Electrochemical detection of ciprofloxacin hydrochloride based on multiwall carbon nanotubes modified glassy carbon electrode
CONG Qiao
SONG Xiang-meng
QIN Hong-wei
ZHENG Xiao-lei
Abstract：The multiwalled carbon nanotubes modified glassy carbon electrode ( MWNTs/GCE ) was pre-pared by drop-coationg method with the MWNTs suspension,and the electrochemical behavior of ciprofloxacin hydrochloride ( CPLX) on the modified electrode was studied by linear sweep voltammetry ( LSV) ,then the opti-mal electrochemical detection conditions of CPLX were investigated. An irreversible oxidation peak of CPLX was observed on the MWNTs/GCE in Na2HPO4 ~NaH2PO4 ( pH=5. 5) buffer solution,and the peak current was proportional to CPLX concentration in the range of 2. 0 × 10 -6 to 5. 0 × 10 -5 mol/L,the regression equation with the correlation cofficient of 0 . 99363 was Ip ( μA ) =0 . 98806 × C ( μmol/L ) +13 . 76967 . The detection limit was 1. 0 × 10 -6 mol/L based on the observation of the oxidation peak as the standard. The relative standard devi-ation ( RSD) of successive determinations was less than 4. 56% ( n=10) . The average recoveries of the samples were 97. 4%,96. 99% and 107. 93%,respectively.
Keywords：multiwall carbon nanotubesmodified electrodeciprofloxacin hydrochlorideelectrochemical detection
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 54-60 )