1Animal models and experimental medicine and the Nobel Prize in Physiology or Medicine 2021— TRPV and PIEZO receptors for temperature and touch sensationYu Zhang, Dongyuan Zhang, Chuan Qin296-2992Hypoxia adaptation in the cornea: Current animal models and underlying mechanismsKunpeng Pang, Anton Lennikov, Menglu Yang300-3103Adaptation of mammals to hypoxiaFang Li, Zhenglei Qiao, Qijiao Duan, Eviatar Nevo311-3184The hypoxia adaptation of small mammals to plateau and underground burrow conditionsMengke Li, Dan Pan, Hong Sun, Lei Zhang, Han Cheng, Tian Shao, Zhenlong Wang319-3285Folic acid- induced animal model of kidney diseaseLiang-Jun Yan329-3426A novel mind- set in primate experimentation: Implications for primate welfareAntonella Tramacere, Atsushi Iriki343-3507Establishment of an oligoasthenospermia mouse model based on TAp73 gene suppressionHong-Juan Liu, Meng-Yun Deng, Yan-Yan Zhu, De-Ling Wu, Xiao-Hui Tong, Li Li, Lei Wang, Fei Xu, Tong-Sheng Wang351-3588Development of a unilateral ureteral obstruction model in cynomolgus monkeysLinghong Huang, Jia Ni, Tanika Duncan, Zhizhan Song, Timothy S.Johnson359-3689Implication of proliferation gene biomarkers in pulmonary hypertensionYi Yan, Rong Jiang, Ping Yuan, Li Wen, Xiao-Bin Pang, Zhi-Cheng Jing, Yang-Yang He, Zhi-Yan Han369-38010Novel rat model of multiple mitochondrial dysfunction syndromes (MMDS) complicated with cardiomyopathyYahao Ling, Jiaxin Ma, Xiaolong Qi, Xu Zhang, Qi Kong, Feifei Guan, Wei Dong, Wei Chen, Shan Gao, Xiang Gao, Shuo Pan, Yuanwu Ma, Dan Lu, Lianfeng Zhang381-39011Closed cranial window rodent model for investigating hemodynamic response to elevated intracranial pressureMatt T.Oberdier, James F.Antaki, Alexander Kharlamov, Stephen C.Jones391-39712Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial modelAhmet Kinaci, Wilhelmina Bergmann, Sander van Thoor, Saskia Redegeld, Albert van der Zwan, Tristan P.C.van Doormaal398-40513In- depth examination of hyperproliferative healing in two breeds of Sus scrofa domesticus commonly used for researchColton H.Funkhouser, Liam D.Kirkpatrick, Robert D.Smith, Lauren T.Moffatt, Jeffrey W.Shupp, Bonnie C.Carney406-41714Heterozygous lipoprotein lipase knockout mice exhibit impaired hematopoietic stem/progenitor cell compartmentGuiying Shi, Xinyue Li, Keya Li, Yiying Huang, Xuepei Lei, Lin Bai, Chuan Qin418-425