Reproductive and developmental toxicity of the marketed anti-diabetic agents for type 2 diabetic mellitus
YU Shan-shan
YIN Hua-jing
ZHOU Heng
WANG Qing-li
HU Xiao-min
Abstract：The aim of this review is to provide reference information for the non-clinical safety evaluation and reproductive toxicity risk management in clinical tirals for anti-diabetic agents.The reproductive and developmental toxicity information as well as the safety ranges of the representative anti-diabetic agents for type 2 diabetes mellitus on the market were summarized based on the labeling and review documents obtained from the official website of the US Food and Drug Administration and other regulatory agencies.
Keywords：anti-diabetic agents for type 2 diabetes mellitus (T2DM)reproductive and developmental toxicitysafety rangerisk management
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：8( 2772-2779 )