An algorithm for solving steady -state optimization problem of a class of biochemical systems
XU Gong-xian
LV Ying-hao
XING Yan-bing
YU Chao
Abstract：An iterative optimization algorithm that can rapidly solve the steady -state optimization problem of a class of biochemical systems is proposed according to a modified iterative IOM ( Indirect Optimization Meth-od, IOM) approach.This algorithm takes advantage of the modified iterative IOM approach that can be solved with available linear programming techniques .But no kinetic order parameters are required to be computed at each iteration of the proposed optimization algorithm .Numerical experiments show the tractability and effective-ness of the presented method .Compared with the original modified iterative IOM approach , the proposed algo-rithm has a low computational burden .
Keywords：biochemical systemssteady-state optimizationalgorithmlinear programming
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 97-103 )