Implementation of Constraint-Induced Movement Training in Children with Hemiplegic Cerebral Palsy and Its Effects on Motor FunctionAbstract:Objective:To investigate the implementation of forced-induction exercise training in children with hemiplegic cerebral palsy and its effects on their motor function.Methods:A total of 74 pediatric patients diagnosed with hemiplegic cerebral palsy at Kaifeng Children's Hospital between March 2022 and March 2024 were enrolled as study subjects.They were randomly assigned to two groups using a random number table,with 37 patients in each group.The control group received conventional rehabilitation training,while the observation group underwent constraint-induced movement therapy based on the control group's intervention protocol.Muscle tone,fine motor function,brain development,and activities of daily living were compared between the two groups.Results:After intervention,the wrist flexor and elbow flexor scores on the Modified Ashworth Scale(MAS)were lower in the observation group than in the control group,with statistically significant differences(P<0.05).After intervention,the scores on all subscales of the Peabody Developmental Motor Scale(PDMS)(grasping,visual-motor integration,and fine motor quotient)were higher in the observation group than in the control group,with statistically significant differences(P<0.05).After intervention,the scores for all items(posture,social behavior,hearing,and control ability)on the Gesell Developmental Scale(GDS)were higher in the observation group than in the control group,with statistically significant differences(P<0.05).After intervention,the Modified Barthel Index(MBI)scores were higher in the observation group than in the control group,with statistically significant differences(P<0.05).Conclusion:Constraint-induced movement therapy can enhance muscle tone in children with hemiplegic cerebral palsy,improve their fine motor skills,promote brain development,and enhance their activities of daily living.
Application of"CBL+PBGS"Diversified Teaching Model in Undergraduate Clinical Teaching of Rehabilitation TherapyAbstract:Objection:To observe the results and promotion value of the application of case-based learning(CBL)combined with project based group study(PBGS)diversified teaching model in the teaching of rehabilitation internship students.Methods:From July 2023 to August 2024,selecting 60 undergraduates of Rehabilitation Therapy from Class 2019 and Class 2020 who performed rotational internships in the Departments of Rehabilitation,the Affiliated Hospital of Southwest Medical University as study subjects,they were divided into a control group and an experimental group using a random number table method,with 30 cases in each group.The control group corresponding to the regular internship teaching,the observation group corresponding to the"CBL+PBGS"diversified teaching method.Comparing the assessment scores of the theoretical examination,practical operation test and satisfaction survey of rehabilitation internship students.Results:The theoretical knowledge and clinical practical skills scores of the experimental group students were higher than those of the control group;the satisfaction of the experimental group students with teaching was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion:The application of"CBL+PBGS"diversified teaching in undergraduate clinical teaching of rehabilitation therapy is superior to traditional teaching.This model is conducive to improving the rehabilitation professional skills and comprehensive quality of rehabilitation therapy students,thus better adapting to clinical rehabilitation internships.
Application of Combined CBL and PBL Teaching in Clinical Education for Critical Care MedicineAbstract:Objective:To explore the effectiveness of integrating problem-based learning(PBL)with case-based learning(CBL)in critical care medicine education.Methods:A total of 64 clinical medical students who completed their internship in the Department of Critical Care Medicine at Guizhou Medical University Affiliated Hospital from June 2023 to June 2024 were selected as research subjects.They were randomly divided into an experimental group and a control group,with 32 students in each group.The experimental group underwent a combined CBL and PBL teaching model,while the control group received traditional lecture-based learning(LBL).The examination scores,teaching evaluations,and comprehensive quality assessments of the trainees in the experimental and control groups were compared.The impact of the two groups' baseline data on the research findings was analyzed.Results:The examination scores(objective questions and case analysis)and teaching effectiveness evaluations of the trainees in the experimental group were significantly higher than those of the control group in the experiment.In the teachers' comprehensive evaluations of student competencies,the trainees in the experimental group scored higher than the control group in self-directed learning ability,case analysis ability,clinical reasoning ability,teamwork ability,information retrieval ability,report writing ability,and clinical procedural skills,with statistically significant differences(P<0.05).Conclusion:The combined CBL and PBL teaching approach significantly enhances the educational outcomes for intensive care medicine residents.It improves trainees' independent learning abilities,clinical reasoning skills,information retrieval capabilities,and teamwork spirit.This approach holds significant importance for elevating the quality of training for intensive care medicine residents.
Comparative Analysis of Ultrasound Features and TSH,Tg,TgAb,and TPOAb Results Between Micro and Non-Micro Papillary Thyroid CarcinomaAbstract:Objective:To analyze the ultrasound characteristics and serological differences among papillary thyroid carcinomas(PTC)of varying sizes,thereby providing a basis for the diagnosis and treatment of papillary thyroid carcinoma.Methods:A total of 101 patients who underwent thyroidectomy at the First Hospital of Lanzhou University between October 2022 and October 2024 and were pathologically diagnosed with papillary thyroid carcinoma were enrolled in this study.Based on the maximum tumor diameter,they were divided into Group A(micro-papillary thyroid carcinoma,maximum diameter≤1 cm)comprising 60 cases and Group B(maximum diameter>1 cm)comprising 41 cases.The borders,echogenicity,aspect ratio,calcifications,blood flow,capsular invasion,and lymph node metastasis of papillary thyroid carcinoma in two patient groups were analyzed and compared under ultrasound guidance.The results for thyroid-stimulating hormone(TSH),triglycerides(TG),antithyroglobulin antibodies(TGAb),and anti-thyroid peroxidase antibodies(TPOAb)were compared between the two groups.Results:Univariate analysis revealed statistically significant differences between the two groups in terms of margins,echogenicity,aspect ratio,calcification,blood flow,and lymph node metastasis(P<0.05).The differences in TSH,Tg,TgAb,and TPOAb levels between the two groups were not statistically significant(P>0.05).Multivariate analysis revealed that calcification,blood flow,and lymph node metastasis were associated with increased volume in papillary thyroid carcinoma.Conclusion:Micro-and non-micro-papillary thyroid carcinomas exhibit differences in calcification and blood flow,necessitating careful clinical differentiation.Non-micro-papillary thyroid carcinomas demonstrate enhanced lymph node metastasis potential compared to micro-papillary carcinomas,underscoring the importance of early prevention and treatment for papillary thyroid carcinoma.No differences were observed in serum markers between micro-and non-micro-papillary thyroid carcinomas.
The Demand for Smart Elderly Care Services and Influencing Factors among the Elderly in NingxiaAbstract:Objective:To understand the current status of elderly people's demand for smart elderly care services and analyze the influencing factors.Methods:A random sampling method was used to conduct a questionnaire survey among elderly people aged 60 and above in 5 cities of Ningxia.Results:Elderly people had a relatively high willingness for smart elderly care,with safety and health services,medical and health care services,and spiritual comfort services ranking at the top.There were differences in the demand for smart elderly care among elderly people with different characteristics.Conclusion:Elderly people in Ningxia have a relatively high demand for smart elderly care services.It is necessary to gradually improve the construction of smart elderly care resources in Ningxia,establish corresponding platforms,enhance the level of elderly care services,and promote the development of smart elderly care services.
The Therapeutic Effects of Mang Needle Yin Yang Penetration Needling Method Combined with Yiqi Huayu Decoction on Post-Stroke Limb Spasticity and Its Impact on Apoptosis Related IndicatorsAbstract:Objective:To explore the effects of the Mang needle yin-yang penetration method combined with Yiqi Huayu decoction in the treatment of post-stroke limb spasms and its impact on apoptosis related indicators.Methods:A total of 86 patients with post-stroke limb spasticity admitted in the Second People's Hospital of Zhenping County from January 2022 to January 2024 were selected and divided into a study group and a control group using the case number envelope drawing method,with 43 cases in each group.The patients in the control group received routine rehabilitation training,while patients in the study group received the Mang needle yin-yang penetration acupuncture method combined with Yiqi Huayu decoction treatment.The limb function,neurological function,living ability,neurotransmitters,and apoptosis related indicators of the two groups were compared.Results:After treatment,the scores of Fugl-Meyer Assessment Scale(FMA)and Berg Balance Scale(BBS)in the study group were higher than these in the control group,while the Composite Spasticity Scale(CSS)in the study group was lower than that in the control group,and the difference was statistically significant(P<0.001).Compared with the control group,National Institutes of Health Stroke Scale(NIHSS)in the study group was lower,while the Barthel index was higher,and the difference was statistically significant(P<0.001).Compared with the control group,the levels of glycine(Gly)and gamma aminobutyric acid(GABA)in the study group were higher,and the difference was statistically significant(P<0.001).Compared with the control group,the scores of cysteine containing aspartic protease(Caspase-3),fatty acid synthase(Fas),Fas ligand(FasL)in the study group were lower,and the difference was statistically significant(P<0.001).Conclusion:Patients with limb spasticity after stroke can improve limb and nerve function,regulate neurotransmitters,inhibit brain cell apoptosis,and enhance their ability to live by receiving the Mang needle yin-yang penetration acupuncture method combined with Yiqi Huayu decoction.
Effects of Rehabilitation Training Combined with Acupuncture on Intelligence and Language Function of Children with Autism Spectrum DisordersAbstract:Objective:To explore the therapeutic effect of rehabilitation training and acupuncture treatment on the intelligence and language function in children with autism spectrum disorders.Methods:A total of 120 children with autism spectrum disorder admitted to the Fifth Affiliated Hospital of Zhengzhou University in 2023 were selected as the objective,and grouped as the control group and observation group according to the double-blind method(n=60).The control group using rehabilitation training,while the observation group were given acupuncture treatment based on the control group's treatment.The clinical effectiveness,action and ability level,intelligence level,disease severe degree and long-term curative effectiveness were compared.Results:The total clinical efficacy rate of the observation group was higher than that of the control group,and the differences were statistically significant(P<0.05).After treatment,the observation group of children scored higher in all dimensions of psychoeducational profile-Third Edition(PEP-3)compared to the control group,and the differences were statistically significant(P<0.05).After treatment,the observation group scored higher in all dimensions of Gesell scale,and the differences were statistically significant(P<0.05).After treatment,the observation group scored lower in all dimensions of Austion Behavior Checklist(ABC)compared to the control group,and the differences were statistically significant(P<0.05).The difference in Austism Treatment Evaluation Checklist(ATEC)scores between before treatment and after 6 months of treatment in the observation group was(22.63±2.85)points,which was higher than that in the control group(16.08±2.79)points,with a statistically significant difference(P<0.001).Conclusion:The treatment effect of rehabilitation training combined with acupuncture in children with autism spectrum disorder is quite remarkable can improve the clinical efficacy,enhance the intelligence and language functions,and alleviate the autistic behaviors
Application Value of Visualization Health Education Combined with Specialist Nurse-guided Perioperative Respiratory Training Prescription on Patients with Lung Cancer SurgeryAbstract:Objective:To explore the application value of visualization health education combined with specialist nurse-guided perioperative respiratory training prescription on patients undergoing lung cancer surgery.Methods:From June 2020 to June 2023,210 patients receiving lung cancer surgery admitted to Shanghai Pulmonary Hospital were studied.By means of random envelope method,the patients were classified into observation group(105 cases,visualization health education combined with specialist nurse-guided perioperative respiratory training prescription)and control group(105 cases,routine nursing).Negative emotions,exercise tolerance and lung function before intervention and at 6 months after intervention,compliance and nursing satisfaction after intervention and postoperative complications were compared between groups.Results:After intervention,hospital anxiety and depression scale-anxiety(HADS-A)score was decreased in both groups,and the score in observation group was lower(t=6.553,P<0.05).The 6 minites walk test(6MWT),forced vital capacity(FVC),forced expiratory volume in 1 seconds(FEV1),FEV1projected value(FEV1%)in both groups were increased after intervention,and the indexes were higher in observation group(P<0.05).The total compliance rate and total nursing satisfaction in observation group were higher while the incidence of complications was lower(P<0.05).Conclusion:Visualization health education combined with specialist nurse-guided perioperative respiratory training prescription for patients with lung cancer surgery can relieve negative emotions,enhance exercise tolerance and lung function,improve respiratory training compliance and nursing satisfaction,and reduce incidence of complications.
Study on the Impact of Hospital-Acquired Infections on Hospitalization Costs for Acute Leukemia Chemotherapy Patients Using Propensity Score MatchingAbstract:Objective:To explore the direct economic burden incurred by acute leukemia patients undergoing chemotherapy due to hospital-acquired infections.Methods:A total of 496 patients with acute leukemia undergoing chemotherapy admitted to the sample hospital between 2022 and 2023 were selected as study subjects.Among them,78 patients developed hospital-acquired infections(infection group),while 418 patients did not develop such infections(non-infection group).A propensity score matching(PSM)method was employed to achieve a 1:1 match between the two groups.Statistical analysis was conducted on the matched patients' length of hospital stay and hospitalization costs.Results:After PSM-balanced randomization,the median hospital stays for the matched infected and non-infected groups were 25 days and 10 days,respectively,and the total hospital costs were 31 434.89 yuan and 11 826.09 yuan,with statistically significant differences(P<0.05).The costs for consultation fees,Western medicine,treatment,examinations,Chinese herbal medicine,laboratory tests,blood transfusions,bed occupancy,nursing care,and medical supplies were all higher in the infection group than in the non-infection group,with all differences statistically significant(P<0.05).The greatest difference between the two groups was in Western medicine costs(11 383.78 yuan),while the highest ratio was observed in Chinese herbal medicine costs(3.79).Conclusion:Hospital-acquired infections in acute leukemia patients prolong hospitalization and increase medical costs;infection prevention and control measures for these patients should be strengthened.
Observation of the Effect of KAP Health Education Based on Orem Self-Care Theory on Improving Self-Management Capabilities in Patients with Chronic Atrophic GastritisAbstract:Objective:To explore the effectiveness of KAP health education based on Orem Self-Care Theory in enhancing self-management capabilities among patients with chronic atrophic gastritis.Methods:Selecting 106 patients with chronic atrophic gastritis admitted to the Second Affiliated Hospital of Nanhua University from March 2021 to November 2022 as study subjects,they were randomly divided into experimental group(n=53)and reference group(n=53).The reference group received routine nursing care intervention,while the experimental group additionally received KAP health education with Orem self-care theory based on the routine nursing care.The exercise of self-care agency scale(ESCA),general self-efficacy,self-rated abilities for health proutice scale(SRAHP),Pittssburgh sleep qualith index(PSQI)and Connor-Davidson Presilience scale(CD-RISC)of the two patient groups were compared before and after the intervention,along with the incidence of adverse reactions.Results:After the intervention,the ESCA,GSES scores,SRAHP scores,PSQI scores,and psychological resilience scores of the experimental group patients were better(P<0.05).The incidence of adverse reactions in the experimental group patients was lower(P<0.05).Conclusion:Health education based on Orem self-care theory can enhance self-management capabilities,improve health behavior capacity,enhance sleep quality,increase psychological resilience,reduce adverse reactions and recurrence rates among patients with chronic atrophic gastritis.
Efficacy Evaluation and Analysis of Integrated Traditional Chinese and Western Medicine Therapy for Chronic Cough in Children after Mycoplasma Pneumoniae InfectionAbstract:Objective:To explore the therapeutic efficacy of integrated traditional Chinese and Western medicine in treating chronic cough in children following Mycoplasma pneumoniae infection.Methods:A total of 90 children with chronic cough after Mycoplasma pneumoniae infection admitted to Xuchang Beihai Hospital from 2022 to 2024 were randomly divided into a control group and an observation group,with 45 cases in each group.The control group received conventional Western medical treatment,while the observation group was additionally treated with traditional Chinese medicine decoctions and acupuncture therapy.Serum inflammatory cytokine levels,syndrome scores,therapeutic efficacy,and adverse reactions were compared between the two groups before and after treatment.Results:The observation group exhibited a significantly greater reduction in serum inflammatory cytokine levels(IL-6 and IL-10)compared to the control group.The traditional Chinese medicine syndrome scores in the observation group were lower than those in the control group.The clinical effective rate in the observation group was higher than that in the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The integrated traditional Chinese and Western medicine approach can effectively regulate inflammatory responses,improve clinical symptoms and signs,enhance the clinical cure rate in children with chronic cough following Mycoplasma pneumoniae infection,and demonstrates a high level of safety.
Factors Influencing the Development of Aspiration Pneumonia in Elderly Patients with Dysphagia Following Cerebral InfarctionAbstract:Objective:To investigate the prevalence and associated factors of aspiration pneumonia in elderly patients with dysphagia following cerebral infarction.Methods:A total of 172 patients with dysphagia following cerebral infarction in the elderly admitted to Yuzhou People's Hospital between April 2022 and April 2024 were selected as study subjects.Based on systematic medical record documentation of aspiration pneumonia occurrence,they were divided into an occurrence group and(63 caces)a non-occurrence group(109 caces).Relevant data from both groups were collected and compared.For indicators showing differences,collinearity analysis was performed.Indicators without collinearity issues were incorporated into a logistic regression model to analyze factors influencing the occurrence of aspiration pneumonia in patients.Results:According to medical record system data,among 172 elderly patients with dysphagia following cerebral infarction,63 developed aspiration pneumonia,accounting for 36.42%,and were assigned to the occurrence group.The remaining 109 pa-tients did not develop aspiration pneumonia,representing 63.58%,and were assigned to the non-occurrence group.There were statistically significant differences between the two groups in terms of comorbidities,improper positioning,nasogastric feeding,National Institutes of Health Stroke Scale(NIHSS)scores,oral hygiene,C-reactive protein(CRP),neutrophil count,and neutrophil-to-lymphocyte ratio(NLR)(P<0.05).Through collinearity analysis,it was found that nasogastric feeding,NHISS score,oral hygiene,CRP,and NLR did not exhibit collin-earity issues.These indicators could thus be incorporated into the logistic regression model.Logistic regression analysis revealed that all these indicators were risk factors for patients developing aspiration pneumonia.Conclusion:Nasogastric feeding,NHISS score,oral hygiene,CRP,and NLR are all independent risk factors for aspiration pneumonia.These indicators provide a theoretical basis for early clinical prediction,screening of high-risk groups,and implementation of relevant interventions.
Study on the Relationship between the Selection of Internal Fixation Materials and Postoperative Functional Recovery of Ankle FractureAbstract:Objective:To explore the relationship between the selection of internal fixation materials and postoperative functional recovery of ankle fracture and provide individualized fixation scheme for patients.Methods:According to the choice of internal fixation materials,100 patients with ankle fracture in the 988th Hospital of the Joint Service Support Force of the Chinese People's Liberation Army(Jiaozuo Hospital Area)from January 2021 to May 2024 were divided into steel plate group(34 cases),metal screw group(33 cases)and absorbable screw group(33 cases).The basic information of patients and postoperative ankle recovery were collected,including operation time,intraoperative blood loss and hospitalization time,foreign body reaction rate,AOFAS score,fracture healing time,complete load-bearing time and visual analogue scale(VAS).Results:Compared to other groups,there were longer operation time and hospitalization time,and larger intraoperative hemorrhagein in steel plate group,and the differences were statistically significant(P<0.05).The operation time and intraoperative hemorrhagein in the metal screw group and absorbable screw group were compared,here was no significant difference(P>0.05).AOFAS score of absorbable screw group was significantly higher than that of steel plate group and metal screw group,and the steel plate group was higher than that of metal screw group,and the differences were statistically significant(P<0.05).The fracture healing time and complete load-bearing time were significantly lower than those of steel plate group and metal screw group,and steel plate group was shorter than metal screw group,and the differences were statistically significant(P<0.05).The VAS score of absorbable screw group was lower than that of steel plate group and metal screw group,and the metal screw group was lower than that of steel plate group,and the differences were statistically significant(P<0.05).The foreign body reaction of absorbable screw group was significantly shorter than that of steel plate group and metal screw group,and the differences were statistically significant(P<0.05).Conclusion:Different internal fixation materials have obviously different prognosis effects on patients with ankle fracture.Although the foreign body reaction rate of absorbable screw fixation method is obviously higher,its perioperative indicators and joint function recovery are good.When using absorbable screws in clinical treatment,doctors should pay attention to rejection and take relevant preventive and therapeutic measures to further improve the prognosis of patients.
The Structure and Function of MFN2 and Its Role in DiseaseAbstract:Mitofusin 2(MFN2),as a mitochondrial dynamics-related protein,not only mediates mitochondrial fusion and division,but also participates in various pathophysiological processes such as mitochondrial adenosine triphosphate(ATP)supply,mitochondrial endoplasmic reticulum-associated membranes(MAMs),cellular energy metabolism,calcium ion homeostasis,endoplasmic reticulum stress,and autophagy,and plays different roles in different processes.MFN2 plays different roles in different diseases,such as acting as mitochondrial axial transport in Charcot-Marie-Tooth disease type 2A(CMT2A),neuroprotective in Alzheimer's disease,and inhibiting cancer in cancer.A comprehensive review of the structure and function of MFN2 and its role in disease were provided.
Effects of Emotional Stability Traits on Job Adaptation among Physicians in Training:Mediated by Coping StylesAbstract:Objective:To investigate the influence of emotional stability trait on the work adjustment of resident doctors and the mediating role of coping strategies,and to provide evidence for enhancing the work adjustment ability of resident doctors.Paying attention to the work adjustment of resident doctors is not only beneficial to their own development,but also beneficial to the overall improvement of hospital service level.Methods:A random sampling method was used to select 518 trained doctors from a university affiliated hospital in Heilongjiang Province from September 2023 to January 2024 as the research subjects.It explored the relationship among three variables:emotional stability traits,work adaptation,and coping strategies.The study used the Work Adaptation Disorder Scale,Emotional Factors Scale,and Trait Coping Style Scale to conduct an online questionnaire survey of trained doctors,and analyzed the data using SPSS statistical software.Results:Emotional stability was closely related to job adaptation and coping style,and its traits positively predict job adaptation(declarable 41.8%of the variance).Positive coping was positively related to emotional stability,while negative coping was negatively related.Coping style had a mediating effect,with positive mediating effects accounting for-5.90%of the total effect,and negative effects accounting for 18.10%.The direct effect was 87.70%.Conclusion:Coping styles play a partial mediating role in the influence of the trait of emotional stability on the work adaptation of resident physicians in standardized training.The trait of emotional stability can not only directly affect the work adaptation of resident physicians in standardized training,but also indirectly influence work adaptation by affecting individuals' coping styles.
Study on the Influence of Intervention Models for Tendency,Reinforcement,and Facilitating Factors on the Rehabilitation of Chronic Obstructive Pulmonary DiseaseAbstract:Objective:The impact of the tendency,reinforcement,and facilitating factors(PRECEDE)intervention model on the rehabilitation status of patients with chronic obstructive pulmonary disease(COPD).Methods:A total of 110 COPD patients admitted to our hospital from January 2022 to October 2023.A computer-generated random sequence was used and assigned to a control group(55 cases)and an experimental group(55 cases).The control group received routine clinical intervention,while the experimental group received PRECEDE intervention management.After the intervention,a one-year follow-up was conducted to compare the health cognition level,compliance behavior score,adverse prognosis,and lung function recovery of the two groups of patients.Results:Under different intervention modes,the experimental group scored higher than the conventional group in terms of COPD pathology knowledge,current treatment status,precautions during treatment,and personal management points,with statistically significant differences(t=3.102,3.318,3.668,3.056;P<0.05).The compliance behavior scores of the experimental group in terms of daily routine management,scheduled medication,active rehabilitation,and regular follow-up were higher than those of the control group,with statistically significant differences(t=3.241,3.333,3.326,3.164;P<0.05).During the follow-up period,the incidence of poor prognosis in the experimental group was lower than that in the control group,with statistically significant differences(x2=6.253;P<0.05).As of the end of follow-up,the first second forced expiratory volume percentage(FEV1),forced vital capacity(FVC),peak expiratory flow rate(PEF),6-minute walk test(6MWT)in the experimental group were all higher than those in the control group,with statistically significant differences(t=2.575,6.407,3.858,3.707;P<0.05).Conclusion:The PRECEDE intervention model can improve the health cognition level and compliance behavior of COPD patients,and has a positive significance in reducing the risk of adverse prognosis and promoting lung function recovery.
Anaysis on the Curative Effects of Interpersonal Relationship Development Intervention Therapy Combined with Language Training in the Treatment among Children with AutismAbstract:Objective:To explore the effect of interpersonal relationship development intervention(RDI)combined with language training in the treatment of children with autism.Methods:A total of 75 children with autism admitted to Pingxiang Maternal and Child Health Care Hospital from September 2022 to January 2024 were selected as the research objects.According to different intervention methods,they were divided into RDI group(n=25,adopted RDI),language training group(n=24,adopted language training)and observation group(n=26,adopted RDI combined with language training).The children's Psychoeducational Inventory for Autism(PEP-3)score,Family Adaptability and Cohesion Scale(FACESII-CV,Chinese version)score,and social ability[Autism Children's Social Skills Rating Scale(ASSS)]score were observed and compared among the three groups before and after intervention.Results:After intervention,the scores of the four dimensions of PEP-3 scale,the scores of each dimension of ASSS scale,the scores of cohesion and adaptability of the three groups all increased,and the observation group had the highest score,followed by the language training group,and the RDI group had the lowest score,with statistically significant differences(P<0.05).Conclusion:Compared with RDI alone or language training alone,RDI combined with language training is more effective in children with autism and can significantly improve the children's clinical symptoms,social skills,family cohesion and adaptability.
Study on the Therapeutic Effect of Tripterygium Wilfordii Polyglycoside Combined with Daggligin in Patients with Diabetes NephropathyAbstract:Objective:To study the therapeutic effect of the combined use of Tripterygium wilfordii polyglycosides and dapagliflozin in patients with diabetic nephropathy(DN).Methods:A total of 105 patients with diabetic nephropathy(DN)who received treatment at Luohe Central Hospital from 2022 to 2024 were selected as the subjects and randomly divided into conventional group(52 cases)and combined group(53 cases).The conventional group received treatment with dapagliflozin,while those in the combined group were treated with a combination of Tripterygium wilfordii polyglycosides and dapagliflozin.During the treatment process,renal function-related indicators,blood glucose metabolism-related indicators,and the occurrence of adverse reactions in both groups of patients were carefully observed and meticulously recorded.Results:After treatment,renal function improved in both groups,with more significant improvement observed in the combined group,and the differences were statistically signficant(P<0.05).The levels of blood glucose in the combined group were lower than those in the conventional group,and the differences were statistically signficant(P<0.05).The incidence of complications in the combined group was significantly lower than that in the conventional group,and the differences were statistically signficant(P<0.05).Conclusion:The combined use of Tripterygium wilfordii polyglycosides and dapagliflozin can significantly optimize renal function and blood glucose metabolism-related indicators in patients with diabetic nephropathy,while effectively reducing the incidence of complications.
Correlation Study on Health Beliefs,Self-Perceived Burden,and Adherence to Rehabilitation Training in COPD Pa-tientsAbstract:Objective:To investigate the status quo of health belief in patients with chronic obstructive pulmonary disease(COPD)and its relationship with compliance in rehabilitation training,and to provide research basis for the design of health belief intervention programs for patients with COPD.Methods:A cross-sectional survey was conducted on 300 COPD patients treated in the respiratory department of a number of first-class hospitals in Jinan City with Champion health belief model scale,self-perceived burden scale and exercise compliance questionnaire.AMOS 22.0 was used to analyze the mediating effect of the data.Results:The total score of health belief(135.52±22.28)points,the total score of self-perceived burden(23.33±4.28)points,the overall score of exercise compliance was low,and the compliance was generally poor.In COPD patients,health belief was negatively correlated with perceived burden,positively correlated with exercise compliance,and negatively correlated with perceived burden and exercise compliance.Conclusion:The health belief of COPD patients in this study was at a high level.Patients'perceived burden was lower,and their perceived economic burden was heavier.The patients generally had poor exercise compliance,and most of them had exercise intensity compliance.The higher the patients'health belief,the weaker their self-perceived burden,and the stronger their exercise compliance.
Correlation Analysis of Ocular Hemodynamics,Blood Glucose Level and Visual Impairment in Diabetes RetinopathyAbstract:Objective:To investigate the correlation between ocular hemodynamics,blood glucose level and visual impairment in diabetes retinopathy(DR).Methods:From September 2021 to June 2024,100 patients with diabetes retinopathy admitted in Puyang Oilfield General Hospital were selected as the research object,and they were set as DR group(165 eyes).Another 100 patients with simple type 2 diabetes without DR were selected as non DR group(169 eyes),and the ocular hemodynamics and blood glucose levels of the two groups were compared.Then 100 DR patients were divided into mild group(n=22,38 eyes),moderate group(n=43,79 eyes),and severe group(n=25,48 eyes)according to the degree of visual impairment of patients.The ocular hemodynamics and blood glucose levels of the three groups were compared,and the correlation between ocular hemodynamics,blood glucose levels and visual impairment of diabetes retinopathy was analyzed.Results:The DR group had higher ocular artery pulsatility index(PI),resistance index(RI),central retinal artery PI,RI,fasting blood glucose,2-hour postprandial blood glucose,and glycosylated hemoglobin than the non DR group.The DR group had lower end diastolic velocity(EDV)and peak systolic velocity(PSV)of the ocular artery,as well as lower central retinal artery EDV and PSV than the non DR group,with statistically significant differences(P<0.05);the PI,RI of the ophthalmic artery,RI of the central retinal artery,fasting blood glucose,and glycosylated hemoglobin were higher in the severe group than in the mild and moderate groups,while the PSV of the ophthalmic artery,EDV,and PSV of the central retinal artery were lower in the severe group than in the mild and moderate groups,with statistically significant differences(P<0.05);the Spearman correlation analysis results showed that the levels of visual impairment in DR patients were positively correlated with ophthalmic artery PI,RI,central retinal artery PI,RI,fasting blood glucose,and glycosylated hemoglobin,the levels of visual impairment in DR patients were negatively correlated with ophthalmic artery PSV,central retinal artery EDV,and PSV,with statistically significant differences(P<0.05).Conclusion:Compared with patients with type 2 diabetes alone,patients with diabetes retinopathy have significant ocular hemodynamic abnormalities and relatively high blood glucose levels,and ocular hemodynamics and blood glucose levels are closely related to the degree of visual impairment in DR patients.