Clinical study on acupoint application combined with modified banxia xiexin tang for the treatment of postprandial discomfort syndrome with mixed cold and heat typesAbstract:Objective:To explore the therapeutic effect of acupoint application combined with banxia xiexin tang on patients with mixed cold and heat postprandial discomfort syndrome(PDS).Methods:All 80 cases of PDS patients ad-mitted to the hospital from June 2022 to January 2024 were selected and grouped according to the number of consulta-tion,with the odd number as the treatment group and the even number as the control group,each with 40 cases.The control group was treated with western medicine,and on the basis of the control group,the observation group was trea-ted with acupoint plastering combined with banxia xiexin tang,both of which were treated for 4 weeks.The therapeutic effect,TCM syndrome score and adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,there was significient difference(P<0.05).Af-ter treatment,the scores of traditional Chinese medicine symptoms such as bloating,cold and loose stools,bitter and dry mouth,belching,and noisy stomach were all reduced in both groups,and the observation group was lower than the con-trol group,there was significient difference(P<0.05).There was no statistically significant difference in adverse reac-tions between the two groups(P>0.05).Conclusion:Acupoint application combined with modified banxia xiexin tang has a satisfactory therapeutic effect on patients with mixed cold and heat PDS,and can improve clinical symptoms with certain safety.
Therapeutic effect of shugan lidan decoction combined with danning tablet on patients with acute attack of calculous cholecystitis after cholecystectomyAbstract:Objective:To explore the clinical efficacy of shugan lidan decoction combined with danning tablet in the treatment of acute calculous cholecystitis(ACC)patients after laparoscopic cholecystectomy(LC).Methods:A total of 120 patients with ACC who planned to undergo LC in fuzhou hospital of traditional chinese medicine from June 2022 to December 2024 were prospectively selected as the study objects and divided into control group and observation group randomly,each group with 60 patients.The control group was treated with LC operation,anti-infection and acid-base regulation after operation,and the observation group was treated with shugan lidan decoction and danning tablet on the basis of the control group.Compare the clinical efficacy,gastrointestinal function recovery time(postoperative bowel sound recovery,exhaust,defecation and feeding time of the first),levels of inflammatory factors[hypersensitive C-re-active protein(hs-CRP),procalcitonin(PCT)],and function of immunity[immunoglobulin M(IgM),immunoglobulin G(IgG),immunoglobulin A(IgA)]and complication rate of the two groups.Results:The clinical efficacy,IgA,IgG and IgM of the observation group were higher than those of the control group,and the gastrointestinal function recovery time,hs-CRP and PCT levels were lower than those of the control group,there was significient difference(all P<0.05).The incidence rate of postoperative complications in the observation group was less than that in the control group(P<0.05).Conclusion:Shugan lidan decoction combined with danning tablet in the adjuvant treatment after LC in ACC patients has better efficacy,and can reduce the level of inflammation,enhance the immune function of the body,promote the recovery of gastrointestinal function,and has good safety.
The application effect of the conventional nursing combined with comprehensive rehabilitation nursing model in the nursing of stroke patients with hemiplegiaAbstract:Objective:To analyze the effect of the conventional nursing combined with comprehensive rehabilitation nursing model in the nursing of stroke patients with hemiplegia.Methods:Eighty patients with stroke hemiplegia admit-ted to the First Affiliated Hospital of Henan University of Science and Technology from January 2022 to December 2024 were randomly divided into control group and observation group,with 40 patients in each group.The control group was given routine nursing intervention,while the observation group was given comprehensive rehabilitation nursing in-tervention on the basis of the control group.The degree of neurological deficit,self-care ability,hemiplegia muscle strength and quality of life were compared between the two groups.Before and after nursing,the national health re-search stroke scale(NIHSS)was used to evaluate the degree of neurological deficit,the Barthel index scale was used to evaluate the ability of self-care,the handheld muscle strength test scale(MMT)was used to evaluate the hemiplegic muscle strength,and the stroke specialized quality of life scale(SS-QOL)was used to evaluate the quality of life.Re-sults:After treatment,the NIHSS score was lower than that before nursing,and the observation group was lower than the control group.The score of Barthel index was higher than before nursing,and the observation group was higher than the control group,with statistical significance(P<0.05).After nursing,the MMT scores of upper limbs and low-er limbs in the two groups were higher than those before nursing,and the observation group was higher than that in the control group,with statistical significance(P<0.05).The scores of SS-QOL in the two groups after nursing were higher than those before nursing,and the observation group was higher than the control group,with statistical signifi-cance(P<0.05).Conclusion:The combined comprehensive rehabilitation nursing model on the basis of conventional nursing can effectively improve the neurological function of stroke patients with hemiplegia,promote the improvement of hemiplegic muscle strength and living ability of patients,and improve their quality of life.
Correlation analysis of folate metabolism related enzyme genes and Hcy with gestational hypertensionAbstract:Objective:To investigate the correlation between folate metabolism related enzyme genes and homocys-teine(Hey)with gestational hypertension(HDP).Methods:All 340 pregnant women with HDP who received treat-ment in putuo district maternity and infant health hospital were selected as the observation group,and the inclusion pe-riod was from May 2023 to February 2025.During the same period,300 healthy pregnant women were selected as the control group.Baseline data,laboratory indexes and folate metabolism related enzyme genes were compared between the two groups.Results:There was no significant difference in age and body mass index between the two groups(P>0.05).The diastolic blood pressure,systolic blood pressure,Hey,alkaline phosphatase(ALP)and uric acid(UA)in the observa-tion group were higher than those in the control group,the level of placental growth factor(PLGF)was lower than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the levels of aspartate aminotransferase(AST),alanine aminotransferase(ALT),blood urea nitrogen(BUN)and creati-nine(CREA)between the two groups(P>0.05).Spearman analysis showed that Hcy,ALP,UA levels were positively correlated with HDP,while PLGF levels were negatively correlated with HDP.Compared with the control group,the frequency of T alleles in the observation group was significantly higher,and the difference was statistically significant(P<0.05).Conclusion:Folate metabolism related enzyme genes and the levels of Hcy,ALP,UA,and PLGF are signifi-cantly correlated with HDP.
Genetic factors and age analysis of spontaneous abortion based on copy number variation sequencingAbstract:Objective:Chromosome abnormalities of spontaneous abortion products were detected by copy number variation sequencing(CNV-Seq)to explore the relationship between gestational age and the occurrence of chromo-somal abnormalities in embryos,and to provide reference for the clinical value of CNV-Seq technology in elderly pa-tients.Methods:The relevant data of 173 patients with spontaneous abortion who were successfully tested by CNV-Seq in yueyang central hospital from June 2020 to March 2025 were collected,and the results of spontaneous abortion products and patient age were analyzed.Results:The age distribution of patients were from 21 to 43 years old,the aver-age age was(30.69±4.59)years old,the proportion of elderly group(≥35 years old)reached 23.12%(n=40),the de-tection rate of pathogenic/possibly pathogenic copy number variations in the elderly group was 65.00%(26/40)among them,which was much higher than that of younger group(<35 years old)with only 45.11%(60/133)(P<0.05).X chromosome monosomy and chromosomal microdeletions/microduplications are predominantly distributed in the youn-ger age groups,and chromosome aneuploidy were more common in the elderly group.Conclusion:Gestational age signif-icantly affected the detection rate of chromosomal abnormalities in spontaneous abortion products,CNV-Seq is neces-sary for identifying the causes of spontaneous abortion,especially in elderly patients.
The application of two kinds of lithotripsy combined with primary suture in patients with common bile duct stonesAbstract:Objective:To compare the curative effects of two kinds of lithotomy combined with primary suture on common bile duct stones.Methods:From April 2023 to December 2024,89 patients with choledocholithiasis were ran-domly divided into observation group(n=45)and control group(n=44)according to the numerical table method.The observation group was treated with mini-incision lithotripsy combined with primary suture at the junction of common bile duct through cystic duct,while the control group was treated with common bile duct exploration lithotomy com-bined with primary suture.The postoperative recovery,liver function index,stress response and complications of the two groups were compared.Results:The recovery time of gastrointestinal function,extubation time and hospitalization time in the observation group were shorter than those in the control group(P<0.05).Three days after operation,the levels of alanine amino transfer(ALT),aspartate amino transfer(AST)and total bilirubin(TBiL)in the two groups were lower than those before operation,the observation group was lower than the control group,the difference was sta-tistically significant(P<0.05).Three days after operation,the cortisol(Cor),epidephrine(E)and adrenocorticotropic hormone(ACTH)in the two groups were higher than those before operation,but the observation group was lower than that in the control group,with statistical significance(P<0.05).After 3 months follow-up,the incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Compared with the exploration of the common bile duct,microincision and stone removal through the con-fluence of the common bile duct are more conducive to postoperative recovery,with milder stress response and fewer complications in the treatment of patients with common bile duct stones.
Study and effect observation of preoperative localization method of ureteroabdominal wall stoma with total cystectomyAbstract:Objective:To explore the preoperative localization method and application effect of ureteroabdominal wall stoma with total bladder excision.Methods:All 82 bladder cancer patients who underwent elective total cystectomy with uretero—abdominal wall stoma were selected from April 2022 to February 2024,and were divided into the control group(41 cases)and the experimental group(41 cases)according to the method of randomized table.The control group used conventional intraoperative localization,and the experimental group used preoperative localization;the post-operative complications,self-care ability,and the quality of life of the two groups were compared.Results:The inci-dence of complications in the observation group was lower than that in the control group,and the scores of self-care a-bility assessment scale(ESCA)and quality of life scale for ostomy patients(Stoma-QOL)were higher than those in the control group,with statistical significance(P<0.05).Conclusion:The preoperative localization of ureteroabdominal wall stoma for total bladder resection can reduce the incidence of postoperative complications,improve self-care abili-ty,and improve the quality of life of patients.
Analysis of risk factors for poor prognosis in elderly patients with mechanical intestinal obstructionAbstract:Objective:To analyze the related risk factors of poor prognosis in elderly patients with mechanical intes-tinal obstruction.Methods:A total of 60 elderly patients with mechanical intestinal obstruction in Tianjin People's Hos-pital from January 2022 to January 2025 were selected and divided into good prognosis group(n=30 cases)and poor prognosis group(n=30 cases)according to their prognosis.The characteristics and related risk factors of patients be-tween two group were analyzed.Results:Univariate analysis showed that PG-SGA grade,operation duration,history of diabetes,disappearance of bowel sounds,incidence of progressive abdominal pain and body mass index(BMI),C-re-active protein(CRP),procalcitonin(PCT),interleukin-6(IL-6)and neutrophil—to—lymphocyte ratio(NLR)lev-els were the influencing factors of mechanical intestinal obstruction in the elderly(all P<0.05).High PG-SGA grade,high PCT,high IL-6 and high NLR are independent risk factors for poor prognosis in elderly patients with me-chanical intestinal obstruction(P<0.05).Higher BMI in normal range was an independent protective factor(P<0.05).Conclusion:Elevated levels of PG-SGA classification,serum PCT,IL-6,and NLR are associated with poor prog-nosis in elderly patients with mechanical intestinal obstruction,while a higher BMI in normal range has a protective effect.Monitoring these parameters can help assess the extent of inflammatory response and nutritional status in pa-tients,providing a basis for clinical intervention,thereby optimizing treatment strategies and improving the recovery outcomes and quality of life for elderly patients.
Effect of rituximab and lenalidomide maintenance regimen in diffuse large B—cell lymphomaAbstract:Objective:To study the efficacy of rituximab and lenalidomide maintenance regimen in diffuse large B-cell lymphoma(DLBCL).Methods:A total of 60 DLBCL patients with complete remission after chemotherapy admitted to the hospital from January 2023 to September 2024 were studied.They were randomly divided into observation group(n=30)and control group(n=30)according to the sealed envelope lottery method.The control group was treated with rituximab maintenance,the observation group was treated with alidomide on the basis of control group.Both groups were treated for 3 months.The levels of neutrophil/lymphocyte ratio(NLR)and platelet/lymphocyte ratio(PLR),im-mune function,serum inflammatory factors,quality of life,and progression-free survival(PFS)were compared be-tween the two groups.Results:After treatment,the levels of NLR,PLR,CD8+and inflammatory factors in both groups were lower than those before treatment,and those in the observation group were lower than those in the control group(P<0.05).After treatment,the scores of CD4+,CD4+/CD8+and quality of life in the two groups were higher than those before treatment,and the observation group was higher than that in the control group(P<0.05).The proportion of PFS>6 months and>12 months in observation group was slightly higher than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion:Rituximab and lenalidomide maintenance regimen is effective in DLBCL,which can improve the immune function and inflammatory response of patients,and is conducive to the improvement of quality of life.
Narrow band imaging—magnifying endoscopic diagnostic value of gastrointestinal metaplasiaAbstract:Objective:To explore the value of narrow-band imaging magnifying endoscopy(NBI-ME)in the di-agnosis of gastric intestinal metaplasia(GIM).Methods:A total of 251 patients who underwent NBI-ME gastroscopy in traditional chinese medicine hospital of wuhu from January 1,2023 to March 10,2024 were selected.The examination sequence was white light endoscopy first,and then NBI-ME was performed.Under NBI-ME,the light blue crest(LBC)of gastric antrum biggish curvature,gastric antrum minor curvature,gastric angle,gastric body biggish curvature and gastric body minor curvature were recorded respectively,and compared with pathological examination results.Re-sults:The sensitivity of LBC under NBI-ME for diagnosing GIM was 85.29%,the specificity was 86.58%,the posi-tive predictive value was 81.31%,the negative predictive value was 89.58%,the Youden index was 71.87%.The ken-dall's tau-b analysis showed a significant positive correlation between operative link on gastritis assessment based on intestinal metaplasia(OLGIM)stage and LBC endoscopic grading,with a correlation coefficient of 0.729.Conclusion:NBI-ME shows high consistency with pathological histology.NBI-ME can immediately make enterization classifica-tion and make monitoring recommendations.Whether it can completely replace biopsy needs further research.
Application of video feedback teaching combined with virtual simulation experiment immersive course in urology nursing teachingAbstract:Objective:To explore the application effect of video feedback teaching combined with virtual simulation experiments in infiltrating courses in urology nursing teaching.Methods:All 118 intern nursing students from the de-partment of urology in second people's hospital affiliated to three gorges university from January 2021 to January 2024 were selected for a controlled study and randomly divided into an observation group and a control group,with 59 cases in each group,using a random number table method.The control group was video feedback teaching,while the observa-tion group was given video feedback teaching combined with virtual simulation experiments for immersive courses.The examination results,comprehensive ability,nursing quality and total satisfaction of teaching were compared between the two groups.Results:The scores of theoretical knowledge,practical operation,nursing case writing,communication,thinking innovation and learning enthusiasm in the observation group were higher than those in the control group,with statistical significance(P<0.05).There was no significant difference in problem-solving scores between the two groups(P>0.05).The scores of nursing quality and total teaching satisfaction in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:The application of video feedback teaching combined with virtual simulation experiment infiltration based courses in urology nursing teaching can effectively improve the assessment scores and comprehensive abilities of internship nursing students,and also help improve nursing quality with high teaching satisfaction.
Research on risk assessment of polypharmacy and pharmaceutical care for elderly diabetic patientsAbstract:Objective:To screen for potentially inappropriate medication(PIM)in elderly hospitalized patients with diabetes using the American Geriatrics Society 2019 Updated AGS Beers Criteria,analyze PIM incidence,establish a pharmaceutical care pathway,and explore the role of clinical pharmacists in managing polypharmacy.Methods:All 368 elderly patients with diabetes hospitalized in the Endocrinology Department of Ningcheng County Central Hospital,Chifeng City,from February 2022 to August 2023 were enrolled.Patients were stratified into PIM group(n=127)and non-PIM group(n=241)based on the Beers Criteria(2019 edition).For the PIM group,potential risk assessments and pharmaceutical interventions were implemented.The study analyzed characteristics of polypharmacy and PIM dis-tribution in local elderly diabetic patients,comparing therapeutic efficacy,safety,and cost-effectiveness before and af-ter pharmacist interventions to develop a clinical pharmacist-led care pathway.Results:Among 368 enrolled elderly di-abetic patients with polypharmacy,127 cases(36.14%)exhibited PIM,totaling 133 PIM instances.The top five PIM with the highest incidence rate are aspirin as primary prevention of cardiovascular events,long-acting sulfonylureas,sliding dose insulin,proton pump inhibitors,benzodiazepines with short-acting and medium-acting effects.There were statistically significant differences between PIM group and non-PIM group in age,types of diseases and types of drugs used(P<0.05).After the intervention of clinical pharmacists,there was no significant difference in the effective rate,the incidence of adverse reactions and the average hospitalization expenses between the two groups(P>0.05).Conclusion:The incidence of PIM in elderly diabetic inpatients with polypharmacy is high.For patients with multiple chronic diseases and diabetic complications,clinical pharmacists should routinely use the Beers Criteria to screen for PIM and conduct risk assessments,and establish a pharmaceutical care pathway,which can ensure the effectiveness and safety of medications and reduce the economic burden on patients.
Effect of supervised short—term individualized vestibular rehabilitation training on patients with de-compensated recurrent peripheral vertigoAbstract:Objective:To explore the effect of short-term personalized vestibular rehabilitation training under su-pervision in patients with decompensated recurrent peripheral vertigo.Methods:According to the random number table method,116 patients with decompensated recurrent peripheral vertigo who visited the hospital from November 2023 to November 2024 were divided into the control group(58 cases were given fixed vestibular rehabilitation training)and the supervision group(58 cases were given short-term individualized vestibular rehabilitation training under supervi-sion).After 2 months of intervention,the assessment results of the dizziness handicap inventory(DHI),visceral sensi-tivity index(VSI),sensory structure test,activity balance confidence scale(ABC),and hamilton anxiety scale(HAMD)were compared between the two groups.Results:The scores of DHI,VSI and HAMD in the observation group were lower than those in the control group after 1 month and 2 months of intervention,the observation group was lower than the control group,the difference was statistically significant(P<0.05).The score of ABC in the observation group was higher than that in the control group after 1 month and 2 months of intervention,the observation group was higher than the control group,the difference was statistically significant(P<0.05).After the intervention,there were no statisti-cally significant differences in proprioceptive and visual scores between the two groups in the left-right and anterior-posterior directions(P>0.05).After the intervention,the vestibular sensation scores in the left-right and anterior-posterior directions increased in both groups compared to pre-intervention levels,with the observation group showing higher scores than the control group,and the differences were statistically significant(P<0.05).Conclusion:Short-term individualized vestibular rehabilitation training under supervision can effectively improve vestibular function,pro-mote vestibular compensation,relieve anxiety and enhance balance confidence in patients with decompensated recurrent peripheral vertigo.
Effects of psychological intervention combined with early adaptation intervention on self—care ability and adaptation level of rectal stoma patientsAbstract:Objective:To investigate the effect of psychological intervention combined with early adaptation inter-vention on the self-care ability and adaptation level of rectal stoma patients.Methods:All 80 cases of rectal stoma pa-tients admitted to the first people's hospital of fuzhou city from March 2022 to May 2024 were randomly divided into the control group and the observation group.The control group received routine nursing,the observation group received psychological intervention combined with early adaptation intervention on the basis of the control group.The depres-sion,anxiety,self-care ability and adaptability of the two groups were compared.Results:After the intervention,the scores of hamilton depression scale-17(HAMD-17)and hamilton anxiety scale(HAMA)in both groups were lower than those before the intervention,and the difference was statistically significant(P<0.05).After the intervention,the scores of self-care competency assessment scale(ESCA)and ostomy patient adaptation inventory(OAI)in both groups were higher than those before the intervention,and the difference was statistically significant(P<0.05).Con-clusion:Psychological intervention combined with early adaptation intervention can reduce the negative emotions of rec-tal stoma patients and improve their self-care ability and adaptation level.
Effect of traditional Chinese medicine intervention via wet—hot compress on postoperative vertebral function and rehabilitation process in patients with osteoporotic vertebral compression fracturesAbstract:Objective:To investigate the effect of traditional Chinese medicine intervention via wet-hot compress on postoperative vertebral function and rehabilitation process in patients with osteoporotic vertebral compression frac-tures(OVCF).Methods:A total of 118 patients with OVCF who underwent surgical treatment in Wuhu Traditional Chinese Medicine hospital from January 2021 to December 2023 were divided into the observation group and the control group using atable of random numbers,with 59 cases in each group.The control group received routine postoperative rehabilitation intervention,while the observation group received traditional Chinese medicine intervention via wet-hot compress.Traditional Chinese medicine symptom scores,vertebral pain degree,vertebral function,rehabilitation effect-sand complications were compared between the two groups.Results:A month after surgery,traditional Chinese medicine-syndrome scores,current pain intensity scores and oswestry disability index(ODI)scores of the observation group were signifi-cantly lower than those of the control group(P<0.05).Meanwhile,anterior height(AH),posterior height(PH)and AH/PH of fractured vertebral bodies in the observation group were larger compared to the control group(P<0.05).The total incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:Traditional Chinese medicine intervention via wet-hot compress can effectively reduce traditional Chinese medicine syndrome scores of patients undergoing surgery for OVCF,alleviate vertebral pain,improve vertebral func-tion,and promote recovery.
Effect of jinfeng pill combined with drospiroone ethinylestradiol on endometrial repair after induced a-bortionAbstract:Objective:To observe the effect of Jinfeng pill combined with drospiroone ethinylestradiol on endometri-al repair after induced abortion.Methods:According to random number table method,86 patients who underwent in-duced abortion in xiamen changgeng hospital from February 2022 to February 2024 were divided into 2 groups with 43 cases in each group.Induced abortion was performed in both groups.The control group was given drospiroone ethi-nylestradiol after operation.On this basis,the observation group was given jinfeng pill for 8 weeks.Endometrial thick-ness,clinical indexes,sex hormones[luteinizing hormone(LH),progesterone(P),follicle-stimulating hormone(FSH),estradiol(E2)]and adverse reactions were compared between the two groups.Results:There was no significant difference in endometrial thickness between the two groups 1 week and 2 weeks after surgery(P>0.05).The endome-trial thickness of the observation group was higher than that of the control group at 4 and 8 weeks after operation(P<0.05).The duration of vaginal bleeding,the time of uterine rejuvenation and the time of first menstruation in observa-tion group was shorter than that in control group,and the amount of vaginal bleeding was lower than that in control group(P<0.05).After treatment,the levels of sex hormones in both groups were increased,and the observation group was higher than the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Jinfong pill combined with drospiroone ethoestradiol can improve the body sex hormone,promote the repair of endometrial,reduce the amount of vaginal bleeding,shorten the duration of va-ginal bleeding,promote uterine relapse and menstrual relapse in patients after induced abortion.The combined treatment of both has high safety without increasing the risk of adverse reactions.
Development of early warning models for postpartum hemorrhage following cesarean section in parturi-ents with different types of placenta previa using machine learningAbstract:Objective:To develop early warning models utilizing machine learning techniques for assessing the risk of postpartum hemorrhage following cesarean section in parturients with varying types of placenta previa.Methods A prospective selection was made of 77 pregnant women with different types of placenta previa who were admitted to the obstetrics department of ganzhou maternal and child health hospital from January 1,2022 to November 30,2023.These cases were divided into two groups based on the occurrence of massive postpartum hemorrhage:the non-massive post-partum hemorrhage group and the massive postpartum hemorrhage group.Additionally,according to a 7∶3 ratio for the training set and validation set,33 cases of pregnant women with different types of placenta previa admitted from De-cember 1,2023 to October 1,2024,were selected for the validation set.Relevant patient data were collected,and inde-pendent predictors were identified through univariate analysis and multivariate logistic regression analysis.Subsequent-ly,logistic regression,decision tree(DT),and back-propagation neural network(BPNN)models were constructed.The predictive performance of these models was evaluated using the area under the receiver operating characteristic(ROC)curve(AUC)and confusion matrix-related indicators(accuracy,precision,recall,F1 score).External valida-tion was also conducted.Results:Eight independent predictors of postpartum hemorrhage were identified through uni-variate and multivariate logistic regression analyses:gravidity and parity,history of induced abortion,metabolic diseases during pregnancy,history of hysteroscopy,scarred uterus,placenta accreta,placenta adhesion,and type of placenta pre-via.The BPNN model exhibited superior AUC values(0.902,0.892)in both the training and validation sets compared to the Logistic and DT models(0.833,0.820 and 0.884,0.852).The BPNN model also outperformed the Logistic and DT models in terms of confusion matrix-related indicators in both sets.In the BPNN model,the importance ranking of independent influencing factors for massive postpartum hemorrhage in cesarean delivery patients with placenta previa is as follows:type of placenta previa>placenta accreta>placenta adherence>scarred uterus>metabolic diseases during pregnancy>gravidity and parity>history of hysteroscopy surgery>history of induced abortion.Conclusion:The BPNN model demonstrates better performance than the Logistic and DT models in predicting postpartum hemorrhage following cesarean section in parturients with placenta previa,providing improved risk assessment for patients and effectively guiding clinical decision-making.
Analysis of the efficacy of red furnace reinforcement therapy intervention in patients with wind-phlegm blocking collaterals facial paralysisAbstract:Objective:To explore the application effect of red furnace reinforcement therapy in patients with wind-phlegm blocking collaterals facial neuritis.Methods:Sixty patients with wind-phlegm blocking collaterals facial neuri-tis,hospitalized in the neurology department of a tertiary hospital in Guangdong Province from October 2023 to May 2024 were selected,and randomly divided into control group and observation group,with 30 patients in each group.The control group received acupoint injection of mouse nerve growth factor,while the observation group received red furnace reinforcement therapy in addition to the control treatment,once every other day for 30 minutes each time.Before and af-ter the intervention for 2 weeks,the patients in the two groups were evaluated by facial nerve function rating scale(H-B),modified peripheral facial nerve treatment score scale(Portmann)and facial disability index(FDI),and the cura-tive effects of the two groups were compared.Results:After the intervention,the grade of H-B scale in the two groups was better than that before the intervention,and the observation group was better than the control group,with statisti-cal significance(P<0.05).After the intervention,the scores of Portmann scale and physical function in FDI scale in the two groups were higher than those before the intervention,the observation group was higher than the control group,and the difference was statistically significant(P<0.05).After the intervention,the social function score in the FDI scale was lower than that before the intervention,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,with statistical significance(P<0.05).Conclusion:Red furnace reinforcement therapy can effec-tively improve the facial nerve function of patients with wind-phlegm blocking collaterals facial neuritis,reduce psy-chological burden,and improve quality of life.
Effect of seamless care supported by evidence-based medicine on postoperative pain and sleep quality in patients undergoing laparoscopic cholecystectomyAbstract:Objective:To explore the effect of seamless care supported by evidence-based medicine on postopera-tive pain and sleep quality in patients undergoing laparoscopic cholecystectomy.Methods:All 200 patients who under-went laparoscopic cholecystectomy in weng'an county people's hospital from January 2024 to January 2025 were select-ed.All 200 patients who underwent laparoscopic cholecystectomy in weng'an county people's hospital from January 2024 to January 2025 were randomly divided into control group with 100 patients in each group.The control group was given routine nursing,while the observation group was given seamless nursing based on evidence-based medicine on the basis of the control group.Both groups were followed up for 2 weeks.The postoperative recovery,pain,psychologi-cal state,sleep quality and satisfaction of the two groups were compared.Results:The time of getting out of bed,ex-hausting time and hospitalization in the observation group were shorter than those in the control group,and the differ-ence was statistically significant(P<0.05).The postoperative visual analogue scale(VAS),self-rating depression scale(SDS),self-rating anxiety scale(SAS)and pittsburgh sleep quality index(PSQI)in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:The seamless care supported by evidence-based medicine can effectively improve the pain degree and psy-chological state of laparoscopic cholecystectomy patients,promote postoperative recovery,improve sleep quality and nursing satisfaction.
Influencing factors of awake prone position ventilation in patients with acute hypoxic respiratory failureAbstract:Objective:To analyze the influencing factors of awake prone position ventilation in patients with acute hypoxic respiratory failure(AHRF).Methods:A total of 97 AHRF patients from January 2023 to July 2024 who un-derwent awake prone position ventilation at shanxi norman bethune hospital were selected,and divided into the good compliance group(41 cases)and the poor compliance group(56 cases)based on their daily prone ventilation time.Uni-variate analysis and multivariate logistic regression analysis were conducted to dentify the influencing factors of AHRF awake prone ventilation compliance.Results:The age of poor compliance group was older than that of good compliance group,and the proportion of mask oxygen inhalation,failure to change body position in time,moderate/severe pain,low social support and moderate/severe disability of self-care ability was higher than that of good compliance group,with statistical significance(P<0.05).Multivariate Logistic regression analysis showed that failure to change body position in time(OR=4.545),moderate/severe pain(OR=3.467)and low social support(OR=3.636)were the independent influencing factors of poor ventilation compliance in awake prone position of AHRF patients(P<0.05).Conclusion:The compliance of AHRF patients with awake prone position ventilation is related to timely change of position,pain level,and social support.