Abstract:Objective This study aimed to investigate the effects of gradient-controlled oxygen therapy on oxidative stress markers and anemia-related parameters in patients undergoing maintenance hemodialysis(MHD),to provide evidence-based support for optimizing clinical care protocols.Methods Using prospective randomized controlled trial design,the research included 100 maintenance hemodialysis(MHD)patients treated at the Nephrology Department of Guizhou Provincial People's Hospital between December 2023 and December 2024.Patients were randomly assigned to an observation group and a control group(50 cases each)using a random number table.The control group received standard hemodialysis treatment and routine oxygen therapy(maintaining oxygen concentration at 28％-30％).The observation group received a dynamic oxygen concentration adjustment protocol:35％-40％oxygen concentration 30 minutes before dialysis,28％-30％concentration maintained for 2-3 hours during dialysis,and adjusted to 32％-35％concentration 30 minutes after dialysis.Both groups underwent 12-week intervention cycles.Primary observation indicators included:oxidative stress markers(superoxide dismutase SOD,malondialdehyde MDA,glutathione peroxidase GSH-Px),anemia-related parameters(hemoglobin Hb,hematocrit HCT,serum erythropoietin EPO),and adverse reaction incidence.Results Baseline data showed no significant differences in oxidative stress markers or anemia parameters between the two groups(P>0.05).After 12 weeks of intervention,the observation group demonstrated significant improvements:SOD levels(128.64±15.32 U/mL vs 105.28±14.67 U/mL)and GSH-Px levels(86.35±10.24 U/mL vs 72.16±9.85 U/mL)were significantly higher than those in the control group,while MDA levels(5.23±1.05 nmol/mL vs 7.86±1.23 nmol/mL)were significantly lower(P<0.05).In terms of anemia improvement,the observation group showed significantly higher Hb levels(112.56±10.34 g/L vs 98.67±9.85 g/L),HCT(33.85±3.21％vs 29.67±3.05％),and EPO levels(186.35±25.67 mIU/mL vs 152.46±23.85 mIU/mL)compared to the control group(P<0.05).Safety assessments revealed that the incidence of adverse reactions in the observation group(6.00％)were significantly lower than in the control group(20.00％)(P<0.05).Correlation analysis indicated that SOD and GSH-Px showed significant positive correlations with Hb,HCT,and EPO,while MDA exhibited significant negative correlations with these anemia indicators(P<0.001).Conclusion The gradient-controlled medical oxygen therapy effectively improved oxidative stress status and enhanced anemia correction in MHD patients,demonstrating a high safety margin and broader clinical adoption.

Abstract:The application of diffuse oxygen enrichment in plateau environments is challenged by CO2 accumulation and uneven oxygen distribution within experimental chambers,compromising both experimental safety and data reliability.This study employed a Computational Fluid Dynamics(CFD)approach to simulate and analyze the airflow organization in a plateau diffuse oxygen enrichment experimental chamber.A physical model of the chamber was constructed,incorporating symmetrical ventilation inlets/outlets and parameters simulating rat respiration.The gas distribution characteristics under different operational conditions were investigated.Simulation results revealed that in the absence of ventilation,CO2 concentrated markedly within the rat's breathing zone.By optimizing the ventilation rate(43.2 m3/h)and air supply velocity(1.7 m/s),in coordination with a 30％oxygen supply,the oxygen concentration in the breathing zone was stabilized at 23.3％with a coefficient of variation of 4.2％,while CO2 levels were maintained under 1000 ppm.The oxygen enrichment efficiency reached 25.56％.This study confirms that optimizing airflow organization is crucial for achieving a safe and controllable oxygen-enriched microenvironment in plateau conditions,providing key parameters and a theoretical basis for the design of related artificial oxygen enrichment experimental equipment.

Abstract:The medical purpose air system is an indispensable component of medical gas systems,with moisture content being a critical indicator that affecting medical air quality.In order to investigate the moisture-handling capabilities of different dryers,two commonly used methods for drying air,namely the refrigerated drying method and the adsorption drying method,were introduced.Through the comparative analysis of the characteristics of typical drying equipment,it had been found that refrigerated dryers offer significant advantages in terms of price,while adsorption dryers deliver higher quality compressed air.It is recommended that adsorption dryers should be given priority consideration in the construction or renovation of medical air systems.

Abstract:Flexible endoscopes are generally dried using compressed air after cleaning and disinfection.To ensure that the clean state after the final rinse is not compromised,the compressed air used must meet the clean quality standards.Moisture,particulate matter and microorganisms are the main contaminants in clean compressed air.At present,medical institutions generally lack the awareness regarding management and control of such risks,primarily due to the absence of explicit control requirements in existing regulatory documents.Based on the principles of risk management,it is imperative to refine the corresponding technical requirements.To effectively ensure that the microbial limits of endoscopes meet standards after cleaning and disinfection,it is recommended to implement the same microbial control measures for compressed air that are as stringent as those for cleaning water.To address the technical gaps in the WS 507-2016 specification,it is advisable to reference the relevant technical requirements for clean compressed air outlined in the Good Manufacturing Practice(GMP)documentation for supplementation and refinement.

Abstract:Objective To explore the effect of transcranial magnetic stimulation device combined with rehabilitation nursing in stroke rehibilitation.Methods A clinical nursing study was conducted on 90 patients(from February 2021 to May 2025).After random grouping,different nursing measures were combined(control group/observation group,45/45 cases)to evaluate the effects of conventional nursing(control group)and transcranial magnetic stimulation combined with rehabilitation nursing(observation group)on the neurological function,limb function,living ability and quality of life of the patients.Result Before nursing,the observation group and the control group compared the upper and lower limbs with National Institutions of Health Stroke Scale(NIHSS)and Fugl-Meyer Assessment Scale(FMA).There was no significant difference in the scores of Basic Activities of Daily Living Scale(BADL)and World Health Organization Quality of Life Scale(WHO-QOL)(P>0.05).The NIHSS score decreased after nursing,and compared with the control group,the observation group decreased more significantly(P<0.05).The scores of FMA(upper and lower limbs)were improved after nursing,and the improvement in the observation group was more significant than that in the control group(P<0.05).BADL score was improved after nursing,and compared with the control group,the observation group improved more significantly(P<0.05),and the WHO-QOL score was improved after nursing,and the observation group improved more significantly(P<0.05).Conclusion The transcranial magnetic stimulation device combined with rehabilitation nursing has demonstrated a marked clinical effect on stroke patients.It has notably improved the neurological and limb functions of the patients,further restored their basic living ability,and resulted in higher overall quality of life scores,which is worthy of broader promotion and clinical adoption.

Abstract:Based on the analysis method of fluidized bed,the structure of adsorption tower of PSAoxygen concentrator was designed,and the structure of three-dimensional axial fluid molecular sieve bed with Skarstrom cycle was selected,the proper height of the adsorption column is studied by controlling the inner diameter of the bed according to the flow rate of the bed in the adsorption column,and according to the influence of the existence of gas in the column,the reserved space and the splitter plate in the adsorption column were analyzed and designed,and the gas storage capacity of the gas storage tank to the adsorption column system was analyzed and designed.In this paper,the proposed adsorption tower design enhances oxygen production efficiency by more than 40％compared to the current stereoscopic axial flow adsorption tower designs.

Abstract:Objective An analysis of the effects of IMRT on radiation precision and hematological parameters in nasopharyngeal carcinoma patients.Methods A total of 87 patients with nasopharyngeal carcinoma admitted from January 2024 to June 2025 were selected and randomly divided into a control group(44 cases)and an observation group(43 cases)by computer-generated random numbers.The control group received the basic IMRT plan without cone-beam CT(CBCT)image guidance,while the observation group received the IMRT plan combined with CBCT image guidance.The target dose coverage,incidence of bone marrow suppression,and changes in quality of life were compared between the two groups.Results The observation group achieved target D95 dose of 68.30±1.20 Gy,showing a 7％improvement in conformity index(0.91±0.03 vs 0.85±0.05,P<0.05).The proportion of irradiated fields with dose deviation>5％decreased by 71％(4.65％vs 15.91％).During treatment,the incidence of grade Ⅲ-Ⅳ bone marrow suppression(11.63％vs 31.82％)and radiation dermatitis(20.93％vs 45.45％)in the observation group was significantly lower than the control group(P<0.05).Additionally,the lowest white blood cell count remained at 3.20±0.40×10^9/L,which was 18.5％higher than the control group(P<0.05).Six months post-treatment,the swallowing function score in the observation group decreased by 23％compared to the control group(24.30±3.20 vs 27.00).Conclusion By enhancing target dose conformity and minimizing normal tissue irradiation,,Intensity-modulated radiotherapy(IMRT)significantly reduced the risks of hematological toxicity and radiation mucosal damage in nasopharyngeal carcinoma patients.The CBCT dynamic positioning technology plays a crucial clinical role in mitigating unplanned dose deviations.

Abstract:Objective To investigate the effects of different airflow patterns and humidification levels on comfort and airway mucosal injury in ICU patients with tracheotomy.Methods A total of 96 ICU tracheotomy patients admitted between January 2022 and January 2025 were selected as subjects.They were randomly divided into an observation group(48 cases)and a control group(48 cases)using a random number table method.The control group received conventional airflow mode(continuous flow)with medium humidification level(60％-70％)for airway management,while the observation group received individually adjusted airflow patterns(e.g.,dual-level flow,adaptive flow)and humidification levels(70％-85％)based on patient conditions.Comparison was made on indicators including comfort scores,incidence of airway mucosal injury,sputum viscosity,and airway resistance.Results The observation group showed superior outcomes compared to the control group in comfort scores,sputum viscosity,and airway resistance(P<0.05).The incidence of airway mucosal injury in the observation group was 8.33％,which is significantly lower than the control group's 27.08％(P<0.05).Conclusion Individualized adjustment of airflow patterns and humidification levels can effectively enhance comfort in ICU patients with tracheotomy,reduce airway mucosal damage,improve airway management outcomes,demonstrating significant clinical value.

Abstract:Objective This study aimed to investigate the clinical therapeutic effects and mechanisms of hyperbaric oxygen(HBO)therapy in patients with pulmonary air embolism(PAE),so as to provide evidence-based guidance and practical reference for the early clinical management of PAE patients.Methods The patient diagnosed through multidisciplinary consultation upon admission was urgently underwent hyperbaric oxygen(HBO)therapy for air embolism.Following the HBO session,comprehensive interventions such as fluid resuscitation support and close monitoring of vital signs were administered.Results After a single session of HBO therapy,the patient's symptoms,including chest tightness,shortness of breath,and dizziness,were completely relieved.The following pulmonary CT angiography revealed complete resolution of air bubbles in the pulmonary arteries,right atrium,and right ventricle.During one-month follow-up period,the patient did not exhibit any sequelae or abnormal manifestations.Conclusion HBO therapy can rapidly reduce and eliminate air bubble obstruction,thereby improving tissue hypoxia.It demonstrated definitive efficacy in the early treatment of PAE,and when combined with multidisciplinary collaboration and comprehensive interventions,significantly enhanced patient's prognosis.

Abstract:Objective This study aimed to explore the influence of a comprehensive nutritional support strategy on the prognosis of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)treated with nasal high-flow oxygen therapy(HFNC).Methods A total of 96 patients with AECOPD admitted to our hospital from May 2023 to April 2025 were selected and randomly divided into the experimental group and the control group using SPSS 23.0 software.Both groups received HFNC treatment,while the control group was given conventional enteral nutrition and the experimental group was provided with a comprehensive nutritional support strategy combining enteral and parenteral nutrition.The levels of serum albumin(ALB),hemoglobin(Hb),transferrin(TF),arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),interleukin-10(IL-10),high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),and the rate of poor clinical prognosis were compared between the two groups.Results After 7 days of treatment,the levels of Hb,ALB,TF,and PaO2 in the experimental group were higher than those in the control group(P<0.05),while the levels of PaCO2,IL-10,hs-CRP,and TNF-α were lower than those in the control group(P<0.05).After 3 months of follow-up,the rate of poor clinical prognosis in the experimental group was lower than that in the control group(P<0.05).Conclusion Compared with conventional enteral nutrition,the comprehensive nutritional support strategy can further improve the nutritional status of AECOPD patients,enhance the therapeutic effect of HFNC,reduce inflammatory response,and improve clinical prognosis.

Abstract:Objective This study aimed to explore the therapeutic potential and clinical utility of electromyographic biofeedback combined with resistance training in the rehabilitation of children with spastic cerebral palsy.Methods Sixty children with spastic cerebral palsy admitted to Xuzhou Medical University Affiliated Hospital from February 2022 to February 2025 were randomly divided into observation and control groups,with 30 patients in each group.The control group received routine rehabilitation training combined with electromyographic biofeedback therapy,while the observation group received resistance training on the basis of the control group's treatment.We compared the improvement of gross motor function,walking endurance and energy expenditure,balance ability and daily living ability between two groups of patients.Results Before treatment,there was no significant difference in Gross Motor Function Measure(GMFM)scores between the two groups of patients in different regions(P>0.05);After treatment,the scores of both groups significantly increased,and the observation group was higher than the control group(P<0.05).Before treatment,there was no significant difference in walking endurance(6 min and 10 min walking tests)and physiological cost index(PCI)between the two groups(P>0.05);After treatment,the observation group showed markedly better walking endurance at 6 and 10 minutes and PCI than the control group(P<0.05).Before treatment,there was no significant difference in the scores of balance capacity and activities of daily living(ADL)between the two groups(P>0.05);After treatment,the scores of both groups improved,and the observation group was notably higher than the control group(P<0.05).Conclusion The application of electromyographic biofeedback combined with resistance training program proved to be highly effective in the treatment of pediatric patients with spastic cerebral palsy,which can significantly enhance gross motor function,walking endurance(with improved energy efficiency),balance capacity and activities of daily living,contributing to superior clinical recovery and warranting broader clinical application.

Abstract:Objective This study aimed to explore the clinical application of high-frequency electricity combined with cryotherapy and oxygen support in the treatment of endobronchial tuberculosis.Methods Patients with bronchial tuberculosis in the hospital were included from January 2021 to November 2025.Eventually,a total of 70 patients were enrolled.The grouping method was the random number table method,and two groups were set up,with 35 cases in each groupThe control group received conventional anti tuberculosis drugs combined with high-frequency electricity and cryotherapy,while the observation group received oxygen support therapy in addition to the control group.The clinical efficacy of both groups was compared.Results The total effective rate of the two treatment groups was compared,and the observation group had asignificant higher rate(P<0.05);Compared with the control group,the observation group had a shorter relief time for symptoms such as sputum,cough,chest tightness,shortness of breath,and hemoptysis(P<0.05);After treatment,all lung function indicators in both groups of patients improved compared to before,with superior improvement in the observation group(P<0.05);The incidence of adverse reactions between groups showed no significant difference(P>0.05).Conclusion In the treatment of endobronchial tuberculosis,the combination of high-frequency electricity and cryotherapy with oxygen support demonstrated both favorable efficacy and high safety.

Abstract:Objective This study aimed to investigate the clinical efficacy of High Flow Nasal Cannula Oxygen Therapy in the treatment of elderly patients with severe pneumonia in emergency settings,and to provide evidence-based support for the selection of emergency oxygen therapy plans.Methods 62 elderly patients with severe pneumonia admitted to our emergency department from January 2023 to June 2024 were selected.They were randomly divided into an observation group(n=31)and a control group(n=31)using a random number table method.The control group received conventional non-invasive mechanical ventilation treatment,while the observation group received nasal high flow oxygen therapy.Both groups received basic treatments including anti-infection,sputum management,and nutritional support.We compared the blood gas analysis indicators,respiratory function indicators,symptom improvement indicators,and clinical outcome indicators between two groups of patients after treatment.Results After treatment,the PaO2 and PaO2/FiO2 in the observation group were significantly higher than those in the control group,while PaCO2 was significantly lower than that in the control group(P<0.05);The respiratory rate of the observation group was significantly lower than that of the control group,and the cough symptom score was significantly lower than that of the control group(P<0.05).Conclusion High-flow nasal oxygen therapy can effectively improve oxygenation,reduce respiratory load,alleviate clinical symptoms,shorten hospital stay,and improve treatment efficacy in elderly patients with severe pneumonia in the emergency settings.

Abstract:Objective This study investigated the preventive effect of the integrated oral-nasal hydrogen supply device on hypoxemia in snoring patients during painless gastroscopy,aiming to provide a reference for clinical practice.Methods A total of 90 snoring patients who underwent painless gastroscopy in our hospital from January 2022 to June 2024 were selected.They were divided into group A,group B and group C using the random number table method,with 30 cases in each group.Group A was given conventional nasal cannula oxygen,group B was given simple mask oxygen therapy,and group C received oxygen via the integrated oral-nasal hydrogen supply device.All patients underwent the examination under the standard anesthesia induction protocol.The changes in pulse oxygen saturation(SpO2),systolic blood pressure(SBP),diastolic blood pressure(DBP)and heart rate(HR)were recorded at T0(before pre-oxygenation),T1(after pre-oxygenation),T2(1 min after the start of examination),T3(3 min after the start of examination),T4(5 min after the start of examination)and T5(after full recovery).In addition,the time consumed for wearing and removing the devices,the duration of hypoxemia,the incidence of hypoxemia and the incidence of adverse events were recorded and compared among the three groups.Results There were no significant difference in SpO2,SBP,DBP and HR among the three groups at T0(P>0.05).At T1-T4,the SpO2 level in group C was notably higher than that in group A and group B(P<0.05),while there was no significant difference in SpO2 level among the three groups at T5(P>0.05).At T2-T4,the SBP,DBP and HR in group C were more stable with smaller fluctuation ranges than those in group A and group B(P<0.05),and no significant difference in SBP,DBP and HR were observed among the three groups at T5(P>0.05).The incidence of hypoxemia and the duration of hypoxemia in group C were lower than those in group A and group B(P<0.05).The time for applying and removing the device in group C was significantly shorter than that in group A and group B(P<0.05),while there was no significant difference in the wearing and removing time between group A and group B(P>0.05).No adverse events such as intraoperative intubation or abortion of the procedure,occurred in any of the three groups.Conclusion All three oxygen inhalation methods hold clinical application value.The integrated oral-nasal hydrogen supply device demonstrated superior comprehensive performance compared to the simple face mask,specifically in reducing the duration of hypoxia,lowering the incidence of hypoxemia,and improving the stability of vital signs in snoring patients undergoing painless gastroscopy,worthy of clinical promotion and application.

Abstract:Objective This study aimed to analyze the effect of focused ultrasound combined with ozone therapy on inflammatory cervical erosion-like changes due to cervical ectropion.Method 200 patients with inflammatory cervical erosion like changes admitted to our hospital from August 2022 to August 2025 were selected for the study.Using random number table method,we divided the patients into a control group and a study group,with 100 cases in each group,and received conventional microwave therapy and focused ultrasound and oxygen therapy,respectively.We compared the treatment effects and inflammatory indicators(IL-6、IL-8、hs-CRP)between two groups,and followed up patients to record their re-pregnancy status,delivery outcomes,and quality of life.Results The total effective rate of the study group was significantly higher than that of the control group(P<0.05).The level of inflammatory response indicators in the study group was remarkably lower than that in the control group after treatment(P<0.05).The re-pregnancy rate of the research group was notably higher the control group,and the incidence of adverse delivery outcomes was markedly lower than the control group(P<0.05).The quality of life score of the research group wassignificantly improved compared to the control group(P<0.05).Conclusion The combination of focused ultrasound and ozone therapy showed promising results for inflammatory cervical ectropion,effectively reducing inflammation,increasing subsequent pregnancy success rates,and promoting favorable delivery outcomes and quality of life,thereby constituting a valuable therapeutic strategy for clinical reference.

Abstract:Objective To explore the effect of a refined carbon dioxide pneumoperitoneum management protocol on the occurrence and severity of postoperative shoulder pain in patients undergoing gynecological laparoscopic surgery.Methods A total of 100 patients who underwent laparoscopic surgery in the Department of Gynecology of the People's Hospital of Hechi from 2022 to 2024 were selected.Using a random number table method,patients were allocated into an observation group and a control group,with 50 patients in each group.The control group received conventional carbon dioxide pneumoperitoneum management during surgery,while the observation group underwent a refined pneumoperitoneum management protocol,including controlled low-pressure pneumoperitoneum,active gas evacuation upon procedure completion,and postural intervention.Outcome measures compared between the two groups included shoulder pain Visual Analogue Scale(VAS)scores at 6,24,and 48 h postoperatively,incidence of postoperative shoulder pain,time to first ambulation,length of hospital stay,rate of additional analgesic administration,and patient satisfaction.Results After intervention,the VAS scores for shoulder pain in the observation group were significantly lower than those in the control group at all time points(P<0.05).The overall incidence of postoperative shoulder pain was 24.00%in the observation group,significantly lower than 56.00%in the control group(P<0.05).Within 24 h after surgery,the rate of additional analgesic administration in the observation group(7 cases,14.00%)was significantly lower than that in the control group(17 cases,34.00%).No statistically significant difference was observed in the incidence of postoperative nausea and vomiting between the two groups.Furthermore,patient satisfaction scores regarding postoperative pain management were significantly higher in the observation group than in the control group(P<0.05).Conclusion Implementing refined carbon dioxide pneumoperitoneum management in patients undergoing gynecological laparoscopic surgery can effectively reduce the severity and incidence of postoperative shoulder pain,promote early patient recovery,and shorten the length of hospital stay,which has significant clinical promotion and application value.

Abstract:Objective To explore the effect of red light irradiation therapeutic apparatus combined with rehabilitation nursing on the psychological resilience,self-efficacy and blood glucose level of patients with diabetic foot.Methods A total of 78 patients with diabetic foot who were admitted to our hospital from May 2023 to December 2024 were included and randomly divided into the control group(routine nursing,39 cases)and the observation group(red light irradiation therapeutic apparatus+rehabilitation nursing,39 cases)by flipping a coin.The changes in psychological resilience,self-efficacy and blood glucose level of the patients in the two groups before and after the intervention were compared and analyzed.Results After the intervention,the psychological resilience scores and self-efficacy of both groups of patients showed an upward trend,but the observation group showed a greater improvement(P<0.05).After the intervention,the levels of various dimensions of blood glucose(glycated hemoglobin,fasting blood glucose,and 2-hour postprandial blood glucose)in both groups of patients were lower than those before the intervention,and the comparison between the two groups showed that the observation group was better(P<0.05).Conclusion Red light irradiation therapeutic apparatus combined with rehabilitation nursing can effectively improve the psychological resilience and self-efficacy of patients with diabetic foot and control blood glucose level.

Abstract:Objective To compare and study the clinical efficacy of CO2 laser combined with conventional drugs in the treatment of inflammatory skin diseases.Methods A total of 70 patients with inflammatory skin diseases from the Department of Dermatology in our hospital from October 2023 to March 2025 were selected and divided into Group A and Group B according to different treatment regimens.Group A was treated with conventional drugs,while Group B was treated with CO2 laser combined with conventional drugs,with 35 cases in each group.The skin indicators(TEWL and WCSC),inflammatory indicators(IL-2,IL-4,and IFN-γ),quality of life(DLQI score),clinical efficacy and adverse reactions(skin redness and swelling,pain,and pigmentation)of the two groups were compared.Results After treatment,the TEWL levels in both groups decreased,and the WCSC levels increased.Moreover,the improvement degree in Group B was better than that in Group A(P<0.05).After treatment,the levels of IL-2,IL-4 and IFN-γ in both groups decreased,and the improvement degree in Group B was better than that in Group A(P<0.05).After treatment,the DLQI scores of both groups decreased,and the improvement degree of Group B was better than that of Group A(P<0.05).The total effective rate of Group B(94.29%)was higher than that of Group A(77.14%)(P<0.05).The incidence of adverse reactions in the two groups was similar(P>0.05).Conclusion The clinical efficacy of CO2 laser combined with conventional drugs in the treatment of inflammatory skin diseases is remarkable.It can improve skin indicators and inflammatory indicators,enhance the quality of life,and does not increase adverse reactions.

Abstract:Objective To explore the effect of multi-dimensional nursing intervention on patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with respiratory failure treated with high-flow nasal cannula oxygen therapy(HFNC)under the goal-oriented strategy.Methods A total of 92 patients with AECOPD complicated with respiratory failure in our hospital from June 2024 to May 2025 were selected and randomly divided into a reference group(n=46,receiving routine care)and an experimental group(n=46,receiving multi-dimensional care under the goal-oriented strategy on the basis of routine care)by the random number table method.The blood gas indicators,psychological states and comfort levels of the two groups before and after nursing were compared,and the rehabilitation process and complications were statistically analyzed.Results After the nursing care,the blood oxygen saturation(SaO2),arterial hydrogen ion concentration index(pH),and arterial partial pressure of oxygen(PaO2)in the experimental group were higher than those in the reference group,while the arterial partial pressure of carbon dioxide(PaCO2)was lower than that in the reference group(P<0.05).After the nursing care,the negative affect(NA)score of the experimental group was lower than that of the reference group,while the positive affect(PA)score and the Kolcaba's General Comfort Questionnaire(GCQ)score of the experimental group were higher than those of the reference group(P<0.05).The oxygen therapy time,the length of stay in the intensive care unit(ICU),and the length of hospital stay in the experimental group were shorter than those in the reference group,and the incidence of complications was lower than that in the reference group(P<0.05).Conclusion When implementing HFNC in patients with AECOPD complicated with respiratory failure,multi-dimensional nursing under the goal-oriented strategy can not only improve the blood gas status of patients,accelerate their recovery,but also reduce the occurrence of complications,relieve their negative emotions,and enhance the comfort of patients.

Abstract:Quality control supervision and management of medical equipment includes its importance,system composition,specific practical links,challenges and countermeasures.Through literature review and case analysis,medical equipment quality control has been deeply studied throughout the whole life cycle of the equipment,including its procurement,acceptance,use,and maintenance and scrapping.At the same time,the application of information technology in quality control,such as Internet of Things,big data analysis and artificial intelligence,is also discussed.At present,medical equipment quality control faces challenges such as disunified standards and imperfect supervision system.Aiming at these problems,this paper proposes strategies to improve quality control standards,strengthen supervision system construction and optimize quality control process.The results aim to provide comprehensive and systematic references for the supervision and management of medical equipment quality control.