Research progress on the mechanisms and interventions of cardiac conduction block after transcatheter aortic valve replacement
Fan Jianhua
Xu Haixiang
Abstract：Transcatheter aortic valve replacement(TAVR)has become an effective treatment for high-risk patients with aortic stenosis(AS),but the occurrence of cardiac conduction block(CCB)after TAVR remains a clinical challenge.This review summarizes the latest research progress on the mechanisms,predictive indicators and management strategies of CCB after TAVR.Studies have shown that the occurrence of CCB after TAVR is related to multiple factors,including anatomical structure,valve type,preoperative electrocardiogram abnormalities,and intraoperative techniques.In terms of postoperative management,the use of temporary pacemakers has become a standard practice,and transitional pacemakers can effectively reduce unnecessary permanent pacemaker implantation.The indications for permanent pacemaker implantation should be comprehensively judged based on the type of conduction block,the patient's clinical manifestations,and cardiac function.Future research needs to further explore the long-term prognosis of CCB,the impact of new valve designs on the conduction system,and the construction of accurate predictive models,so as to provide the more precise and individualized treatment plans for prevention and therapy of CCB after TAVR and to improve the long-term prognosis of patients.
Keywords：Transcatheter aortic valve replacementCardiac conduction blockLeft bundle branch blockAtrioventricular blockPacemaker
Publication Date：2025-03-20
Online Publishing Date：2025-11-20(First online date of this platform, not the publication date of the document)
Pages：9( 72-80 )