Key points in the development of dermatology drugs
ZHANG Xing-yi
TIAN Na
Abstract：Most of the external-use dermatology drugs are half-solid preparations,which have the features such as multiphase,thermodymatic-unstability,numerous excipients and were developed through a complex optimization procedure.Some of them need a transdermal test to reveal their effects on the whole body,thus the evaluation method of dermatology drugs is quite different from the normal solid dosage forms and injectable medicines.In this article,the key points of the scientific development of dermatology dosage forms,the legal resource of excipients,the control of the impurities,the design and assessment of transdermal test,and the particularity of the stability test were summarized,interpreted and analyzed.
Keywords：dermatologyexternal drugstransdermal test
Publication Date：2017-01-01
Online Publishing Date：2026-08-14(First online date of this platform, not the publication date of the document)
Pages：6( 2171-2176 )