randomly divided into improvement group(46 cases)and control group(46 cases)by envelope method.The control group underwent hernial sac dissection,while the improvement group received modified stump hernial sac management.The perioperative indicators,postoperative pain,malondialdehyde(MDA)levels,superoxide dismutase(SOD)levels,total antioxidant capacity(TAC)levels,and incidence of complications were compared between the two groups.Result:The ambulation time and hospitalization time in the improvement group were shorter than those in the control group,and the postoperative VAS score and MDA level were lower than those in the control group,while the SOD and TAC levels were higher than those in the control group,with statistically significant differences(P<0.05).There were no significant differences in complications between the two groups(P>0.05).Conclusion:The modified stump hernial sac management technique used in TAPP surgery for inguinal oblique hernia patients effectively shortens time to ambulation and hospital stay,reduces postoperative pain,and improves postoperative oxidative stress indicators,demonstrating safety and feasibility.
Effect of Combination Therapy with Sevelamer Carbonate,Lanthanum Carbonate and Hemodialysis on Calcium-Phosphorus Metabolism and Renal Function in Chronic Renal Failure PatientsAbstract:Objective:To investigate the influence of sevelamer carbonate,lanthanum carbonate complicated by hemodialysis on calcium-phosphorus metabolism and renal function in chronic renal failure(CRF)patients.Method:A total of 106 CRF patients admitted to the Seventh People's Hospital of Yancheng from March 2023 to March 2025 were randomly assigned using a random number table to two groups with 53 cases in each group.The control group received hemodialysis combined with lanthanum carbonate therapy,while the observation group additionally received sevelamer carbonate on the basis of control group.Clinical efficacy,calcium-phosphorus metabolism,renal function,and adverse reactions were compared between the two groups.Results:Compared with the control group,the total effective rate and serum calcium(Ca)levels were higher in the observation group after treatment,while serum phosphorus(P),blood urea nitrogen,and serum creatinine levels were lower,with statistically significant differences(P<0.05).The comparison of the rate of adverse reactions in both groups expressed no statistical difference(P>0.05).Conclusion:The efficacy of sevelamer carbonate combined with lanthanum carbonate and hemodialysis in treating CRF is well-established.This combination modulates calcium and phosphorus metabolism,improves renal function,and demonstrates favorable safety.
Application Analysis of Empathetic Nursing Based on Narrative Medicine on Postoperative Patients with Ovarian CancerAbstract:Objective:To explore the clinical effect of using narrative medicine based empathetic nursing model in postoperative ovarian cancer patients.Method:120 ovarian cancer patients who underwent surgical treatment admitted at Jinan Integrated Traditional Chinese and Western Medicine Hospital from March 2023 to September 2024.They were randomly divided into a control group and an observation group,with 60 patients in each group.The control group only received routine postoperative nursing measures,while the observation group received empathetic nursing measures based on narrative medicine.The postoperative recovery-related indicators,psychological state,cancer-related fatigue symptoms,and nursing satisfaction were compared between the two groups.Result:The recovery time of bowel sounds,the time of first rectal exhaust and defecation,the healing time of the incision,and the hospital stay in the observation group were all shorter than those in the control group,the satisfaction with nursing was higher in the observation group compared to the control group,and the differences were statistically significant(P<0.05).Before the intervention,both groups had anxiety,depression,feelings of stigma,and symptoms of cancer-related fatigue.There were no statistically significant differences in psychological scores such as the Self-Rating Anxiety Scale(SAS),the Self-Rating Depression Scale(SDS),the Perceived Stigma and Discrimination Scale(PDD),and the Cancer Fatigue Scale(CFS)between the two groups(P>0.05).After the intervention,the above-mentioned scores of the two groups decreased,the above-mentioned scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion:The application of the empathetic nursing model based on narrative medicine in the postoperative patients with ovarian cancer is beneficial to their postoperative recovery,accelerates the recovery process,and significantly improves the patients'negative emotions related to the disease and fatigue symptoms,greatly enhancing their satisfaction with the nursing care.
The Effectiveness of Focused Solution-Oriented Psychological Care in the Perioperative Period for Patients with Hypertensive Intracerebral HemorrhageAbstract:Objective:To evaluate the effectiveness of psychological care based on the Focused Solution Model during the perioperative period for patients with hypertensive intracerebral hemorrhage.Method:Using a random double-color ball method,88 patients with hypertensive intracerebral hemorrhage admitted to Gaochun People's Hospital in Nanjing from June 2021 to November 2024 were divided into a control group(44 cases,receiving conventional nursing)and an observation group(44 cases,receiving psychological nursing based on the Focused Solution Model).The nursing outcomes of the two groups were compared.Result:The Symptom Checklist-90(SCL-90),the Global Assessment of Symptoms(GAS),and the Global Quality of Life-74(GQOLI-74)scores were higher than those in the control group,while blood pressure levels,Hamilton Anxiety Scale(HAMA)scores,and Hamilton Depression Scale(HAMD)scores were lower than those in the control group,with statistically significant differences(P<0.05).Conclusion:The application of psychological care based on the Focused Solution Model demonstrates favorable outcomes during the perioperative period for patients with hypertensive intracerebral hemorrhage.This approach effectively reduces blood pressure levels,alleviates negative emotions,and enhances quality of life.
The Effect of PEWS-Based Tiered Care Model on Blood Gas Parameters and Clinical Recovery in Children with Severe PneumoniaAbstract:Objective:To explore the practical value of a graded nursing model based on Early Warning in Children(PEWS)scoring guidance in the care of children with severe pneumonia,and to provide evidence-based support for improving clinical nursing plans for children with severe pneumonia and enhancing the quality of specialized nursing.Method:80 children with severe pneumonia admitted to Putian First Hospital from April 2023 to April 2025 were randomly divided into two groups,with 40 cases in each group.The control group received routine nursing care,while the observation group received graded nursing care based on PEWS score.Both groups received nursing care until discharge.The blood gas indicators,recovery status,incidence of complications,and comfort level were compared between the two groups.Result:After nursing,the arterial oxygen partial pressure(PaO2)and arterial oxygen saturation(SaO2)in the observation group were lower than those in the control group,while the arterial carbon dioxide partial pressure(PaCO2)and Kolcaba Comfort Scale(GCQ)scores were higher than those in the control group,and the differences were statistically significant(P<0.05).The duration of cough,shortness of breath,high fever,and hospitalization time in the observation group were shorter than those in the control group,and the incidence of complications was less than that in the control group,with statistical significance(P<0.05).Conclusion:The graded nursing model guided by PEWS scoring can accurately evaluate the condition of children with severe pneumonia.By implementing personalized nursing interventions,it can effectively improve the blood gas indicators of children,reduce complications,accelerate disease recovery,and improve their comfort,providing a scientific and efficient new path for the nursing of children with severe pneumonia.
Comparative Efficacy of Methylprednisolone and Dexamethasone in the Clinical Treatment of Anaphylactic Shock Caused by Ant BitesAbstract:Objective:To investigate the comparative efficacy of methylprednisolone and dexamethasone in the clinical treatment of anaphylactic shock caused by ant bites.Method:A retrospective analysis was conducted on 52 patients with anaphylactic shock due to ant bites admitted to Waisha Community Hospital in Longhu District,Shantou City,from April 2022 to May 2025.Based on different treatment medications,patients were divided into a control group and an observation group,each comprising 26 cases.All enrolled patients received standardized emergency treatment for anaphylactic shock.The control group received dexamethasone therapy,while the observation group received methylprednisolone as the intervention.Clinical efficacy,recovery time of clinical symptoms,urine output levels within 5 hours,and adverse reaction incidence rates were compared between the two groups.Result:The observation group demonstrated superior clinical efficacy compared to the control group,shorter time to clinical symptom resolution,higher urine output within 5 hours,and lower incidence of adverse reactions,with all differences being statistically significant(P<0.05).Conclusion:In the clinical treatment of allergic shock caused by ant-venom bites,methylprednisolone shows superior efficacy compared to dexamethasone.It not only accelerates the speed of symptom relief,but also increases the urine output of patients,and reduces the occurrence of adverse reactions.
Application of Real-Time Adaptive Nutrition Education Combined with Real-Time and Repeated Feedback Mechanism in Patients Undergoing Esophageal Cancer SurgeryAbstract:Objective:To observe the application effect of instant adaptive nutrition education combined with instant and repeated feedback mechanism in patients undergoing esophageal cancer surgery.Method:A total of 94 patients who underwent thoracoscopic esophageal cancer radical surgery in Putian University Affiliated Hospital from March 2022 to March 2025 were selected as the study sample.The group was divided into two groups using the coin toss method,with 47 cases in each group.The control group received the routine nutritional care mode of thoracoscopic esophageal cancer radical surgery.The experimental group received immediate adaptive nutrition education combined with immediate+repeated feedback mechanism intervention.The observation indicators of the two groups after intervention were compared.Result:The results showed that the nutritional knowledge,attitude,and behavior scores of the experimental group were higher than those of the control group,the subjective overall assessment scale(PG-SGA)scores were lower than those of the control group,serum albumin(ALB),hemoglobin(Hb),and transferrin(TRF)were higher than those of the control group,and the complication rate was lower than that of the control group,with statistical significance(P<0.05).Conclusion:The use of real-time adaptive nutrition education combined with real-time and repeated feedback mechanism for intervention in patients undergoing esophageal cancer surgery can improve their nutritional knowledge,attitudes,and behaviors,improve their nutritional status,and reduce the probability of complications.
Analysis of the Effect of Combined Spinal-Epidural Anaesthesia with Ropivacaine Combined with Sufentanil on the Blood Gas Index of the Umbilical Cord Artery in Newborn Babies,and Anaesthesia in Women Undergoing Caesarean DeliveryAbstract:Objective:To investigate the effects of combined Spinal-epidural anaesthesia(CSEA)with ropivacaine and sufentanil on the blood gas index of umbilical cord artery of newborn babies and anaesthesia effect of cesarean section delivery.Method:80 cases of cesarean delivery patients admitted to the Zhejiang Provincial People's Hospital Bijie Hospital from January 2022 to January 2024 were divided into the control group(n=40,ropivacaine CSEA)and the observation group(n=40,combined with sufentanil on the basis of the control group)according to the method of random arrangement table.The anaesthetic effects,haemodynamic indexes,neonatal Apgar scores,umbilical artery blood gas indexes and the incidence of adverse reactions were compared and assessed between the two groups.Result:After anaesthesia,the heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP)and mean arterial pressure(MAP)levels of the observation group were higher than those of the control group,with statistically significant differences(P<0.05).The duration of continuous analgesia in the observation group was longer than that of the control group,and the time of onset of anaesthesia,the time of the plane of painlessness,and the time of the plane of maximal sensory block were shorter than those of the control group,with statistically significant differences(P<0.05).There were no statistically significant differences in the comparison of the rates of neonatal(PaO2),carbon dioxide partial pressure(PaCO2),acid-base(pH),Apgar score and the incidence of adverse reactions(P>0.05).Conclusion:The application of ropivacaine combined with sufentanil CSEA in cesarean section mothers has significant effects,which can maintain the stability of maternal haemodynamics,and does not affect the neonate's umbilical artery blood gas indexes and health status,and has high safety