1Analysis of judicial precedent of traditional Chinese medicine patent-related creative lawZHANG Chao-lei, ZHAO Liang, BIAN Zhi-jia, SHI Xiao-rong, LIU Yan-fang, SUN Hai-yan, CHEN Yun-hua129-1332A brief analysis of the influence of implementation of work program for the Reform of Classification of Chemical Medicine Registration on the research and development of chemical medicines in China and the countermeasuresTANG Jin-rui, SUN Min, XU Li-li134-1373Discussion about internal standards in LC-MS for bioanalysisDU Xiao-lin, HUANG Juan, LIU Xiao-juan, YONG Xiao-lan138-1414An analysis of the registration and approvals for class Ⅰ of innovative drug during 2005-2016 in ChinaFAN Yu-lu, CHEN Yu-wen142-1465Advances in formulation approach and action targets of novel antiviral drugsHOU Guan-hua, QIU Rui-gui, GAO Chun-sheng147-1536Research progress of phenylketonuria and its releveant treatmentNIU Rui-qing, FENG Wen-hua154-1587Current status and new development of drugs for asthma and chronic obstructive pulmonary diseaseYU Yong, NING Bao-ming, SHU Hong, WEI Ning-yi, HOU Shu-guang159-1668Inhibiting effect of establishment of peripheral hyperinsulinemia on endogenous insulin secretion when using euglycemic clamp techniqueLIU Hui, YU Hong-ling, LIU Jia-li, LI Jia-qi, TAN Hui-wen, YU Ye-rong167-1729Clinical observation of recombinant human erythropoietin on chemotherapy-induced anemia in patients with gastrointestinal cancerZHAO Cheng-min, HUANG Dai-fa, ZHANG Li-hui, CAO Yu-hua, CHE Hai-long173-17710Investigation of metabolic stability and metabolic enzyme phaenotypes of anti-tumor compound HK-7 in different species of liver microsomes by UPLC-MS/MSXIA Yuan-yuan, YANG Ju-qin, ZHU Yi-ting, CHEN Ying-jie, TANG Ming-hai, WAN Li178-18311Effects of valsartan on podocyte autophagy in rats with diabetic nephropathyWANG Xiao-dan, GAO Li-hui, NIU Yan-fen, LIN Hua, WANG Jin-wen, LI Ling184-18912Effect of baicalin on the expression of NLRP3 inflammsome and inflammatory factors in monosodium urate-induced RAW264.7 macrophagesWEN Xue-ping, LIU De-jun, PEI Yi-xue, XU Ling-yun190-19413Experimental study of the effects of SKI on peritoneal fibrosis relating to peritoneal dialysisWANG Yu-xun, AN Ya-chen, JIANG Yan-ru, LI Yan-zheng195-20214Improvement of synthetic route of saxagliptinCAO Wen-ting, HE Huan, ZHANG Qiao-yan, ZHANG Yong203-20615Design and evaluation of dual targeting multifunctional nanocarrierSONG Xiao-yan, WANG Xiao-ying, QI Meng-jiao, DONG Xue, WANG Kai-li, GUO Chun-jing, CHEN Da-quan207-21316Preparation of pantoprazole sodium bioadhesive tabletsSUN Tao-li, JIANG Mei, JIANG Yao, LIU Wei-ping, WU Zhu, WEI Quan-min, TANG Jing, WANG Jian-fen, MA Ning214-21917Preparation and in vitro release of asenapine maleate-loaded microspheresZHOU Xiang-ping, HE Dong-mei, YANG Juan, MO Jian-mei, CHEN Xin-tong, GUAN Shi-xia220-22418Determination of equilibrium solubility and apparent oil/water partition coefficient of berberine α-hydroxy β-decanoylethyl sulfonateLIU Man, LI Hui, DING Jin-song225-22819Efficacy and safety of PD-1 antibody/PD-L1 antibody versus docetaxel in non-small-cell lung cancer:a Meta-analysisWAN Qiu, YANG Yang, LI You-lun229-23520Detection and evaluation of dasatinib-induced respiratory system ADR signals in post-marketing experienceTIAN Ya-lan, BIAN Gui-zhi, CAO Pei, ZHANG Zhi-yong236-241 