1Primary immunodeficiency:Starting from digestive system diseaseHU JianEDITORIAL481-484,5022Primary immunodeficiency disease and inflammatory bowel disease in childrenLIN Yi, ZHANG Qiu-yeA CENTURY OF COMMITMENT TO PEOPLE'S HEALTH BY THE COMMUNIST PARTY OF CHINA485-4903Problems of liver and spleen related to inborn error of im-munityYANG Xi, TANG Xue-meiA CENTURY OF COMMITMENT TO PEOPLE'S HEALTH BY THE COMMUNIST PARTY OF CHINA490-4934Primary immunodeficiency with malformation of gastro-intestinal structureGU Yu, SUN Jin-qiaoA CENTURY OF COMMITMENT TO PEOPLE'S HEALTH BY THE COMMUNIST PARTY OF CHINA494-4975Chronic diarrhea and primary immunodeficiencyHE Ting-yan, YANG JunA CENTURY OF COMMITMENT TO PEOPLE'S HEALTH BY THE COMMUNIST PARTY OF CHINA497-5026Expression and significance of serum high mobility group protein box 1 in Henoch-Sch?nlein purpura patientsRUAN Xiao-xia, LUO Chong, AN Yun-feiORIGINAL CONTRIBUTION503-5077Clinical features and electroencephalographic characteristics of focal inhibitory motor seizureWANG Shi-yu, ZHAO Xuan, LI TingORIGINAL CONTRIBUTION508-5138Relationship of folate and vitamin B12 with symptoms and mental development of children with autism spec-trum disorderCAI Xiao-fan, GUO Min, LIU Li-yanORIGINAL CONTRIBUTION514-5179Clinical analysis of 21 cases of pancreaticobiliary malformation complicated with children's pancreatitisJIA Qian-ru, GUO Jing, SUN MeiORIGINAL CONTRIBUTION518-52210Clinical features of hereditary spastic paraplegia type 31 and analysis of REEP1 gene mutationHU Qing-qing, SU Tang-feng, XU San-qingORIGINAL CONTRIBUTION523-52611Clinical manifestations of 4 cases of Lesch-Nyhan syndrome with onset at infancy and analysis of HPRT1 gene mutation and the literature reviewWANG Jun, HAN Lin, WANG YanORIGINAL CONTRIBUTION527-53212Longitudinal study of infant sleep problems and their influencing factorsZHOU Zi-qi, LI Zheng, YE YaORIGINAL CONTRIBUTION533-537 