1Selection of endpoints for efficacy in clinical trials of new drugsLIU Bing-lin2113-21202General considerations and issues of special concern about the nonclinical study of modified new drugsDAI Xue-dong, SUN Tao, HUANG Fang-hua, WANG Qing-li2121-21273Interpretation and thinking of contents of the application dossier for evaluation and approval of pharmaceutical excipients associated with drug productsREN Lian-jie, MA Yu-nan, JIANG Yu, ZHANG Ling-chao2128-21354Introduction and analysis of CDE's effort in solving backlog of generic drug registration applicationsCHEN Xin, HUANG Qing-zhu, WEN Bao-shu2136-21425Effects of manufacturing process and process control on related substances of synthetic peptide drugsHU Yu-xi, JIANG Yu, HAN Tian-jiao2143-21486Discussion on the supervision and management methods of drug clinical trials in ChinaGAO Jian-chao, HUANG Yun-hong, YANG Huan, GAO Chen-yan2149-21537Guideline on extrapolation of data from adults to pediatric population and relevant evaluation considerationsSUN Yan-zhe, GENG Ying, ZHAO De-heng, YANG Zhi-min2154-21588Research & development of Austedo (deutetrabenazine) : a case studyGAO Guang-hua, WANG Hai-xue2159-21659Reproductive toxicity profiles of direct-acting antiviral drugs for HCVYU Chun-rong, DA Hong-yuan, SHAN Xiao-lei, WANG Qing-li2166-217010Key points in the development of dermatology drugsZHANG Xing-yi, TIAN Na2171-217611Profile of GMP clearance for overseas manufacturers in AustraliaCHEN Fang2177-218012Analysis of the reproductive toxicity studies of new Chinese herbal drugs applied for registration in China in recent years and discussion of relevant issuesZHANG Xiao-dong2181-218413Strategic discussion on the overall thinking of developing quality standards of new Chinese medicinal prescriptionsZHANG Yong-wen2185-218914Common problems in the research of technology transfer of traditional Chinese medicine and some suggestionsHAN Wei2190-219215Guideline on clinical investigation of traditional Chinese medicinal and herbal medicinal products in the treatment of climacteric syndrome in women: supplement considerationsPEI Xiao-jing, YANG Na2193-219516A comprehensive evaluation strategy for chondrogenic differentiation of human mesenchymal stem cellsZHANG Ke-hua, LIU Jing, NA Tao, YUAN Bao-zhu2196-220317Advances in research on chemical constituents and genetic diversity of Aquilaria sinensis (Lour.) GilgLIN Dan, YAN Han-jing, LI Lei, HE Meng-ling2204-220818Absolute bioavailability of pazufloxacin mesilate capsule in healthy Chinese subjectsXIANG Jin, YU Qin, LIANG Mao-zhi, NAN Feng, QIN Yong-ping2209-221219Effect of cordycepin on apoptosis of human renal carcinoma cell line ACHN and its mechanismLIU Wen-si, SUN Ming-li, YU Zhao-jin, WEI Min-jie2213-221720Scutellaria Barbata flavonoids inhibit the abnormal generation of Aβ and NFT in brain and affect the related enzymes expression induced by composited Aβ in ratsHOU Xiao-chan, WANG Chong-zhi, WANG Zi-yi, ZHAO Wen-jing, GUO Ke, MA Shuai, WU Xiao-guang, SHANG Ya-zhen2218-2224 