1Chinese expert consensus on comprehensive management of patients with cardiovascular-kidney-metabolic syndrome(reprinted)The Editorial Committee of Chinese Journal of Cardiovascular Research, Heart-Renal-Metabolic Disease Prevention and Treatment Group,Future Biomedical Engineering Branch,China Future Research Association, Xia Jinggang, Yuan Mingxia, Cai Xiaoling, Wang Zhijian, Zheng Bo, Feng Xue, Zhang Ling, Huang Xiaoqin, Tong Zhu, Jia Linpei, Wang Hong, Liu Guoyou, Qu Zheng, Ji Xunming, represent the consensus expert groupGuideline and recommendation1-362Expert consensus on the diagnosis and treatment of esophageal and gastric variceal rupture bleeding in cirrhotic portal hypertension(2025 edition)(reprinted)Chinese Society of Spleen and Portal Hypertension Surgery,Chinese Society of Surgery,Chinese Medical Association, Yang LianyueGuideline and recommendation37-453Application of the teaching model of combining three-dimensional(3D)printing technology with case-based learning(CBL)in clinical nursing education for intracranial aneurysmLu Yong, Wang Yao, Wang Jue, Yan Lihua, Wang FangOriginal Articles46-50,614Status and influencing factors for care readiness of family caregivers for patients with tracheotomy in neurosurgeryLi Ni, Wang Feng, Wang Hong, Luo HaiyanOriginal Articles51-555Evidence summary on central venous line management for parenteral nutrition in critically ill patientsSun Mingzhu, Shi Min, Xiang Luwei, Zhai Huaixiang, Li NingOriginal Articles56-616Modified technique for digifal subtraction angiography-guided transnasal intestinal obstruction catheterization and clinical efficacy analysisWang Zuxin, Chen Guo, Jiang HuaOriginal Articles62-657Status and influencing analysis of fecal incontinence and constipation in patients with ulcerative colitis in remissionZeng Yi, Zhang ZhimeiOriginal Articles66-718Research progress on the mechanisms and interventions of cardiac conduction block after transcatheter aortic valve replacementFan Jianhua, Xu HaixiangReview72-80