Evidence summary on central venous line management for parenteral nutrition in critically ill patients
Sun Mingzhu
Shi Min
Xiang Luwei
Zhai Huaixiang
Li Ning
Abstract：Objective To summarize the best evidence on the central venous line management for parenteral nutrition in critically ill patients at home and abroad.Methods Based on the"5 S"evidence pyramid model,we searched in a top-down order for practice guidelines,clinical decisions,evidence summaries,expert consensus,systematic evaluations,and original studies on infusion standardization,nursing care,and monitoring of complications for parenteral nutrition in critically ill patients.Two investigators independently assessed the quality of the included literature and integrated the evidence with the judgment of clinical experts.Results A total of 9 papers were included,including 2 clinical decisions,1 systematic evaluation,1 evidence summary,3 expert consensus,and 2 RCTs.Through literature reading and evidence integration,18 pieces of evidence were summarized in 5 areas:management and training,line selection,skin disinfection,use of drug delivery devices,and flushing and sealing tubes.Conclusion The summarized best evidence is to provide safe norms for parenteral nutrition therapy in critically ill patients.
Keywords：Intensive careParenteral nutritionEvidence
Publication Date：2025-03-20
Online Publishing Date：2025-11-20(First online date of this platform, not the publication date of the document)
Pages：6( 56-61 )