1Development of endoscopic retrograde cholangiopancreatography in China: 50 years of endoscopic retrograde cholangiopancreatography in the worldWANG Peng, PAN Jun, HU Bing, LI Wen, GUO Xue-gang, JI Ming, MA Shu-ren, LI Zhao-shenACADEMICIAN FORUM677-6802Research progress of pulmonary function testing in 2017LIANG Xiao-lin, ZHENG Jin-pingCOMMENTARY681-6843Current status of intravenous thrombolysis for acute ischemic stroke in ChinaDONG Yi, DONG QiangSEMINAR685-6884Current situation and direction of green channel construction of intravenous thrombolysis in ChinaHUANG Qiang, HUANG Li, YANG Li-peng, WU JianSYMPOSIUM689-6925Risk evaluation and treatment of hemorrhagic transformation after intravenous thrombolysisYE Chen, WEI Chen-chen, LIU MingSYMPOSIUM693-6986Research progress in intravenous thrombolysis guided by multimode image evaluationZHANG Sheng, LOU MinSYMPOSIUM699-7037Collateral status in intravenous thrombolysis for acute ischemic strokeWANG Chao, JIN Hang, LUO Yun, YANG YiSYMPOSIUM704-7098Current situation and prospect of intravenous thrombolytic therapy for acute ischemic strokeYAO Zhi-guo, CHEN Hui-shengSYMPOSIUM710-7139Individualized decision-making in intravenous thrombolysis for acute ischemic strokeJIANG Nan, PENG BinSYMPOSIUM714-71810Current situation and prospect of intravenous thrombolytic therapy for acute ischemic strokeZHANG Pei-lanSYMPOSIUM719-72611Chinese expert consensus on diagnosis and treatment of multiple organ dysfunction syndrome induced by infection in the elderlyGUIDELINE AND CONSENSUS727-73812Interpretation of asthma guidelines in the 2018 global initiatine for asthma management and preventionZHANG Qing-lingGUIDELINE AND CONSENSUS739-74113Etiological analysis of 274 cases of esophageal ulcerFEI Gui-jun, WU Dong, WU Xi, YANG Ai-mingORIGINAL CONTRIBUTION742-74514Temporal distribution of epileptic seizures arising from different brain regionsYAN Jian-wei, JIN Bo, WANG Zhong-jin, MING Wen-jie, WANG Shuang, DING Mei-ping, GUO YiBRIEF REPORT746-74815Clinical analysis of six cases of autoimmune encephalitis associated with leucine-rich glioma inactivated 1 proteinWANG Ying, SONG FanBRIEF REPORT749-75216Analysis of the next generation sequencing results in 29 patients with acute lymphoblastic leukemiaLIANG Pei-qi, LIU Zhuo-gang, HU RongBRIEF REPORT752-75417Advances in research on taste dysfunction associated with Alzheimer's diseaseYAN Chao, WEI Yu-jia, DU Hong-zhen, XIE Ying, WANG Long, LI Zeng-ningREVIEW755-75818Research status of obstructive sleep apnea syndrome complicated with depressive stateLIANG Yan, WANG WeiREVIEW759-76119Research progress in systemic lupus erythematosus with heart failureREN Hao, XU Ding-liREVIEW762-76520Research progress in gut microflora and cardiovascular diseasesCHEN Xiao-qing, WANG Nan, JING Zhi-cheng, GUANG Xue-feng, DAI Hai-longREVIEW766-769 