1The Platform Technology Designation Program for Drug Development Guidance for Industry of the United States and its implications for the regulation of cell and gene therapy in ChinaMA Qiao-ning, SUN Tan-lin, WANG Wen-ya337-3402Construction and considerations on efficacy evaluation indicator system of Chinese medicine syndromeWANG Jian-xin, DAI Xin-yue, SUN Ming-yue, LV Xing, GUO Man-ping, ZI Ming-jie, YANG Qiao-ning, GAO Rui341-3453Analysis of the drug patent term extension provisions in the context of the new Detailed Rules for the Implementation of the Patent Law of the People's Republic of China and Patent Examination GuidelinesSUN Ming-ming346-3514Problems and thoughts on clinical data in the filing of traditional Chinese medicine preparations using traditional techniques in medical institutionsLI Si-qi, ZHOU Meng-yue, YANG Fang-fang, ZHANG Zhi-yu, PAN Ding-ju352-3575Research on defense of uncertainty to patent infringement of generic drug commissioned developmentJIN Chun-yang, HE An-qi358-3636A selective inhibitor of cyclin-dependent kinases 4/6,ribociclib,for the treatment of breast cancerLI Yan, CUI Ying-jie, LIU Juan-juan, ZHAO Hui, WANG Zhen-zhen, ZHOU Yi, ZHANG Jing364-3697Exploration of the full life cycle management of drug guidance by the U.S.FDA and its inspiration to ChinaSUN Tan-lin, MA Qiao-ning, XU Zhen-yu370-3768Evaluation and optimization of anti-breast cancer effect of dendritic cell vaccine derived from cord blood CD34+hematopoietic stem cells in vitroWANG Miao, XIE Hui-ping, YAN Ke-qing, CUI Hong-fei, LI Wei, ZHANG Zhi-fei, JIN Yuan-yuan377-3859Research progress in organ-on-a-chip and its application in the development of new drugsZHANG Shi-long, LE Le, LIANG Xu-rui, ZHANG Xiao-wei, ZUO Zhi-qiang, ZHANG Tao386-39310The application of error-corrected duplex sequencing in genetic toxicity and carcinogenicityCUI Wen-teng, ZHENG Ming-lan, ZHOU Chang-hui, HE Wei-wei, FANG Ya-li, FENG Tian-yi, DU Hong-li, CHANG Yan394-40011Effects of trace elements supplementation for parenteral nutrition on serum trace element levels in preterm low birth weight infantsGU Ying-fen, FU Huan-huan, JIA Xue-qi, PAN Li-ya401-40612A study on the preventive and therapeutic effects of Xiang Huo Spray on upper respiratory tract infections in miceLI Ting, YAN Hong, GONG Lv-dong, ZHONG Cheng-zhi, LIN Rui-chao, ZHU Gao-qian, SUN Wen-qiang, WU De-song, GUO Yan407-41313Preparation and quality evaluation of lansoprazole enteric orally disintegrating tabletsHE Yan-ni, JIANG Chuan-zhen, WU Xiu-ning, WANG Dong-kai414-41814Simultaneous determination of ten chemical components in Menggen Vos-18 pills by method of quantitative analysis of multi-components by single markerSU Duna-buqi, HE Ye, MO Ri-gen, HAO Jun-sheng, HAI Jin, WANG Xiu-lan419-42515Anti-aging effect of icariin on caenorhabditis elegansWANG Kai-he, WANG Shi-feng, MU Lei-xin, LIU Tian, KE Cai-yi, XU Guang, MA Qun426-43216Mining and analysis of vemurafenib adverse event signals based on the FAERS databaseLIU Jing-ru, WANG Shi-heng, CHEN Min, LU Cheng-can433-43717A review of pharmacoeconomic evaluation on oral and intravenous dosage forms of drugs with the same chemical name or categoryLIU Chang, WEI Jia-yin, WU Yao, WANG Fang-xu, SUN Shuang, TAO Li-bo438-44318Signal mining and analysis of adverse drug events of intravenous and oral iron preparations in some cityMA Si-jia, LI Xing-qiao444-448 