Abstract:Objective To explore the risk factors for convulsions in children with viral encephalitis and meningi-tis,and propose targeted nursing strategies accordingly.Methods A retrospective case-control study was conducted,involving 112 children with viral encephalitis and meningitis admitted to Putian Children's Hospital from January 2023 to June 2025.They were divided into an observation group(40 cases with convulsions)and a control group(72 cases without convulsions)based on the occurrence of convulsions.Clinical data from both groups were collected and compared.Uni-variate analysis was performed on potential risk factors,and variables with statistical significance were included in a mul-tivariate Logistic regression analysis to identify independent risk factors for convulsions.Results Univariate analysis revealed that the proportions of children with fever duration≥3 days,maximum body temperature≥39℃,disturbance of consciousness,positive meningeal irritation signs,positive pyramidal tract signs,and abnormal electroencephalogram(EEG)were significantly higher in the observation group than in the control group(all P<0.001).Multivariate Logistic regression analysis further confirmed that fever duration≥3 days(OR=4.256,95%CI:2.134～8.489),maximum body temperature≥39℃(OR=3.568,95%CI:1.823～6.983),disturbance of consciousness(OR=5.127,95%CI:2.568～10.236),positive pyramidal tract signs(OR=4.875,95%CI:2.432～9.772),and abnormal EEG(OR=5.678,95%CI:2.845～11.332)were independent risk factors for convulsions in children.Conclusion Prolonged fever duration,high fever,disturbance of consciousness,positive py-ramidal tract signs,and abnormal EEG significantly increase the risk of convulsions in children with viral encephalitis and meningitis.In clinical practice,enhanced early iden-tification,intensive monitoring,and anticipatory nursing care targeting these high-risk factors should be implemented to prevent convulsions and improve prognosis.

Abstract:Objective To explore the impact of whole-course tracking nursing based on key node control on the qual-ity of rescue in cardiac arrest patients undergoing cardiopulmonary resuscitation(CPR).Methods A retrospective study was conducted on 132 cardiac arrest patients who underwent CPR admitted to Tai'an Eighty-eight Hospital from January 2023 to January 2025.According to the nursing model applied,the patients were divided into an observation group(receiving whole-course tracking nursing based on key node control,n=66)and a control group(receiving routine nursing,n=66).The rates of return of spontaneous circulation(ROSC),CPR duration,post-CPR physiological parameters,and neurological func-tion recovery were compared between the two groups.Results Compared with the control group,the observation group showed a significantly higher rate of ROSC(P=0.037)and a significantly shorter CPR duration(P<0.001).After CPR,systolic blood pressure,diastolic blood pressure,heart rate,respiratory rate,and blood oxygen saturation in the observation group were superior to those in the control group(P<0.001).Before resuscitation,there was no significant difference in the Glasgow Coma Scale(GCS)scores between the two groups(P=0.142).After resuscitation,the GCS scores of both groups showed an increas-ing trend over time.Compared with the control group,the observation group had significantly higher GCS scores at 24h,48h,and 72h post-resuscitation(P<0.001).Conclusion In the rescue of cardiac arrest patients undergoing CPR,whole-course tracking nursing based on key node control can improve the rate of ROSC,shorten CPR duration,promote the stabilization of physiological parameters after CPR,and facilitate the recovery of patients'neurological function.

Abstract:Objective To investigate the effects of cetirizine combined with budesonide inhalation therapy on pulmonary function in children during acute asthma exacerbations.Methods A total of 80 children with acute asthma exacerbations admitted to Sanming Second Hospital from December 2022 to June 2025 were selected as study subjects.They were randomly divided into an observation group(cetirizine combined with budesonide,40 cases)and a control group(budesonide alone,40 cases).The symptom recovery time,levels of inflammatory factors[interleukin-6(IL-6),C-reac-tive protein(CRP)],pulmonary function indicators[forced expiratory volume in one second(FEV1),forced vital capacity(FVC),and peak expiratory flow rate(PEFR)],and the incidence of adverse reactions were compared between the two groups.Results The recovery times for symptoms such as cough,wheezing,and dyspnea in the observation group were significantly shorter than those in the control group(all P<0.001).After treatment,serum IL-6 and CRP levels in the obser-vation group were significantly lower than those in the control group(both P<0.001).FEV1,FVC,and PEFR in the obser-vation group were significantly higher than those in the control group(all P<0.001).There was no statistically significant difference in the incidence of adverse reactions between the two groups(12.50%vs.7.50%,P=0.456).Conclusion Cet-irizine combined with budesonide inhalation therapy for children during acute asthma exacerbations can significantly short-en the time to clinical symptom relief,effectively reduce inflammatory factor levels,improve pulmonary function,and does not increase the risk of adverse reactions.

Abstract:Objective To explore the clinical efficacy of vacuum sealing drainage(VSD)in the treatment of bone infection following open tibial fracture surgery,and to analyze its impact on the infection control process,inflammatory response,and joint function.Methods A total of 62 patients with bone infection after open tibial fracture surgery ad-mitted to Xiamen Third Hospital from February 2020 to January 2025 were selected and divided into two groups according to the random number table method,with 31 cases in each group.The control group received conventional wound man-agement(debridement,dressing change,antibiotics),while the observation group was additionally treated with VSD.The infection control time,frequency of dressing changes during treatment,levels of inflammatory markers[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)]before and after treatment,and knee joint function(HSS score)at 3 months postoperatively were compared between the two groups.Results The infection control time in the observation group was significantly shorter than that in the control group(P<0.001),and the frequency of dressing changes was significantly reduced(P<0.001).After 4 weeks of treatment,the levels of IL-6,TNF-α,and CRP in both groups were significantly lower than those before treatment(P<0.05),and the levels of these markers in the observation group were sig-nificantly lower than those in the control group(P<0.001).At 3 months postoperatively,the HSS score in the observation group was significantly higher than that in the control group(P<0.05).Conclusion In the treatment of bone infection following open tibial fracture surgery,the combined application of vacuum sealing drainage technology can effectively ac-celerate infection control,reduce the frequency of dressing changes,alleviate systemic inflammatory response,and promote the recovery of knee joint function.

Abstract:Objective To explore the application effect of optimized prehospital emergency nursing based on a structured process in acute stroke patients.Methods A total of 100 acute stroke patients admitted to our hospital from January to December 2024 were selected and divided into two groups using a computer-generated random number table.The control group(50 cases)received conventional prehospital emergency care,while the observation group(50 cases)received optimized emergency nursing centered on rapid response,multidisciplinary team standardized assessment and intervention.The emergency-related time indicators(dispatch,onscene arrival,emergency initiation,completion of man-agement,and transport time),vital signs(blood pressure,heart rate,respiratory rate,oxygen saturation)before and after intervention,neurological deficit(assessed using the National Institutes of Health Stroke Scale,NIHSS),incidence of complications,and satisfaction with nursing services were compared between the two groups.Results Compared with the control group,all emergency time indicators in the observation group were significantly shortened(all P<0.001).After intervention,systolic blood pressure,diastolic blood pressure,heart rate and respiratory rate were significantly reduced,and oxygen saturation was significantly increased in the observation group,with the degree of improvement superior to that of the control group(all P<0.001).NIHSS scores at admission,24h,72h and 7d after admission were significantly lower in the observation group than in the control group(all P<0.05),indicating better neurological recovery.In addition,the overall complication rate in the observation group was low-er than that in the control group(4.00%vs.16.00%,P=0.046),and satisfaction with nursing services was higher(94.00%vs.70.00%,P=0.002).Conclusion In prehospital emergency management of acute stroke patients,implementation of structured optimized emergency nursing interventions can effectively improve emergency efficiency,stabilize vital signs more effectively,promote neurological recovery,reduce the risk of complications,and increase patient satisfaction.

Abstract:Objective To investigate the efficacy and safety of adenosine triphosphate(ATP)in the emergency treatment of paroxysmal supraventricular tachycardia(PSVT),and to analyze the impact of age,heart rate,and anxiety state on the outcome of ATP cardioversion,aiming to provide references for individualized emergency management.Meth-ods A retrospective analysis was conducted on 144 PSVT patients admitted to the emergency department of our hospital from February 2023 to December 2024,all of whom received intravenous ATP treatment.Patients were divided into an effective group(124 cases)and an ineffective group(20 cases)based on cardioversion outcome.Baseline characteristics were compared between the two groups,and multivariate logistic regression analysis was used to identify independent risk factors for failed ATP cardioversion.Results The overall successful cardioversion rate with ATP was 86.11%(124/144).The incidence of adverse reactions was 20.83%(30/144),all of which were transient.Univariate analysis showed that the heart rate and Generalized Anxiety Disorder-2(GAD-2)scores were significantly higher in the ineffective group compared to the effective group(all P<0.05).Stratified analysis indicated that the successful cardioversion rate was significantly low-er in patients aged≥70 years,with a heart rate≥180 beats/min,and with a GAD-2 score≥3(all P<0.05).Multivariate regression analysis identified age≥70 years(OR=5.220,95%CI:1.042～26.149),heart rate≥180 beats/min(OR=6.018,95%CI:1.702～21.285),and GAD-2 score≥3(OR=3.972,95%CI:1.338～11.788)as independent risk factors for failed ATP cardioversion.Conclusion ATP is a safe and effective drug for terminating PSVT in the emergency setting.Ad-vanced age,extremely fast heart rate,and concomitant anxiety state may be high-risk factors predicting ATP cardioversion failure.In emergency management,enhanced monitor-ing and consideration of alternative treatment options are warranted for such high-risk patients to optimize management strategies.

Abstract:Objective This study aimed to compare the efficacy of different doses of budesonide combined with sal-butamol via nebulization in the treatment of acute exacerbations of bronchial asthma.Methods Sixty patients with mild to moderate acute exacerbations of bronchial asthma admitted to our hospital from March 2023 to March 2025 were selected and randomly divided into two groups,with 30 patients in each group.The control group received 0.5 mg budesonide+5 mg salbutamol via nebulization,while the observation group received 1 mg budesonide+5 mg salbutamol via nebulization,twice daily for 7 days.The time to symptom relief,the rate of complete symptom control at day 7,pulmonary function in-dices[forced expiratory volume in 1 second(FEV₁),FEV₁/forced vital capacity(FVC),peak expiratory flow(PEF)],and in-flammatory markers[interleukin-4(IL-4),IL-5,IL-13,fractional exhaled nitric oxide(FeNO)]were compared between the two groups.Results The time to disappearance of wheezing(P<0.001)and the time to reduction of cough to mild level(P<0.001)were shorter in the observation group than in the control group.The rate of complete symptom control at day 7 was higher in the observation group than in the control group(86.67%vs.63.33%,P=0.037).After treatment,improvements in FEV₁(P=0.018),FEV₁/FVC(P=0.012),and PEF(P=0.046)were greater in the observation group than in the control group.The levels of IL-4,IL-5,IL-13,and FeNO after treatment were also significantly lower in the observation group than in the control group(P<0.001).Conclusion For mild to moderate acute exacerbations of bronchial asthma,nebulization with 1 mg budesonide combined with salbutamol is superior to the 0.5 mg dose regimen in promoting symptom relief,improving pulmonary function,and reducing airway inflammation,demonstrating better clinical efficacy.

Abstract:Objective To investigate the impact of surgical timing on the prognosis of patients with traumatic in-tracranial hemorrhage.Methods A total of 104 patients with traumatic intracranial hemorrhage admitted to the Depart-ment of Neurosurgery at Zhangzhou Third Hospital from September 2019 to December 2024 were enrolled and randomized by a random number table into a control group and an early-surgery group(n=52 each).The control group received initial conservative management,while the early-surgery group underwent early surgical intervention.Functional outcomes,levels of consciousness and neurological deficit scores,complication rates,and mortality were compared between groups.Re-sults The number of patients achieving outcome grades IV-V was higher in the early-surgery group than in the control group(P<0.05).There were no between-group differences in Glasgow Coma Scale(GCS)and National Institutes of Health Stroke Scale(NIHSS)scores before intervention(P>0.05).Post-intervention,GCS was higher and NIHSS was lower in the early-surgery group compared with the control group(both P<0.05).The incidence of complications and the mortality rate were both lower in the early-surgery group than in the control group(both P<0.05).Conclusion Among patients with traumatic intracranial hemorrhage,earlier surgical intervention is associated with more favorable clinical outcomes,greater improvement in neurological function,and reduced risks of complications and death.

Abstract:Objective To investigate the effects of pathway-based comprehensive thermal insulation nursing model combined with team collaborative nursing on coagulation function and other indicators in emergency trauma pa-tients.Methods A total of 126 emergency trauma patients admitted to the emergency department of our hospital from January 2023 to December 2024 were selected and divided into a control group and an observation group using a random number table,with 63 cases in each group.The control group received routine nursing care,while the observation group received pathway-based comprehensive thermal insulation nursing combined with team collaborative nursing in addition to the routine care.Both groups received nursing interventions for 1 week.Coagulation function[thrombin time(TT),pro-thrombin time(PT),activated partial thromboplastin time(APTT)],body temperature,and disease status[Acute Physiology and Chronic Health Evaluation II(APACHE II)]were compared between the two groups before nursing and 1 hour after nursing.Emergency rescue-related indicators(emergency rescue time,total hospital stay)were also compared between the two groups,and the incidence of adverse events during nursing was compared.Results At 6 hours and 24 hours after nursing intervention,TT and PT in the observation group were shorter than those in the control group,body temperature was higher than that in the control group,and APACHE II scores were lower than those in the control group(P<0.001).Emergency rescue time and total hospital stay in the observation group were shorter than those in the control group(P<0.001).The total incidence of adverse events in the observation group was lower than that in the con-trol group(4.76%vs.15.87%,P<0.05).Conclu-sion The implementation of pathway-based comprehensive thermal insulation nursing model combined with team collab-orative nursing for emergency trauma patients can improve their coagulation function and body temperature levels,enhance disease status,improve rescue outcomes,and effectively prevent the risk of adverse events.

Abstract:Objective To explore the application value of salbutamol combined with montelukast sodium in chil-dren with bronchopneumonia complicated by acute asthma attack.Methods A retrospective analysis was conducted on the clinical data of 150 children with bronchopneumonia complicated by acute asthma attack admitted to Rugao Bo'ai Hospital from January 2023 to December 2024.According to the treatment regimen,they were divided into an observation group(salbutamol combined with montelukast sodium,n=75)and a control group(salbutamol alone,n=75).The time to clinical symptom improvement,pulmonary function,inflammation and immune indicators,and adverse reactions were com-pared between the two groups.Results The time to fever resolution,cough resolution,wheezing resolution,and pulmo-nary rale resolution in the observation group were significantly shorter than those in the control group(P<0.001).Before treatment,there were no significant differences in the levels of FEV1,FVC,FEV1/FVC,IL-6,TNF-α,and IgE between the two groups(P>0.05).After treatment,pulmonary function,inflammation and immune indicators were significantly im-proved in both groups.The levels of FEV1,FVC,and FEV1/FVC in the observation group were significantly higher than those in the control group,while the levels of IL-6,TNF-α,and IgE were significantly lower than those in the control group(P<0.001).There was no significant difference in the incidence of adverse reactions between the two groups(6.67%vs.13.33%,P>0.05).Conclu-sion For children with bronchopneumonia compli-cated by acute asthma attack,the treatment regimen of salbutamol combined with montelukast sodium can rapidly alleviate the patient's condition,reduce inflammatory response,improve lung function,and exhibits a favorable safety profile.

Abstract:Objective To analyze the application effect of the PDSA theory-based optimized management model in the emergency treatment of patients with hemorrhagic stroke.Methods Sixty patients with hemorrhagic stroke treated in our hospital from August 2023 to August 2024 were selected and randomly divided into an observation group(30 cases)and a control group(30 cases)using a random number table.The control group received the hospital's conventional man-agement model,while the observation group received the PDSA optimized management model.The rescue effects(preop-erative preparation time,CT completion time,emergency response time)were compared between the two groups.Changes in self-care ability[Barthel Index(BI)]and neurological function[National Institutes of Health Stroke Scale(NIHSS)]were compared between the two groups before intervention and after 2 months of intervention.Meanwhile,changes in manage-ment satisfaction were recorded for both groups.Results The preoperative preparation time,CT completion time,emer-gency response time,and intravenous thrombolysis time in the observation group were all shorter than those in the control group(P<0.05).After management,the BI score and satisfaction rate in the observation group were higher than those in the control group,while the NIHSS score was lower than that in the control group(P<0.05).Conclusion The PDSA theo-ry-based optimized management model can effectively shorten the emergency response time for patients with hemorrhagic stroke and improve the quality of clinical care.

Abstract:Objective To analyze the clinical features,diagnosis,and treatment of acute promyelocytic leukemia(APL)complicated by disseminated intravascular coagulation(DIC),and to provide a reference for the diagnosis and treat-ment of similar clinical cases.Methods A retrospective analysis was conducted on a 34-year-old female patient admit-ted to the Department of Hematology,Quanzhou First Hospital,Fujian Province,in 2024.The patient was diagnosed with APL complicated by DIC and stratified as intermediate-risk based on complete blood count,coagulation function,bone marrow morphology,and flow cytometry.Treatment included blood products to correct DIC.Upon high suspicion of APL,all-trans retinoic acid induction therapy was initiated immediately.After confirmation of the diagnosis,arsenious acid was added to form a dual induction regimen.Piperacillin-tazobactam was administered for infection control,alongside simul-taneous DIC management and supportive care.Regular monitoring of complete blood count,coagulation function,bone marrow morphology,and the PML-RARα gene was performed.Results The patient's coagulation function returned to normal 10 days after admission,and complete remission was achieved within one month.During the one-year follow-up period,the patient's PML-RARα fusion gene remained continuously negative,complete blood count and coagulation function were normal,with no signs of disease recurrence.Conclusion Pancytopenia and coagulation abnormalities are important indicators for diagnosing APL complicated by DIC.Prompt treatment with all-trans retinoic acid combined with arsenious acid,along with active correction of coagulation function,infection control,and implementation of supportive care,can contribute to achieving sustained remission.

Abstract:Objective To investigate the clinical efficacy of the Wenyang Lishui method combined with non-in-vasive ventilation in patients with acute exacerbation of chronic heart failure(AECHF).Methods A total of 125 AE-CHF patients admitted to Wuping County Hospital from January 2021 to December 2024 were selected and divided into an observation group(63 cases)and a control group(62 cases)according to the random number table method.The control group received conventional Western medical treatment,while the observation group received additional treatment with the Wenyang Lishui method and non-invasive ventilation.Blood gas parameters[pH,oxygen saturation(SaO₂),partial pressure of oxygen(PaO₂),partial pressure of carbon dioxide(PaCO₂)],cardiac function indicators[left ventricular ejection fraction(LVEF),cardiac output(CO)],inflammatory markers[C-reactive protein(CRP),interleukin-6(IL-6)],traditional Chinese medicine(TCM)syndrome scores,and primary efficacy indicators(improvement rate of NYHA functional class,The achievement rate of NT-proBNP/BNP)were compared between the two groups before and after treatment.Adverse reactions were recorded.Results Before treatment,there were no statistically significant differences in any indicators between the two groups(P>0.05).After treatment,pH,SaO₂,PaO₂,LVEF,and CO in the observation group were significantly higher than those in the control group,while PaCO₂,CRP,IL-6,and TCM syndrome scores were significantly lower(P<0.001).The improvement rate of NYHA functional class(87.30%vs.67.74%)and NT-proBNP/BNP(92.06%vs.77.42%)were significantly higher in the observation group than in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(11.29%vs.6.35%,P>0.05).Conclusion Based on conventional Western medical treatment,the combination of the Wenyang Lishui meth-od and non-invasive ventilation can more effectively improve blood gas status,cardiac function,reduce inflammatory re-sponse and clinical symptoms,and enhance overall efficacy in AECHF patients,with a favorable safety profile.

Abstract:Objective To investigate the risk factors for ventricular arrhythmias(VA)in elderly patients with acute myocardial infarction(AMI)after emergency percutaneous coronary intervention(PCI),and to develop a risk pre-diction model.Methods A retrospective analysis was conducted on 150 elderly patients(≥60 years)with AMI who underwent emergency PCI at Longyan First Hospital from January 2022 to December 2024.Based on the occurrence of VA within 7 days after surgery,patients were divided into the VA group(n=38)and the non-VA group(n=112).Baseline data,electrocardiographic parameters(fragmented QRS duration,frontal QRS-T angle),and inflammatory markers[neu-trophil-to-lymphocyte ratio(NLR)]were collected and compared between the two groups.Univariate and multivariate logistic regression analyses were used to identify independent risk factors for VA,and a prediction model was constructed accordingly.The predictive performance of the model was evaluated using the receiver operating characteristic(ROC)curve.Results Among the 150 patients,the incidence of postoperative VA was 25.33%(38/150).Multivariate logistic regression analysis showed that preoperative Killip class Ⅲ～Ⅳ(OR=3.495,95%CI:1.155～10.574),prolonged fragmented QRS duration(OR=1.066,95%CI:1.008～1.127),increased frontal QRS-T angle(OR=1.123,95%CI:1.069～1.179),and elevated NLR(OR=1.544,95%CI:1.209～1.973)were independent risk factors for VA in elderly AMI patients after emer-gency PCI(P<0.05).The prediction model based on these factors was:Logit(P)=-19.909+1.251×preop-erative Killip class+0.064×fragmented QRS duration+0.116×frontal QRS-T angle+0.435×NLR.The area under the ROC curve for this model in predicting VA was 0.920(95%CI:0.861-0.978).Conclusion Cardiac dysfunction(high Killip class),abnormal myocardial electrical conduction(prolonged fragmented QRS duration,increased QRS-T angle),and systemic inflammatory response(elevated NLR)are important risk factors for VA in elderly AMI patients after emer-gency PCI.The prediction model integrating these indicators demonstrates good discriminative ability,which may assist in early clinical identification of high-risk patients.

Abstract:Pulmonary rehabilitation(PR)training for patients with acute respiratory distress syndrome(ARDS)is still in the clinical exploration stage.ARDS has a complex pathogenesis,a high incidence rate,rapid onset,and a poor prognosis.The more severe the ARDS,the longer the patient's use of a ventilator and the higher the mortality rate.Pulmo-nary rehabilitation is an important part of the treatment for ARDS patients.Currently,the PR training for ARDS patients is still in the clinical exploration stage,and no relevant literature has been found on standardized nursing plans for severe ARDS patients.Through literature review,this research organization has confirmed the effectiveness of standardized PR nursing plans in improving the respiratory function and quality of life of severe ARDS patients.This article aims to system-atically sort out the key intervention measures in this field,with the expectation of having significant theoretical and practi-cal value for the standardized care of severe ARDS patients.

Abstract:Objective To explore the clinical application value of Ultrasound Biomicroscopy(UBM)examination in patients with Acute Angle-Closure Glaucoma(AACG)complicated by ciliary body detachment after an attack.Meth-ods One hundred patients diagnosed with AACG after an attack at the Department of Ophthalmology,Beijing Fangshan District First Hospital from January 2019 to December 2023 were selected as the observation group.Concurrently,100 healthy individuals undergoing physical examinations were randomly selected as the control group.The anatomical struc-ture parameters of the eyes were compared between the two groups.The state of ciliary body detachment and the angle opening status were analyzed in the observation group.Results The lens thickness in the observation group was signif-icantly greater than that in the control group(P<0.001).The anterior chamber depth,axial length,angle-opening distance at 500 μm(AOD500),and trabecular-ciliary process distance in the observation group were all lower than those in the control group(P<0.001).There was also a difference in iris configuration between the two groups.The observation group predominantly presented with a convex iris configuration(94.00%),while the control group mainly exhibited a flat iris con-figuration(97.00%).Regarding ciliary body detachment status,partial ciliary body detachment was the main type(62.00%),and 360-degree ciliary body detachment accounted for 38.00%.Conclusion UBM examination can accurately reveal the ocular anatomical structural characteristics and the status of ciliary body detachment in patients with AACG complicat-ed by ciliary body detachment,providing unique clinical value for the research,diagnosis,and treatment of angle-closure glaucoma.

Abstract:Objective To investigate the intervention effect of a diversified nursing model on elderly patients with chronic heart failure(CHF)and malnutrition.Methods A total of 200 elderly patients with CHF and malnutrition ad-mitted to The Affiliated People's Hospital of Jiangsu University from July 2024 to July 2025 were selected as the study sub-jects.They were randomly divided into an observation group(receiving the diversified nursing model,n=100)and a control group(receiving routine nursing care,n=100)using a random number table.Nutrition-related indicators[serum albumin(ALB),hemoglobin(Hb),prealbumin(PA)],cardiac function-related indicators[left ventricular ejection fraction(LVEF),brain natriuretic peptide(BNP)],negative emotions(SAS score and SDS score),quality of life(MLHFQ score),and the time required for improvement in cardiac function and nutritional status were compared.Results Before the interven-tion,there were no significant differences between the two groups in ALB,Hb,PA,LVEF,BNP,SAS score,SDS score,and MLHFQ score(P>0.05).After the intervention,all the above indicators improved significantly compared to pre-interven-tion levels in both groups.Furthermore,the ALB,Hb,PA,and LVEF in the observation group were significantly higher than those in the control group(P<0.001),while the SAS score,SDS score,BNP,and MLHFQ score were significantly lower than those in the control group(P<0.001).The time required for a 2-grade improvement in cardiac function(P<0.001)and the time for nutritional status to return to normal(P<0.001)were significantly shorter in the observation group than in the control group.Conclusion In the treatment of elderly patients with CHF and malnutrition,the diversified nursing model is beneficial in correcting mal-nutrition,improving cardiac function,alleviating negative emotions,enhancing quality of life,and shortening the time re-quired for improvement in both cardiac function and nutritional status.

Abstract:Objective To investigate the clinical effect of standardized pre-hospital emergency intervention on patients with premature rupture of membranes(PROM)complicated by preterm labor.Methods A retrospective collec-tion was conducted on 100 patients with PROM complicated by preterm labor admitted to our hospital from January 2020 to May 2025.Based on the actual pre-hospital intervention model received,they were divided into two groups:the control group(n=50)received routine pre-hospital emergency intervention,while the observation group(n=50)received standard-ized pre-hospital emergency intervention.The two groups were compared regarding uterine contraction inhibition time,treatment duration,tocolysis success rate,incidence of adverse events,neonatal Apgar score,maternal psychological status,total clinical effective rate,and emergency care satisfaction.Results The uterine contraction inhibition time(P<0.001)and treatment duration(P<0.001)in the observation group were significantly shorter than those in the control group.The tocolysis success rate was higher in the observation group than in the control group(86.00%vs.66.00%,P=0.019),while the total incidence of adverse events was lower(6.00%vs.24.00%,P=0.012).The total Apgar score at 5 minutes after birth was significantly higher in the observation group than in the control group(P<0.001).After intervention,the maternal anxiety and depression scores were significantly lower in the observation group than in the control group(P<0.001).The total clinical effective rate(94.00%vs.74.00%,P=0.006)and total emergency care satisfaction rate(98.00%vs.80.00%,P=0.004)were significantly better in the observation group than in the control group.Conclusion Compared with rou-tine intervention,standardized pre-hospital emergency intervention can more effectively shorten the uterine contraction inhibition time and treatment duration,improve the tocolysis success rate,enhance neonatal outcomes and maternal psy-chological status,and increase clinical efficacy and patient satisfaction in patients with PROM complicat-ed by preterm labor.

Abstract:Objective To investigate the independent risk factors for peripheral intravenous infusion extravasation in hospitalized pediatric patients and propose corresponding intervention strategies.Methods A retrospective analysis was conducted on the clinical data of 1557 pediatric patients who received peripheral intravenous infusion at our hospital from January 2024 to December 2024.Among them,55 children who experienced infusion extravasation were designated as the Extravasation Group.Using simple random sampling at a 1:4 ratio,220 children were selected from the 1502 children without extravasation during the same period to form the Control Group.General data of both groups were collected and compared.Multivariate logistic regression analysis was used to identify the independent risk factors for infusion extravasation.Results Univariate analysis showed statistically significant differences between the two groups in terms of age,puncture site,drug os-motic concentration,and working years of the puncture nurse(P<0.05).Multivariate logistic regression analysis revealed that age 0～3 years(OR=2.273,95%CI:1.154～4.478),puncture site on the dorsum of the foot(OR=2.143,95%CI:1.092～4.205),infusion of hypertonic solution(OR=3.511,95%CI:1.190～10.360),and puncture nurse's work experience<1 year(OR=2.418,95%CI:1.314～4.448)were independent risk factors for peripheral intravenous infusion extravasation in hospitalized pediatric patients(P<0.05).Conclusion Peripheral intravenous infusion extravasation in hospitalized pediatric patients is closely as-sociated with young age(0-3 years),dorsum of the foot puncture,infusion of hypertonic solutions,and low seniority of the puncture nurse(<1 year).Clinical practice should focus on these high-risk factors and develop targeted nursing intervention measures to reduce the incidence of infusion extravasation and ensure the safety of pediatric treatment.

Abstract:Objective To explore the efficacy of systematic enhanced emergency treatment in patients with trau-matic hemopneumothorax complicated by shock.Methods A total of 60 patients with traumatic hemopneumothorax complicated by shock admitted to the Department of Thoracic Surgery,Affiliated Hospital of Nantong University from March 2022 to March 2025 were selected as the study subjects.According to the random number table method,they were divided into an observation group(receiving systematic enhanced emergency treatment on the basis of conventional emer-gency care,30 cases)and a control group(receiving only conventional emergency treatment,30 cases).Vital signs,blood gas indicators,shock-related parameters,complication rates,and prognosis were compared between the two groups.Re-sults Before treatment,there were no significant differences between the two groups in heart rate,systolic blood pressure,diastolic blood pressure,respiratory rate,arterial partial pressure of oxygen(PaO₂),partial pressure of carbon dioxide(PaCO₂),oxygen saturation(SpO₂),pH value,shock index,or urine output(P>0.05).At 24 hours after treatment,all the above vital signs,blood gas indicators,and shock-related parameters were significantly improved in both groups,and the improvement was more pronounced in the observation group compared to the control group(P<0.001).Compared with the control group,the observation group had a lower complication rate(13.33%vs.36.67%,P=0.037),shorter hospital stay(P<0.001),and lower mortality rate(3.33%vs.20.00%,P=0.044).Conclusion Systematic enhanced emergency treatment can effectively improve vital signs,blood gas indicators,and shock-related parameters in patients with traumatic hemopneumothorax complicated by shock,reduce the complication rate and mortality,and shorten hospital stay.