1Analysis on the patent of rare diseases in China:based on a two-mode network perspectiveLI Shu-xiang, CHU Shu-zhen, YANG Qing617-6232Prediction of the varieties into drug patent time extended under the background of new patent law in ChinaWANG Yu, GU Dong-lei, CAO Xiao-die, JIAN Yu-cong, PAN Xiao-mei624-6283Long-term efficacy evaluation of anti-cancer immunotherapyLI Ruo-bing, PAN Jian-hong, HE Juan, YAN Fang-rong629-6344Clinical trial design of traditional Chinese medicine from the perspective of scientific examinationHAN Fang, LIU Bao-li, CHENG Jin-lian, LIU Qing-quan635-6385Application of target-organ toxic dose modification of HI method in the assessment of combined exposure to lead, cadmium and arsenic in Polygonatum odoratum ( MilL) DruceZUO Tian-tian, FANG Cui-fen, JIN Hong-yu, WANG Dan-dan, GAO Fei, LI Li, MA Shuang-cheng639-6446Research progress on quality evaluation methods of chewable tabletsZHU Chun-mei, TENG Jian-hao, ZHANG Meng, WU Hao-xiang645-6547Research progress of the new triple antibacterial drug Recarbrio in the treatment of complicated intra-abdominal infectionsZHANG Meng, ZHU Chun-mei, TENG Jian-hao, WU Hao-xiang, ZHANG Fu-li655-6638Bioequivalence of domestic recombinant human growth hormone injections in healthy Chinese volunteersLIU You-ran, WANG Bian-zhen, DONG Li-hou, CHEN Dong-lin, LU Chun-yan, JIN Ji-ting, WANG Li, SUN Xiang-yu, SONG Hai-feng, ZHENG Li664-6689Qualitative study on the experience of healthy subjects participating the phase Ⅰ drug clinical trialsCHEN Jun-yi, WU Jun-yan, CHEN Jie, YE Sui-wen, MAI Qing-xiu, CHEN Shu-ping669-67410Discussions on key points of phase Ⅰ clinical trial of injectionDU Dan, LI Feng-shan, YU Qin675-67811Apigenin-piperazine co-crystal: preparation, characterization and in vitro anti-tumor efficacySHENG Li-song, REN Li-wen, YANG Shi-ying, WANG Jin-hua, LV Yang, DU Guan-hua679-68412Quality standard study of Xiao'er Zhixiao Pingchuan GranulesWANG Di-lei, ZHONG Lin-ying, BAI Jie, ZHANG Yi, FAN Xiao-yu, PENG Jing, PENG Zheng-ping, DU Shou-ying685-69213Effect and mechanism of Arenaria kansuensis Maxim. Extracts on the Proliferation and Apoptosis of Human Hepatocellular Carcinoma HepG2 CellsLEI Ning, XU Ben-shan, LV Ya-li693-69814Stability study on reference standard of impurity B in ambroxol hydrochloride in different solventsZHANG Ya-jun, CHEN Zhong-lan, SUN Hui-min, WANG Qing, WU Xian-fu699-70415Establishment of HPLC fingerprint and determination of multiple components in Eucommiae Cortex formula granulesLI Ze-na, LIU Chang, LI Xue, CHEN Hong-ping, HU Yuan, LIU You-ping705-71216Comparison of the efficacy and safety between ceftazidime/avibactam and carbapenemsGUO Xiao-long, CUI Xiang-li, LI Ji-yang713-720 