Abstract:OBJECTIVE To analyze the data from free cervical cancer screening for urban and rural women in Shantou,summarize the prevalence of cervical cancer and precancerous lesions,and evaluate the current screening practices.METHODS Following the procedures outlined in the Implementation Plan for Free"Two Cancers"Screening for Urban and Rural Women in Shantou City(2020-2022),basic information was collected and examinations were conducted on eligible women.Case registration forms for cervical cancer screening were completed,and data were entered into the Guangdong Maternal and Child Health Information Platform.RESULTS A total of 76 594 women completed cervical cancer screening from 2020 to 2022.The average detection rate of precancerous lesions was 392.98/105,with annual rates of 255.47/105,461.31/105,and 461.46/105.The average detection rate of cervical cancer was 37.86/105,with annual rates of 19.65/105,44.64/105,and 49.44/105.Statistical differences were observed in the detection rates of precancerous lesions and cervical cancer across years(x2=22.98,7.66,P＜0.05).Key quality indicators included an average early diagnosis rate of 93.03％,a treatment follow-up rate of 70.15％,a colposcopy completion rate of 76.80％,and a histopathological examination rate of 103.42％.CONCLUSION The detection rate of cervical cancer among urban and rural women in Shantou is relatively high,shows an increasing trend annually,and identifies a high proportion of CIN2-3 and carcinoma in situ.

Abstract:OBJECTIVE To analyze the epidemiological characteristics of imported malaria outbreaks in Suzhou from 2015 to 2024,and provide a basis for formulating strategies and measures to prevent the retransmission of malaria.METHODS Using descriptive epidemiological methods to analyze the prevalence and distribution characteristics of imported malaria in Suzhou from 2015 to 2024.RESULTS After Suzhou reached the standard for eliminating malaria in 2015,the 128 reported cases of malaria from 2015 to 2024 were all imported cases from abroad,with no reported deaths.There were case reports in all months of the city,with no obvious seasonal characteristics.The top three regions in terms of reported incidence are Zhangjiagang city,Xiangcheng district and Gusu district of Suzhou city.The disease occurs in the age group under 65 years old,with the highest reported incidence in the age group of 25 to 54 years old,with a male to female ratio of 24.6∶1.The population is mainly composed of workers,farmers,household and unemployed individuals,commercial services.CONCLUSION Suzhou should continue to strengthen the prevention and control for imported malaria,ensuring that malaria cases can be detected,diagnosed,and treated early,preventing the re transmission of malaria,and continuously consolidating the achievements of elimination.

Abstract:OBJECTIVE To analyze the prevalence of depressive symptoms and associated influencing factors among mid-dle-aged and elderly patients with comorbid hypertension,diabetes,and dyslipidemia("three high").METHODS Utilizing data from the fifth wave(2020)of the China Health and Retirement Longitudinal Study(CHARLS),it selected participants aged≥45 years concurrently diagnosed with hypertension,diabetes,and dyslipidemia.The prevalence rate of depressive symptoms was calcu-lated,and multivariate logistic regression analysis was employed to identify independent risk factors.RESULTS A total of 751 eligi-ble participants were included,with a depressive symptom prevalence rate of 46.07％.The results of multi-factor logistic regression analysis showed that living in rural areas and having limitations in activities of daily living were risk factors for depression.Sleep du-ration ≥6 hours,being male,and having a high self-rated health status were protective factors against depression.CONCLUSION The detection rate of depression in middle-aged and elderly patients with comorbid"three highs"in China is relatively high.It is necessary to strengthen the assessment of depressive symptoms in this group,focusing on middle-aged and elderly patients with"three highs"comorbidities in rural areas,short sleep time and impaired ability to live,and taking targeted measures to ensure their mental health.

Abstract:OBJECTIVE To understand the epidemiological characteristics of HIV/AIDS cases aged 60 and above reported in Suzhou,provide data support for formulating and adjusting prevention,control,and screening strategies.METHODS The newly cases reported HIV/AIDS aged 60 and above of Suzhou from 2019 to 2024 were collected from China Information System for Disease Control and Prevention.The cross-sectional survey method was used to investigate.RESULTS From 2019 to 2024,there were 771 HIV/AIDS newly cases aged 60 or above which were reported in Suzhou,accounting for 18.0％in the whole population,which showed an upward trend(x2=32.9,P＜0.05).The gender ratio was 4.8∶1,mainly in the age group of 60～69 years(64.2％).The educational level was mainly primary school or below of these cases.The mainly transmission route was heterosexual transmission(81.5％),male population were primarily engaged in non-marital commercial activities(76.4％),while female were mainly involved in non-marital and non-commercial relationships(57.1％).Most HIV/AIDS cases had low CD4 levels,and the number of CD4＞500/μL was 10.6％.59.8％of cases was detected passively,through hospital preoperative,there were 126 cases of death,61.1％of death cases survival time was less than one year.The differences of disease name,gender,marital status,educational level,transmission rout,the first CD4 result and sample source aged under 60 years old were all statistically significant(P＜0.05).CONCLUSION The mainly epidemiological characteristics of HIV/AIDS cases aged 60 and above in Suzhou is male-dominated,low education level,heterosexual transmission,passively detection and short survival time.Epidemiological characteristics differed from those aged under 60 years.It is necessary to identify effective tools and platforms for education and awareness campaigns to enhance safety and testing awareness among this population.To definite the source of infection and provide precise prevention and control measures.

Abstract:OBJECTIVE To analyze the development of nursing-related research on young and middle-aged cancer patients,with the aim of providing a basis for future studies in this area.METHODS Using CiteSpace 6.3.R1 software,this study examined publications on nursing research related to young and middle-aged cancer patients from January 2005 to December 2024 in the Web of Science Core Collection.The analysis focused on publication volume,authors,countries,institutions,and keywords.RESULTS The annual number of publications on nursing research for young and middle-aged cancer patients had shown a fluctuating upward trend.However,connections and collaborations among authors,institutions,and countries remained weak.Research hotspots mainly included patients' psychological state,quality of life,financial toxicity,social support,decision-making,and physical symptoms.CONCLUSION Increasing attention is being paid to young and middle-aged cancer patients in the field of nursing research.It is recommended that future studies strengthen collaboration among authors,institutions,and countries to jointly explore effective methods for alleviating physical symptoms,improving psychological resilience,providing social support,and facilitating informed decision-making.These efforts aim to improve patients' quality of life and support their return to normal life and work.

Abstract:OBJECTIVE To understand the prevalence of common diseases among students in a street in Qingpu District of Shanghai,and control of common diseases among students.METHODS From 2019 to 2023,6 628 students at 4 national monitoring schools in a street of Qingpu District were selected to monitor common diseases.The x2 test was used to compare the detection rates of common diseases among primary and secondary school students in different grades,genders,and years.RESULTS From 2019 to 2023,the detection rates of common diseases among students in a street in Qingpu District,from high to low,were as follows:low vision(77.55％),dental caries(27.05％),obesity(17.44％),malnutrition(8.57％),and abnormal spinal curvature(1.03％).The overall detection rate of low vision among students in different stages was highest in high schools(88.97％),while the detection rates of malnutrition and overweight were highest in vocational schools(19.50％,13.97％)The detection rates of obesity and dental caries were highest in primary schools(21.60％,36.36％).Abnormal spinal curvature was maintained at a high level in junior high schools,high schools,and vocational schools;the detection rates of low vision and dental caries in girls(78.58％,28.34％)were higher than those in boys(76.62％,25.88％),and the detection rates of overweight and obesity in boys(20.34％,21.83％)were higher than those in girls(13.16％,12.58％).The detection rates of low vision and dental caries were the highest in 2020(83.14％,35.67％),the detection rate of malnutrition was the highest in 2019(10.12％),and the detection rates of obesity and abnormal spinal curvature were the highest in 2022(29.90％,1.98％).CONCLUSION The detection rates of common diseases such as poor eyesight,dental caries and obesity among primary and secondary school students in a certain street of Qingpu District are relatively high.Targeted intervention activities should be carried out as soon as possible to further strengthen the prevention and treatment of common diseases among students and gradually reverse the increasing trend of the prevalence of common diseases among students.

Abstract:OBJECTIVE To understand the current status of routine immune delay and leakage of the acellular pertussis combined vaccine(DTaP)for Newborn children in Chengguan District of Lanzhou and analyze the influencing factors of delayed vaccination of DTaP.It will provide data support for formulating strategies to improve timely vaccination of DTaP.METHODS The vaccination records of children born from 2021 to 2023 were collected through the comprehensive platform for disease prevention and control management in Gansu Province.The delayed vaccination rate of 1～3 doses of vaccine and the leakage rate of DTaP 2 and DTaP 3 were analyzed.The x2 test was used to compare the regional differences in delayed vaccination of pertussis vaccine at 1 dose,2 dose,and 3 dose,and the delayed vaccination and leakage situation of pertussis vaccine were statistically analyzed by region.The total proportion of delayed DTaP 1,DTaP 2,and DTaP 3 in children born in Chengguan District of Lanzhou from 2021 to 2023 was 22.90％,52.46％,and 69.24％,respectively.Among them,the proportion of delayed DTaP 1,DTaP 2,and DTaP 3 in the eastern region was higher than that in the western region in 2021 and 2023,and the difference was statistically significant(P＜0.05).The total leakage rates of DTaP 2 and DTaP 3 were 2.39％and 6.27％,respectively.The total leakage rates of DTaP2 and DTaP3 were higher in the eastern region than in the western region,and the difference was statistically significant(P＜0.05).CONCLUSION The proportion of delayed vaccination of DTaP 2 and DTaP 3 among eligible children in Chengguan District of Lanzhou is relatively high and there is a certain degree of leakage,especially in the eastern region.Further analysis is needed to identify the reasons for the imbalance of vaccination services between the eastern and western regions,change service concepts,improve the level of children's vaccination services,and avoid delayed and missed vaccination.

Abstract:OBJECTIVE To analyze the intention of middle school students in a health promotion school in a certain urban area of Hangzhou to use cigarettes and E-cigarettes and its influencing factors,so as to provide a theoretical basis for the prevention of adolescent smoking.METHODS Through multi-stage stratified sampling,1 677 students were selected from the health promotion schools in a main urban area of Hangzhou in September 2021.The Global Youth Tobacco Survey(China)questionnaire was used to collect information such as the basic situation of students,the intention to use either cigarettes or e-cigarettes,and second-hand smoke exposure.A multi-factor logistic regression model was used to analyze the influencing factors of tobacco use intention.RESULTS Among 1 476 students who had never tried smoking cigarettes or E-cigarettes,128(8.67％)had the intention to smoke,of which 54(3.66％)had the intention to use cigarettes,and 101(6.84％)had the intention to use E-cigarettes.The results of multi-factor logistic regression analysis showed that male gender,exposure to tobacco advertisements,friends not smoking,and receiving education on the harm of tobacco in class were the influencing factors for the smoking intention of junior high school students in a certain urban area of Hangzhou in the coming year.CONCLUSION The overall intention of middle school students in a certain urban area of Hangzhou to use tobacco is relatively low,but the intention to use E-cigarettes is higher than that of cigarettes.The roles of peer,school and family education are extremely important.In order to effectively reduce the future tobacco use intention of middle school students,it is necessary to strengthen the publicity and education on the harm of tobacco and create a smoke-free social environment.

Abstract:OBJECTIVE To analyze the health examination results of the elderly who aged at 60 or above in Qingpu District of Shanghai in 2024,to provide the basis for the health management of the elderly to the goverment.METHODS The physical examination results of 123 993 aged at 60 or above in Qingpu District in 2024 were statistically analyzed.RESULTS The main abnormal results of physical examination in the elderly above 60 years old in Qingpu District were lung nodule(68.98％),central obesity(68.45％),dyslipidemia(61.96％),abnormal electrocardiogram(51.97％),confirmed hypertension(49.23％),fatty liver(46.38％),overweight(38.77％).Pulmonary nodules,abnormal electrocardiogram,confirmed hypertension and overweight were significantly higher in males than in females(x2=216.429,201.053,11.937,321.635,P＜0.05).The rate of central obesity,dyslipidemia and fatty liver in females were higher than those in males,and the difference was statistically significant(x2=816.767,2 041.689,10.838,P＜0.05).The time point blood pressure control rate of hypertension patients was 45.48％,and the time point fasting blood glucose control rate of diabetes patients was 39.36％.The proportion of the elderly with ≥ 1 chronic disease was 90.72％,the proportion with ≥2 chronic diseases was 69.82％,and the proportion with ≥3 chronic diseases was 45.52％.CONCLUSION In 2024,the elderly ≥60 years old in Qingpu District have high prevalence of chronic diseases,prominent comorbidity problems,and low control rate of blood pressure and fasting blood glucose.Comprehensive intervention measures should be taken to achieve common prevention,management and treatment of chronic diseases in the elderly.

Abstract:OBJECTIVE To understand status and the effect factors related to life quality assessment of HIV/AIDS patients who are under the community follow-up management mode in Changning District of Shanghai.METHODS Conducted a one-to-one ques-tionnaire survey on HIV/AIDS patients who received follow-up management from community health service centres from October to December in 2023.RESULTS A total of 370 subjects were investigated in the study,with an average age of(40.96±1 1.52)years;345 were males(93.24％);majority of the interviewees(245,66.22％)had been diagnosed for more than 5 years;the total score of social support was(27.74±9.08),which was lower than the normal level;74.86％(277)subjects were satisfied with the commu-nity follow-up services;the average score for the physiological and psychological area of the respondents' quality of life score was(55.25±5.94),and(48.98±10.34),respectively.Through multiple linear regression analysis,it was found that complaints of discom-fort,social support,and satisfaction with community follow-up within six months had a certain impact on the physiological and psy-chological area of quality of life,and the differences were statistically significant(P＜0.05).In addition,the average monthly in-come and comorbidity of multiple diseases were also factors that affect the physiological area score of quality of life,and the diffe-rence was statistically significant(P＜0.05).CONCLUSION The quality of life of HIV/AIDS patients under the community follow-up management mode in Changning District is acceptable.In the future,it should further enrich the connotation of community fol-low-up management,strengthen symptom monitoring and treatment,further reflect the social support and bridging role of communi-ty health service centres for HIV/AIDS patients,enhance the flexibility of community follow-up,to promote the long-term quality of life of patients.

Abstract:OBJECTIVE To analyze the pathogen spectrum characteristics of respiratory and intestinal syndrome in Tianshui,and provide a basis for the precise prevention and control of bacterial infectious diseases.METHODS The laboratory test data of 816 sentinel surveillance cases(400 respiratory cases,416 diarrhea cases)in First People's Hospital of Tianshui from 2022 to 2023 were collected and analyzed epidemiologically.RESULTS A total of 816 cases were collected from the pathogen identification network of China in the study.The overall positive rate of respiratory syndrome was 8.3％(33/400),with Klebsiella pneumoniae(10 cases,30.3％)being the predominant pathogen.There was a statistically significant difference in the positive rate of respiratory syndrome among different years(x2=5.582,P＜0.05),with the positive rate in 2022(5.8％)being significantly higher than that in 2023(2.5％).The overall positive rate of diarrhea syndrome was 5.9％(23/416),with diarrheagenic Escherichia coli(12 cases,52.2％)being the main pathogen.There was a statistically significant difference in the positive rate of diarrhea syndrome among different age groups(x2=4.381,P＜0.05),with the positive rate in children under 5 years old(4.3％)being significantly higher than that in the≥5-year-old group(1.2％).CONCLUSION In Tianshui,key prevention and control should be carried out for Klebsiella pneumoniae respiratory tract infections and diarrheal Escherichia coli diarrhea in children.It is recommended to optimize the specimen collection process and strengthen the monitoring of foodborne diseases.

Abstract:OBJECTIVE To understand the etiology and epidemiological characteristics of foodborne diseases in Jiangbei District of Ningbo,analyze the incidence trends of foodborne diseases,and provide a basis for preventing foodborne diseases and ensuring food safety.METHODS Descriptive statistical analysis was conducted using active foodborne disease surveillance data from Jiangbei District of Ningbo from 2019 to 2024.RESULTS A total of 2 675 foodborne disease cases were detected from 2019 to 2024.The positive pathogen detection rate was 17.94％,primarily dominated by Norovirus and Vibrio parahaemolyticus.Norovirus had the highest detection rate at 12.71％,followed by Vibrio parahaemolyticus at 4.60％.The detection rates of pathogens varied significantly across different seasons(P＜0.05),with Norovirus peaking in winter and spring,and bacterial infections peaking in summer and autumn.The affected age groups were mainly young and middle-aged individuals aged 18～34 and 35～59 years,with no statistically significant difference in positive rates between genders.High-risk occupational groups included office workers,laborers/farmers,and homemakers/unemployed individuals.The primary suspected exposure food category was aquatic animals and their products(23.33％),and the main consumption locations were households and food service establishments.CONCLUSION Norovirus and Vibrio parahaemolyticus are the main pathogens causing foodborne diarrhea in Jiangbei District.Targeted food safety education should be directed at young and middle-aged individuals engaged in physical labor,and hygiene management in food service establishments should be strengthened.

Abstract:With the aging of the population,a variety of chronic physical diseases are in-creasingly common among the elderly.Chronic physical diseases not only seriously affect the physical health of the elderly,but also are closely related to the occurrence and development of depression.It explores the definition of comorbidity,depression,epidemiological characteristics,correlation mechanisms,factors of influence,diagnostic assessment,and intervention strategies.Studies have found that chronic somatic diseases are bidirectional associated with depression,involving biological,psychological and social factors.Effective screening tools and comprehensive intervention strategies are essential to improve outcomes in elderly patients.Through comprehensive analysis of existing studies,it aimsto provide scientific basis and clinical guidance for the prevention and treatment of comorbid chronic somatic diseases in the elderly.Future studies should focus on individualized interventions and long-term follow-up to improve the quality of life in the elderly population.

Abstract:OBJECTIVE To analyze the epidemiological characteristics of public health emergencies in Chengyang District from 2014 to 2024,so as to understand the rules of public health emergencies and provide evidence for improving the precise prevention and control capabilities of public health emergencies.METHODS Data of public health emergencies in Chengyang District from 2014 to 2024 was collected and conducted statistical analysis to explore epidemiological characteristics based on occurrence time,event types,occurrence place,and timeliness.RESULTS From 2014 to 2024,there were a total of 417 public health emergencies with 1 564 cases,and the peak months were December,November,and February,in that order.Public health emergencies were mainly infectious diseases,with 186 cases,accounting for 44.60％.Households,communities/villages,catering service places were the high incidence places of public health emergencies,with 170 cases,78 cases,and 63 cases,respectively.The timeliness analysis found that the timeliness of the report of public health emergencies from 2014 to 2024 was 0.85(0.17～12.38)hours.CONCLUSION It should strengthen the monitoring and management of public health emergencies during peak months,and increase attention and sensitivity to infectious diseases that need to be prevented controlled.It should also carry out publicity and education of public health emergencies in key prevention and control places such as households,communities/villages,catering service places,in order to enhance the ability to scientifically and effectively respond to public health emergencies.

Abstract:OBJECTIVE To analyze the effect of medical science popularization on enhancing the infectious disease health literacy of junior high school students and provide a reference for health science popularization in school.METHODS A stratified cluster random sampling approach was employed to recruit 263 students from the seventh to ninth grades at Fuyang Experimental Middle School between September in 2023 and May in 2024.A baseline survey on infectious disease health literacy was then carried out.Subsequently,a team of medical science popularization instructors was established.Taking into account the seasonal characteristics of infectious disease prevalence,timely science popularization presentations and on-site interactive sessions were organized,targeting the knowledge areas where students had relatively weak understanding.Each event was restricted to 40 minutes.The study aimed to compare the levels of change in students' infectious disease health literacy before and after the intervention.RESULTS The proportions of students who obtained health information from the Internet were 39.8％,63.9％,and 57.6％,while those who obtained it from other sources were 17.0％,3.6％,and 6.5％.The accuracy rate of responses on infectious disease health literacy showed that basic knowledge and concepts(68.9％,73.5％,71.3％),prevention(63.6％,73.3％,72.4％)were higher than management and treatment(42.3％,58.1％,51.9％)and identification of infection sources(44.9％,46.4％,48.4％).The correct answer rates of grade 7 students for eight items such as hepatitis B,influenza,epidemic water and HIV were all below 50％.The infectious disease health literacy scores of students in the three grades showed that they were higher after the intervention than before.The Cohen's d values of the four dimensions were between 0.66 and 0.88,and the effect sizes of the total scores were all greater than 1.CONCLUSION Junior high school students have limited access to health information.The medical science popularization activities in combination with baseline surveys could enhance the health literacy level of students regarding infectious diseases.

Abstract:OBJECTIVE To analyze the detection rate of hyperuricemia and its related risk factors among people aged 45 and above who underwent health check-ups in Sijing Community of Songjiang district of Shanghai in 2024,so as to provide a basis for the prevention and treatment of hyperuricemia in the region.METHODS The health check-up data of residents aged 45 and above in Sijing Community of Shanghai in 2024 were collected.The prevalence of hyperuricemia and the correlations between hyperuricemia and factors such as gender,age,blood lipids,and liver function were analyzed.RESULTS Among 13 162 residents who underwent health checkups,1 948 had hyperuricemia,with a detection rate of 14.80％.The detection rate in men was 23.77％,and in women,it was 7.52％.The detection rate of hyperuricemia in men was significantly higher than that in women.The detection rate of hyperuricemia and the average value of blood uric acid in women increased with age.The average value of blood uric acid and the detection rate of hyperuricemia in men were the highest in the 45～55 age group.The levels of triglycerides,low-density lipoprotein,creatinine,total bilirubin,urea nitrogen,hemoglobin,and alanine aminotransferase in the hyperuricemia group were significantly higher than those in the normal blood uric acid group,while the level of high-density lipoprotein was lower than that in the normal blood uric acid group.CONCLUSION The detection rate of hyperuricemia is higher in men than in women.In women,the detection rate of hyperuricemia and the average value of blood uric acid increase continuously with age.Hyperuricemia is closely related to many factors such as blood lipids and liver function.Communities should attach importance to the prevention and treatment of hyperuricemia and advocate a healthy lifestyle,which is conducive to reducing the blood uric acid level.

Abstract:OBJECTIVE To understand the prevalence of pulmonary tuberculosis and its influencing factors among the elderly in the community,and to assess the awareness rate of core tuberculosis knowledge,so as to provide a basis for optimizing prevention and control strategies.METHODS A cross-sectional survey design was adopted.From May to July in 2024,total of 1 041 communi-ty-dwelling elderly people aged 60 and above of Shanghai were subjected to chest X-ray examination,questionnaire survey and laboratory tests(IGRA,tongue swab).The questionnaire used the standardized tool of the three-year action plan for the construc-tion of the public health system in Shanghai.RESULTS One case of active pulmonary tuberculosis was detected(detection rate 96.15/105),and the abnormal rate of chest X-ray was 34.77％(362/1 041),among which 9 cases were suspected of tuberculosis(0.86％).The total awareness rate of core tuberculosis prevention knowledge was 87.90％,and the lowest awareness item was"pul-monary tuberculosis is a serious chronic infectious disease"(84.53％).There were statistically significant differences in patients whose chest X-ray abnormalities with male gender,advanced age,low BMI,and history of diabetes was higher(x2=19.069,28.560,23.527,115.071,P＜0.05).CONCLUSION It is recommended to apply tongue swab testing and AI film reading technolo-gy in the screening process,strengthen the key monitoring of high-risk group,and innovate health education forms.

Abstract:OBJECTIVE To investigate the iodine nutrition status of pregnant women in Weifang and provide a basis for scientific iodine supplementation and prevention of iodine deficiency disorders(IDD).METHODS Monitoring data from IDD surveys in Weifang(2017-2024)were collected,and the iodine content in household salt and urinary iodine levels of pregnant women were analyzed.A database was established using Excel,and statistical analysis was performed using SPSS 13.0.RESULTS A total of 9 099 urine samples from pregnant women were collected from 2017 to 2024,with a median urinary iodine level of 156.3 μg/L.Comparisons of median urinary iodine levels among different years and regions showed statistically significant differences(x2=225.196,267.384;P＜0.05).Additionally,it collected salt samples from households with pregnant women totaling 9 600;among these,there were 8 568 qualified iodized salts,while there were also 427 unqualified iodized salts and 605 non-iodized saltsresulting in a non-iodized salt rate of 6.3％,an iodized salt coverage rate of 93.70％,an iodized salt qualification rateof 89.25％,and a qualified iodized salt consumption rateof 95.25％.The comparison of iodized salt qualification rates across different years revealed statistically significant differences(x2=216.62,P＜0.05).The median urinary iodine levels for pregnant women consuming qualified versus unqualified iodized salts were 157.18 μg/L and 146.00 μg/L respectively,and the difference was statistically signi ficant(x2=12.607,P＜0.05).Pregnant women's median urinary iodine level was highest in northern coastal areas at 176.45 μg/L and lowestin southern hilly areas at 148.04 μg/L with statistical significance observed when comparing different topographical regions(x2=170.598,P＜0.05).Urinary iodine levels during late pregnancy were found to be lowest at 152.40 μg/L,and comparisons among various stages showed statistically significant differences(x2=12.514,P＜0.05).CONCLUSION The iodine nutrition status of pregnant women in Weifang is generally adequate.However,some years and regions still fail to meet the IDD elimination criteria.Public health efforts should strengthen awareness campaigns on the importance of iodized salt and guide pregnant women in proper iodine supplementation.

Abstract:OBJECTIVE To analyze the current status of hyperuricemia(HUA)among individuals aged 18 to 60 undergoing health check-ups and its correlation with kidney function in a certain hospital.METHODS A total of 33 112 individuals aged 18 to 60 who had health check-ups at Zhengzhou Central Hospital from 2021 to 2023 were selected.General information and laboratory data were collected.The distribution status of HUA was analyzed to identify factors affecting HUA and its correlation.RESULTS The prevalence of HUA among the health check-up population aged 18 to 60 was 21.93％,with a trend of younger men(x2=367.40,P＜0.01);the prevalence across all age groups was higher in men than in women(P＜0.01).Logistic regression indicated that eGFR,body mass index(BMI),diastolic blood pressure(DBP),blood urea nitrogen(BUN),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),fasting blood glucose(FBG),and glycated hemoglobin(HbA1c)were influencing factors for HUA(P＜0.05).Grouping by eGFR＜90 ml·min-1·(1.73 m2)-1 and eGFR≥90 mL·min-1·(1.73 m2)-1 showed that there was a difference in HUA prevalence between the two groups(x2=422.847,P＜0.01);after adjusting for confounding factors,the risk of eGFR＜90 mL·min-1·(1.73 m2)-1 in the HUA group was 2.11 times that of the normal uric acid group(95％CI:1.936～2.299,P＜0.01).CONCLUSION Among individuals aged 18 to 60 undergoing health check-ups in a certain hospital of Zhengzhou,there is a trend of younger males experiencing HUA,with a prevalence higher than that of females;abnormalities in eGFR,BMI,DBP,BUN,TG,HDL-C,LDL-C,FBG,and HbA1c all increase the risk of HUA;HUA is an independent risk factor for abnormal kidney function.

Abstract:OBJECTIVE To quantify the strength of association between sleep duration and stroke risk,and to elucidate the moderating effects of gender,urban-rural setting,and chronic diseases,thereby informing the formulation and refinement of public health policies.METHODS Utilising data from the China Health and Retirement Longitudinal Study,it included 19 350 middle-aged and older adults aged 45 years and above.A multi-model stratified analysis was employed to examine the association between sleep duration and stroke risk,along with its potential mechanisms.RESULTS Abnormal sleep duration(either insufficient or excessive)constitutes a significant modifiable risk factor for cardiovascular and cerebrovascular diseases.Both insufficient sleep time(＜6 hours)and excessive sleep time(＞8 hours)substantially elevate stroke risk,with the association exhibiting marked heterogeneity across gender,residential location,and chronic disease subgroups.CONCLUSION Both insufficient sleep time(＜6 hours)and excessive sleep time(＞8 hours)substantially elevate stroke risk among middle-aged and elderly Chinese individuals.Risk heterogeneity is pronounced,with males,rural residents,and those with chronic diseases constituting stroke high-risk groups.Potential biological mechanisms include metabolic dysregulation,inflammatory activation,and blood pressure fluctuations.Tailored interventions addressing population-specific characteristics are warranted to mitigate stroke risk in this demographic.