Ovarian immature teratoma combined with gliomatosis peritonei:report of a case
ZHOU Na
CAO Zhang
QI Jing
Abstract：Objective To explore the clinical and pathological characteristics, diagnosis, treatment, and prognosis of immature ovarian teratoma (OIT) combined with peritoneal glial tumor disease (GP). Methods A case of OIT combined with GP was collected, and its clinical and pathological features were analyzed. Results The patient was a young female. Grossly, the tumor showed a cystic-solid appearance, with the solid part mostly gray-white and soft, and some areas hard. The cystic part contained clear fluid, with some areas containing oil and hair. Scattered gray-white nodules were present on the surface of the omental tissue. Microscopically, the tumor was composed of mature three germ layer tissues, with a large number of mature neural glial tissues and a small amount of immature primitive neuroectodermal tissues in some areas. The omental nodules were all composed of mature neural glial tissues. Immunohistochemistry showed that the ovarian immature teratoma was positive for SOX2 and negative for OCT4, while the peritoneal glial nodules were positive for SOX2, GFAP, and S-100, and negative for OCT4. Conclusion OIT combined with GP is rare. Clinical treatment is based on the staging and grading of OIT, involving surgical resection and appropriate chemotherapy. The prognosis is usually good, but there is still a risk of recurrence and malignant transformation, requiring close follow-up.
Keywords：Immature teratomaPeritoneal glial tumor diseaseClinical pathologyImmunohistochemistry
Publication Date：2025-09-28
Online Publishing Date：2025-11-13(First online date of this platform, not the publication date of the document)
Pages：3( 1218-1220 )