1Advance of improvment of the prediction on cardiovascular toxicity in the drug developmentWANG Ju-feng2753-27582Analysis and enlightenment of the main problems of data integrality in FDA warning lettersYANG Zhu-ren, ZHAO Shuang-chun, ZHAO Hong-ju2759-27633Bezlotoxumab——a new human monoclonal antibody for the prevention of Clostridium difficile infectionLI Chun-xing, LIU Hua2764-27664Sugammadex: a novel selective muscle relaxant antagonistZHAO Ying, JIANG Lu-yang2767-27715Reproductive and developmental toxicity of the marketed anti-diabetic agents for type 2 diabetic mellitusYU Shan-shan, YIN Hua-jing, ZHOU Heng, WANG Qing-li, HU Xiao-min2772-27796Research progress on continuous production and process control technology of oral solid dosage formsTONG Yong-tao, GAO Chun-hong, GAO Chun-sheng2780-27877Absorption mechanism of kirenol and pharmacokinetic analysis of its sustained-release pellets in beaglesHE Dong-mei, GUAN Shi-xia, FU Hong-zheng, LU Shu-fan, ZHOU Xiang-ping2788-27938Factors affecting the efficacy of clopidogrel and its metabolismSHENG Guo-tai, XU Xiu-xiu, GE Yu-zhi2794-27989Pathogenesis of Alzheimer's disease and the therapeutic mechanism of natural polyphenolsLIU Shi-xian, MAO Lin-fei, YU Fan, ZHANG Yu-bo, GAO Xiao-ling2799-280410Application progress of nanomedicines in the treatment of strokeLIANG Xin-tong, LI Qiang, XUE Ming, ZHAO Yu-ming2805-281111Research progress of immune checkpoint inhibitors in clinical treatmentDU Ping, LIU Li-hong2812-281712Therapeutic effect, nerve function, CRP level analysis of butylphthalide and sodium chloride injection combined with edaravone in the treatment of new-onset cerebral infarctionYUAN Qing-fang, LI Xin-xin, ZHANG Jian-ping, DONG Wan-li2818-282113Clinical study of Safflower yellow pigment on the improving the cerebral perfussion in patients with acute cerebral infarctionLIU Qing, HUANG De-hong, HUANG Jian-hong, WANG Cheng-yin, XU Xing-yi, WENG Xu-liang, LIN Qiao-yang2822-282514Clinical observation of retention enema with Compound Cortex Phellodendri Ye Paints on type ⅢA chronic prostatitisZHU Hai, WENG Bo-wen, ZHAO Hai-jun, DENG Jun, ZHANG Yan, LI Mo-nong, WU Shuai, WANG Peng, QI Hai-yan2826-282915Clinical observation of Compound Cortex Phellodendri Fluid wet dressing in the treatment of hot and humid bet type anal eczemaBAI Ke-yun, GU Chao2830-283316Synthesis of verubecestat as a BACE inhibitorRAO Yan, GUO Ya-jun, ZHU Xue-yan, LIU Xiang-kui2834-283917Effects of total saponins from rhizoma dioscorea nipponica on biomarkers in serum of gouty arthritis ratsLIN Fang-fang, LIU Shu-min, ZHOU Qi, ZHANG Na2840-284518Methotrexate sustained-release implants for delay of sarcoma recurrence in miceLIU Xiu-xiu, GAO Li, XIA Lun-yang, XU Jian-jian, LIAO Chen-zhong2846-285219Study on preparation and dissolution of trollius suppositoryZHAI Yue, LI Yuan-yuan, WANG Zhong-yan2853-285820Preparation and release of huperzine A precursor liquid crystal formulationsGUO Si, ZHOU Meng-meng, PAN Qian-wen, LI Li, LIU Hong, LUO Liang2859-2863