The load of doxorubicin hydrochloride and folic onto/into yolk-shell structured aluminum phenylphosphonate microspheres
SHI Xin
ZHANG Fan
Abstract：The yolk-shell structure aluminum phenylphosphonate microspheres possess not only a special"core@void@shell"structure,but also two opposite properties in one particle,i. e. anionic core and cationic shell,which makes them adsorb anionic and cationic ions simultaneously. The yolk-shell structure aluminum phenylphosphonate microspheres were used as carriers,their load behavior for doxorubicin hydrochloride of anti-cancer drug and folic acid of targeting agent was investigated by using Ultraviolet-Visible spectrophotometry. The results indicate that aluminum phenylphosphonate microspheres can efficiently load anticancer drug of doxo-rubicin hydrochloride,and load enough folic acid to meet the requirement of targeting to cancer cells.
Keywords："Yolk - shell"structurealuminum phenylphosphonatedoxorubicin hydrochloridefolic aciddrug carriers
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 49-53 )