Abstract:Objective To explore the application of high-resolution magnetic resonance imaging(HR-MRI)and multi-slice spiral CT(MSCT)in preoperative staging diagnosis of rectal cancer.Methods 157 patients with rectal cancer treated were se-lected as the research subjects.All patients underwent preoperative HR-MRI and MSCT examinations,and the final standard was the surgical pathological diagnosis.Kappa test was used to evaluate the value of HR-MRI and MSCT in the staging diagnosis of rectal cancer.Results A total of 157 patients with pathologically confirmed rectal cancer were identified,including 25 in stage T1,44 in stage T2,50 in stage T3,and 38 in stage T4,while,37 cases in stage N0,74 cases in stage N1,and 46 cases in stage N2.Kappa test was used,HR-MRI diagnosis of rectal cancer T staging showed complete consistency with pathological diag-nosis results(Kappa=0.879,P<0.05),and MSCT diagnosis of rectal cancer T staging showed high consistency with pathological diagnosis results(Kappa=0.784,P<0.05),HR-MRI and MSCT diagnosis of rectal cancer N staging showed high consistency with pathological diagnosis results(Kappa=0.799,0.785,P<0.05),and HR-MRI combined with MSCT diagnosis of rectal can-cer N staging showed complete consistency with pathological diagnosis results(Kappa=0.910,P<0.05).The combined diagnosis of rectal cancer lymph node metastasis improved accuracy and sensitivity,with statistically significant differences(P<0.05).Conclusion HR-MRI has a higher consistency in diagnosing staging T of rectal cancer compared to MSCT and pathological di-agnosis results,and the consistency of the two methods in diagnosing staging N is comparable.Combined diagnosis of lymph node metastasis can improve accuracy and sensitivity.

Abstract:Objective To explore the clinical value of contrast-enhanced ultrasound(CEUS)combined with serum MicroRNA-9-5p(miR-9-5p)and MicroRNA-214-5p(miR-214-5p)in the diagnosis of benign and malignant breast nodules.Methods Totally,121 breast nodule patients who underwent CEUS examination were assigned into benign group(57 cases)and malignant group(64 cases)based on pathological results.Real-time fluorescence quantitative PCR was applied to determine the levels of serum miR-9-5p and miR-214-5p.ROC curve was applied to analyze the diagnostic efficacy of serum miR-9-5p and miR-214-5p levels for malignant breast nodules.Kappa test was applied to analyze the consistency between CEUS and serum miR-9-5p,miR-214-5p alone or in combination in the diagnosis of malignant breast nodules and pathological results.Results The malignant group had a higher number of nodules,higher peak intensity(PI)and higher serum miR-9-5p levels than the be-nign group,and a lower percentage of patients with early/chronological time to top(TTP),mean transit time(MTT),serum miR-214-5p levels and time to regression than the benign group.In the malignant group,CEUS was characterized by high en-hancement,unclear enhancement borders,irregular enhancement shape,and radial enhancement(P<0.05).ROC curve results showed that the AUC of serum miR-9-5p and miR-214-5p for diagnosing malignant breast nodules was 0.879 and 0.837,respec-tively.The consistency between CEUS and serum miR-9-5p,miR-214-5p alone or in combination for the diagnosis of malignant nodules and pathological results showed Kappa values of 0.669,0.622,0.553,and 0.857.The specificity,accuracy,and posi-tive predictive value of CEUS combined with serum miR-9-5p and miR-214-5p in distinguishing malignant breast nodules were higher than those of CEUS,miR-9-5p,and miR-214-5p alone(P<0.05).Conclusion The expression level of serum miR-9-5p increases and the expression level of miR-214-5p decreases in patients with malignant breast nodules.CEUS combined with se-rum miR-9-5p and miR-214-5p has high diagnostic value in distinguishing between benign and malignant breast lesions.

Abstract:Objective To investigate the impact of coilshim technology on the image quality of cervical segmented readout echo-planar diffusion-weighted imaging(RESOLVE-DWI).Methods Thirty-three patients underwent cervical MRI.Both RESOLVE-DWI and coilshim-RESOLVE-DWI sequences were performed.The image quality of both DWI sequences was subjec-tively and objectively evaluated at nasopharynx,oropharynx,hypopharynx and thyroid levels.Then statistical analysis was per-formed.Results Subjective scores showed that the coilshim-RESOLVE-DWI group had significantly higher overall image qual-ity scores and fat signal intensity scores compared to the RESOLVE-DWI group(P<0.05).The coilshim-RESOLVE-DWI group had slightly higher image susceptibility artifact scores,image distortion scores,and normal tissue structure display scores at dif-ferent levels of the neck region than the RESOLVE-DWI group,but the differences had no statistically significant(P>0.05).Ob-jective analysis revealed the coilshim-RESOLVE-DWI group demonstrated significantly superior SNR,CNR at four levels,and fat signal intensity at the nasopharynx,oropharynx and thyroid levels compared to the RESOLVE-DWI group(all P<0.05),while fat suppression effect at the oropharynx level had no statistically significant(P>0.05).Conclusion Compared with RESOLVE-DWI,combined with coilshim technique can significantly improve the overall image quality and the fat suppression effect of the cervical region,demonstrating clinical potential.

Abstract:Objective To explore the diagnostic value of whole brain quantitative segmentation based on artificial intelli-gence software MRI and brain region volume in early cognitive impairment of patients with small cerebral vascular disease.Methods A total of 135 patients with CSVD were selected,including 71 with cognitive impairment and 64 without cognitive im-pairment.The U-AI artificial intelligence software was used for quantitative brain segmentation to analyze the differences in brain region volumes between the two groups,and the ROC curve was drawn to analyze the diagnostic value of each brain region vol-ume for cognitive impairment in CSVD patients.Results The relative volumes of the cerebrospinal fluid,periventricular cere-brospinal fluid,third ventricle,choroid plexus and lateral ventricle brain regions in the cognitive impairment group were larger than those in the control group,while,the relative volumes of the gray matter,white matter,hippocampus,thalamus,precen-tral gyrus and superior frontal gyrus brain regions were smaller than those in the control group,with statistically significant dif-ferences(all P<0.05).The relative volumes of the cerebrospinal fluid,periventricular cerebrospinal fluid,hippocampus,white matter and lateral ventricle brain regions were independent influencing factors for cognitive impairment in CSVD patients(all P<0.05).The relative volume of the hippocampus had the highest diagnostic value for early cognitive impairment in CSVD patients(AUC=0.891),with sensitivity of 70.3%and specificity of 84.5%.Conclusion Quantitative brain volume by MRI has certain diagnostic value for early cognitive impairment in CSVD patients,with the diagnostic efficacy of hippocampus volume being the best.

Abstract:Objective To explore the application effect of MRI gradient spin echo-intravoxel incoherent motion(GRASE-IVIM)technique in testicular imaging.Methods A total of 47 patients who underwent testicular MRI examination were se-lected.Both the routine echo planar imaging-intravoxel incoherent motion(EPI-IVIM)and GRASE-IVIM sequence scans were performed.Subjective evaluation and objective analysis were carried out for the images of the two sequences.The subjective evaluation was conducted by two radiologists using the 4-point method.For the objective analysis,parameters such as the signal-to-noise ratio(SNR)and distortion rate(DR)of the images were calculated.Results The excellent rates of the subjective scores of the images of the EPI-IVIM and GRASE-IVIM sequences were 74.5%and 95.7%,respectively.The excellent rate of the GRASE-IVIM sequence was higher than that of the EPI-IVIM sequence,and the difference was statistically significant(all P<0.01).The DR and SNR of the EPI-IVIM sequence were higher than those of the GRASE-IVIM sequence,and the differences were statistically significant(P<0.01).There were no significant differences in other parameters between the groups(P>0.05).Conclusion Compared with the EPI-IVIM sequence,the GRASE-IVIM sequence can reduce susceptibility artifacts,decrease the distortion rate,improve the image quality,which has a higher clinical application value.

Abstract:Objective To analyze the research progress in the field of nuclear medicine nursing in China using Cite Space vi-sualization software.Methods China Knowledge Network database was used to search for research literature related to nuclear medicine nursing from 1993 to 2024.Then,we screened and extracted the literature information,and applied Cite Space soft-ware to analyze the included literature in terms of authors'cooperation,issuing institutions,keyword co-occurrence,and key emergence analysis.Results A total of 491 Chinese literatures were screened,with an overall fluctuating upward trend in the number of publications.Authors and research institutions lacked cross-regional and interdisciplinary cooperation.Combining with the graphical analysis of high-frequency keywords,keyword co-occurrences,keyword clustering,and keyword timeline,the hot-spots and cutting-edge research contents of nuclear medicine nursing were categorized into the three stages of exploration,devel-opment,and in-depth.Conclusion The research on nuclear medicine nursing in China has undergone an evolution from stan-dardizing basic nursing operations to improving nursing service quality.The research focus has gradually shifted from technical operations to meeting the comprehensive needs of patients and deepening personalized nursing plans.

Abstract:Objective To explore the value of MRI in assessing postoperative recovery following arthroscopic repair of rotator cuff tears.Methods 45 patients with rotator cuff teas undergoing arthroscopic repair underwent shoulder MRI examinations both preoperatively and at 3-6 months postoperatively.The preoperative MRI findings regarding tear extent were compared to evaluate recovery outcomes.Results Preoperative MRI demonstrated intact tendon continuity in 43 cases,among which 6 cases showed normal thickness without abnormal signals,19 case showed normal thickness with abnormal signal,and 18 cases exhibited reduced thickness with abnormal signal.2 cases exhibited postoperative re-tears.Conclusion Postoperative MRI demonstrates high clinical utility by assessing tendon continuity restoration,thickness,and signal characteristics in rotator cuff repair patients.

Abstract:Objective To explore the clinical diagnostic value of echocardiography combined with serum Asprosin and Tenascin-C in coronary atherosclerotic heart disease(CHD)complicated with silent myocardial ischemia(SMI).Methods A total of 149 suspected CHD patients with SMI admitted to our hospital were regarded as the study subjects,and were separated into an SMI group(n=117)and a non SMI group(n=32).ELISA was applied to detect serum levels of Asprosin and Tenascin-C.Multivariate logistic regression model was applied to analyze the factors associated with SMI in CHD patients.ROC curve was ap-plied to analyze the diagnostic value of echocardiography combined with serum Asprosin and Tenascin-C for SMI in CHD pa-tients.Results The left ventricular end diastolic volume(LVEDV)and left ventricular end systolic volume(LVESV)in the SMI group were obviously higher than those in the non SMI group(all P<0.05),and the left ventricular ejection fraction(LVEF)was obviously lower than that in the non SMI group(P<0.05).The serum levels of Asprosin and Tenascin-C in the SMI group were obviously higher than those in the non SMI group(all P<0.05).Multivariate logistic analysis showed that LVEDV(OR=1.437),LVESV(OR=1.525),LVEF(OR=0.843),Asprosin(OR=1.852),and Tenascin-C(OR=1.714)were all influencing factors for SMI in CHD patients(all P<0.05).ROC results showed that the AUC of echocardiography,serum Asprosin,and Tenascin-C for diagnosing CHD complicated with SMI was 0.767,0.737,and 0.780,respectively.The AUC of echocardiography combined with serum Asprosin and Tenascin-C for diagnosing CHD complicated with SMI was 0.898,and the AUC was obviously higher than AUC of echocardiography,serum Asprosin,and Tenascin-C(Z=2.947,3.289,3.235,all P<0.05).Conclu-sion Serum levels of Asprosin and Tenascin-C are higher in patients with CHD complicated with SMI.The combination of echo-cardiography with serum Asprosin and Tenascin-C has high diagnostic value for CHD complicated with SMI.

Abstract:Objective To analyze the imaging characteristics of 99Tcm-MDP SPECT/CT in SAPHO syndrome and to investi-gate the diagnostic value of this method in SAPHO syndrome.Methods The 99Tcm-MDP SPECT/CT data of 7 patients with SAPHO syndrome were retrospectively analyzed and the bone and joint involvement of SAPHO syndrome were observed.Results All 7 patients had multisite involvement,anterior chest wall involvement and spine involvement were most commonly seen.Among 7 cases,there were 12 sites of bone erosion and joint bone resorption,28 sites of hyperostosis and osteosclerosis,and 12 sites of narrowing of joint space and joint fusion.Conclusion SAPHO syndrome can cause multiple site involve-ment,99Tcm-MDP SPECT/CT can help improve the diagnostic accuracy by reducing the omission of lesions and providing relevant imaging information.

Abstract:Objective To investigate the clinical value of echocardiography in diagnosing partial pulmonary venous connec-tion anomaly(PAPVC),to analyze the causes of missed and misdiagnosis.Methods The clinical data of 183 cases of PAPVC confirmed by surgery or CTA were selected,and the preoperative echocardiographic features were compared and analyzed with the CTA or surgical findings,and in-depth analyses were performed for the missed diagnosis,misdiagnosis,and subtyping,and the key points of echocardiographic diagnosis of this disease,and diagnostic techniques for different subtypes were summarized.Results Among 183 children with PAPVC,58.5%(107/183)were supracardiac,36.6%(67/183)were intracardiac,3.3%(6/183)were subcardiac,and 1.6%(3/183)were mixed.The echocardiographic diagnosis was correct in 158 cases,with a diag-nostic compliance rate of 86.3%,21 cases were missed,and 4 cases were misdiagnosed,with a rate of 13.7%.11 cases were missed due to the combination of multiple congenital cardiac malformations and neglect of pulmonary vein scanning,5 cases were missed due to heavy lung gas,which could not be clearly shown the traveling shape of each pulmonary vein,4 cases were missed due to insufficient knowledge of the disease,and 1 case was missed because the child was too old for subxiphoid.Among the 4 cases of misdiagnosis,3 cases of intracardiac PAPVC were misdiagnosed as secondary foramen ovale septal defect and 1 case of supracardiac PAPVC was misdiagnosed as left atrial main vein.Conclusions Echocardiography has an important diag-nostic value for PAPVC.Meanwhile,analyzing the reasons for missed diagnosis and misdiagnosis is necessary to improve the di-agnostic accuracy of this disease,which has an important clinical value for the timing and method of surgery as well as the assess-ment of patients'prognosis,thereby avoiding secondary surgery for patients.

Abstract:Objective To investigate the diagnostic value of magnetic resonance imaging-estimated proton density fat frac-tion(MRI-PDFF)technology and liver function parameters for metabolic dysfunction associated fatty liver disease(MAFLD).Methods A total of 91 patients diagnosed with fatty liver disease were enrolled and categorized into a MAFLD group(n=61)and a control group(n=30).The hepatic proton density fat fraction(PDFF)values and liver function parameters were compared between the two groups.The differences of hepatic PDFF values and liver function tests between the two groups were compared.Results The mean PDFF value of segment S1 to S8 in MAFLD group was(15.94±8.64)%to(20.05±8.89)%,and that in the control group was(16.37±9.61)%to(20.28±10.66)%.No significant difference in PDFF values among liver segments be-tween the two groups were found(all P>0.05).The mean PDFF values of the left hemi-liver,right hemi-liver and whole liver in the MAFLD group were(17.59±8.57)%,(19.37±8.88)%,and(18.44±8.56)%,while,those in the control group were(17.64±9.87)%,(19.57±10.32)%,and(18.60±9.98)%,respectively.No significant difference in PDFF values of left hemi-liver,right hemi-liver and whole liver between the two groups were found(all P>0.05).There were 20,10 and 17 cases of abnormal liver func-tion tests in MAFLD group,which were higher than 7,1 and 9 cases in the control group.Conclusion No significant difference in liver fat accumulation pattern is found in Couinaud segments,hepatic lobes and whole liver level between fatty liver disease pa-tients with MAFLD and control group.Patients with MAFLD may have a higher proportion of elevated ALT,AST and GGT.

Abstract:Objective To investigate the diagnostic value of dual-source CT virtual non-calcium technology for bone marrow edema in knee osteoarthritis.Methods 36 patients diagnosed with knee osteoarthritis and who underwent knee CT and MRI ex-aminations were selected.After the examination was completed,the CT data were imported into a Siemens workstation,and the bone marrow edema mode was used to obtain virtual non-calcium(VNCa)images.Using the results of the knee MRI T2WI fat-suppressed images as the gold standard,two radiologists measured the edema area on the VNCa images under different Rel.Ca(relative calcium ratio,Rel.Ca)values.The receiver operating characteristic(ROC)curve was used to compare the diag-nostic efficacy of dual-source CT virtual non-calcium images for knee bone marrow edema under different Rel.Ca values.Results When Rel.Ca values were 1.39,1.49,and 1.59,the Youden indices were 0.468,0.746,and 0.658,respectively.Us-ing the MRI results as a reference,the intraclass correlation coefficients for the measurements of edema area on VNCa images by the two radiologists under different Rel.Ca values were 0.467,0.815,and 0.640,respectively,and the areas under the ROC curve were 0.579,0.857,and 0.643,respectively.Conclusion When the Rel.Ca value is 1.49,the diagnostic efficacy of dual-source CT VNCa images for bone marrow edema in knee osteoarthritis is the best.

Abstract:[Abstact]Objective To evaluate the application of a dual-dimensional nursing model in the interventional treatment with biodegradable occluders of children with congenital heart disease.Methods Ten children with CHD treated with biodegradable occluders were included,comprising eight with ventricular septal defect(VSD)and two with patent foramen ovale(PFO).A dual-dimensional intraoperative nursing model was de-veloped,integrating standardized procedural protocols with individualized strategies tailored to the specific characteristics of VSD and PFO.This approach aimed to optimize nursing support,enhance procedural suc-cess,and reduce complication rates.Results All procedures were successfully completed(100%success rate),with no major complications observed during six months of follow-up.Conclusion Implementing a dual-dimensional nursing model that combines standardized procedures with individualized strategies can enhance.

Abstract:Objective To explore the ultrasound features of pseudomyxoma peritoneum(PMP).Methods We selected 55 cases of peritoneal pseudomyxoma confirmed by pathological examination,and analyzed their clinical,pathological,and ultra-sound manifestations.Results Among the 55 cases,there were 17 cases of malignant primary tumors and 38 cases of benign primary tumors.A fluid dark area in the abdominal cavity was detected by ultrasound,which was shown diffuse distribution or lo-calized wrapping.Many strong vocal cords were visible inside,appearing as grid like,dense point like,or clustered echoes,and no intestinal tube floating was observed.Among them,59 mucinous masses with diameters ranging from 2.3 cm to 31.0 cm were detected in the abdomen and pelvic cavity of 36 cases.Mucinous ascites and cystic masses were shown low echogenicity,and Color Doppler Flow Imaging(CDFI)showed abundant blood supply in the parenchymal part of the masses.32 cases had a large amount of mucinous ascites,23 cases had a small amount of mucinous ascites,27 cases had extensive thickening of the perito-neum,28 cases had reticular septa in the mucus,35 cases had a"cake shaped"omentum,31 cases had honeycomb septa in the cystic mass,27 cases had"scallop like"imprints on the edges of the liver,spleen,and pancreas,and 5 cases had retroperito-neal lymph node enlargement.Conclusion PMP mucinous ascites is extensive,with US showing multiple honeycomb or solid mucinous masses in the abdominal cavity,poor acoustic transmission within,and thickening of the omentum in cord-like,clump-like,or pancake-like patterns.The surrounding parenchymal organs exhibit serrated or"scallop-like"depressions at the edges as characteristic features.

Abstract:Objective To evaluate the application value of the"tri-low"technology based on dual-source CT CARE kV in coronary computed tomography angiography(CTA).Methods A total of 300 patients suspected of having coronary heart dis-ease and undergoing coronary CTA were selected.These patients were divided into two groups,A and B,based on whether they used CARE kV technology.Both groups were utilized CARE Dose 4D automatic milliampere scanning technology.The study com-pared the subjective and objective image quality and radiation dose of the coronary arteries between the two groups.In Group A,the iodine contrast agent flow rate was adjusted according to the CARE kV tube voltage value:3.5 mL/s at 70 kV,with a 0.5 mL/s increase for every 10 kV increase.The contrast agent injection dose was calculated as the contrast agent flow rate multiplied by 13 seconds.In Group B,the contrast agent injection dose and flow rate were determined based on the patient's weight:the con-trast agent injection dose was the patient's weight(kg)×0.8 mL divided by the contrast agent flow rate 13 mL/s.The study com-pared the contrast agent injection doses and flow rates between the two groups.Results The radiation dose in Group A was lower than that in Group B,with a statistically significant difference(P<0.05).The subjective image quality score in Group A was higher than that in Group B,but the difference was not statistically significant.The objective image quality score in Group A was higher than that in Group B,and the contrast agent injection dose and flow rate in Group A were lower than those in Group B(all P<0.05).Conclusion The"tri-low"technology based on dual-source CT CARE kV can significantly reduce the effective radiation dose of subjects and reduce the injection dose and flow rate of contrast agent during coronary artery CTA examination.

Abstract:Objective To explore the relevance of 3D-STI in a clinical context technology combined with serum levels of SAA and β-defensin-3 in evaluating patients with ST segment elevation myocardial infarction complicated with chronic obstruc-tive pulmonary disease(COPD)and pulmonary infection.Methods A total of 40 patients with ST segment elevation myocar-dial infarction and COPD were selected as the study subjects.Patients with concomitant pulmonary infections were included in the study group,while,patients without pulmonary infections were included in the control group.Using 3D-STI technology and combined detection of serum levels of SAA and β-defensin-3 in patients,we compared the differences between the two groups and evaluated the clinical significance of 3D-STI technology combined with serum levels of SAA and β-defensin-3 in evaluating patients with ST segment elevation myocardial infarction combined with COPD and pulmonary infection.Results There were significant differences in terms of overall strain(GS),overall circumferential strain(GCS),overall longitudinal strain(GLS),and overall radial strain(GRS)in the study group with the control group(all P<0.05).The serum levels of SAA and β-defendin-3 in the study group were significantly different from those in the study group(all P<0.05).Conclusion The combination of 3D-STI technology and serum levels of SAA and β-defensin-3 is of great clinical significance for evaluating patients with ST segment elevation myocardial infarction combined with chronic obstructive pulmonary disease and pulmonary infection.

Abstract:Objective To explore the value of BrafV600E gene detection combined with shear wave elastography(SWE)in dif-ferentiating benign and malignant thyroid nodules and predicting the invasiveness of malignant nodules.Methods A total of 120 patients with thyroid nodules who underwent thyroidectomy were selected.Braf V600E gene detection combined with SWE ex-amination was performed before the operation.According to the postoperative pathological examination results,among the 120 pa-tients,64 cases were malignant nodules and 56 cases were benign nodules.According to the metastasis of cervical lymph nodes,patients with malignant nodules were divided into the metastasis group(n=35)and the non-metastasis group(n=29).Logistic re-gression was used to analyze the relationship between the BrafV600E gene and SWE parameters and cervical lymph node metastasis of malignant thyroid nodules.Then,we calculated the area under the receiver operating characteristic curve(AUC),sensitivity and specificity,and evaluated the discriminatory value of BrafV600E gene combined with SWE for benign and malignant thyroid nodules and the predictive value for cervical lymph node metastasis of malignant nodules.Results The positive rate of Braf V600E gene mutation in the malignant group was 68.75%,significantly higher than 1.79%in the benign group,and the difference was statistically significant(P<0.05).The maximum Young's modulus(Emax)and average value(Emean)of nodules in the region of interest in the malignant group,as well as the elastic ratio(Eratio)of thyroid nodules to surrounding normal thyroid tissue were sig-nificantly higher than those in the benign group,and the differences were statistically significant(P<0.05).The sensitivity and AUC of BrafV600E gene combined with SWE in diagnosing malignant thyroid nodules were significantly higher than those of indi-vidual indicators(P<0.05).The positive rate of BrafV600E gene mutation and the Young's modulus Emax,minimum value(Emin),Emean and Eratio values of nodules in the region of interest in the metastasis group were significantly higher than those in the non-metastasis group,and the difference was statistically significant(P<0.05).BrafV600E gene,Emax and Eratio were independent risk factors for cervical lymph node metastasis of malignant thyroid nodules(P<0.05).The sensitivity and AUC of BrafV600E gene com-bined with SWE in diagnosing cervical lymph node metastasis of malignant thyroid nodules were significantly higher than those of individual indicators(P<0.05).Conclusion The BrafV600E gene detection combined with SWE has a relatively high value in differentiating benign and malignant thyroid nodules,and has a certain predictive value for the invasiveness of malignant nod-ules,which can provide a reference basis for clinical diagnosis and treatment.

Abstract:Objective To explore the clinical data of 12 patients which had pneumatosis cystoides intestinalis(PCI)relevant to α-glucosidase inhibitor and targeted drugs,and to investigate the pathogenesis,clinical characteristics,endo-scopic and imaging manifestations of PCI.Methods 12 patients with PCI were selected in this work.Their clinical char-acteristics were analyzed,and the imaging features such as the scope,shape and size,as well as the treatment and prognosis were observed.Results Among the 12 patients,eight cases had diabetes and acarbose history.One case had gastric cancer and one case had lung cancer,both of them were received surgery and targeted drugs therapy.One case had a history of chronic bronchitis,nephrotic syndrome and rituximab treatment.One case with prostate cancer had been treated with targeted drugs.The endoscopic manifestations of PCI were uneven particles of colonic mucosa,blister-like changes,smooth surface and soft touch and the imaging findings were gas accumulation in different areas of colon or small intestinal wall,the gas forms were honeycomb,grape and beaded dense distribution.8 patients were complicated with free gas of varying sizes in the abdominal cavity at the same time.Conclusion The formation of PCI is related to many fac-tors.When patients underwent targeted drugs and α-glucosidase inhibitor have gastrointestinal symptoms such as abdominal distension,abdominal pain and diarrhea,the possibility of PCI should be aware of.Endoscopy or CT can be performed for definite diagnosis.