1Examining the role of real-world study from the whole life cycle of Chinese medicineLU Yao, WANG Hai-nan2225-22272Analysis of current research situation of anti-tumor traditional Chinese medicine from the perspective of patentsZANG Mei-tong, ZHANG Jing, YANG Yin-li, ZHANG Jie2228-22333Reflections on patent management under the situation of accelerated approval of new drugs based on an analysis of the research and development process of osimertinibYANG Qian, JIN Chun-peng, ZHENG Ru, MA Qiu-juan2234-22414Study on ability evaluation model for drug review authorityLI Feng2242-22485Novel designs for early clinical trials of anticancer drugsLI Ruo-bing, HE Juan, YAN Fang-rong, PAN Jian-hong2249-22556Comparative study of two in vitro experimental methods detecting cytokine release syndromeXU Jing-yi, YU Jia-yi, MA Jing2256-22617Discussion on research ideas of post-marketing clinical re-evaluation of traditional Chinese medicineCHEN Yu-huan, LING Xiao, LI Chun-xiao, WANG Pan-pan, LIU Shu-yu, MA Zhi-huan, LI Xue-lin2262-22678Mitochondrial dysfunction in non-alcoholic fatty liver disease and its therapeutic strategiesLEI Lei, PENG Zong-gen2268-22759The evaluation method and implementation points of bioequivalence study of transdermal patchesSUN Hua, LIANG Da-hu, LI Xiang-hong, HU Hua, XU Mao-di, GUO Yi-yun, XIE Hai-tang2276-228210Effect of butylphthalide on hsCRP and TNF-α in patients with anterior choroidal artery infarction with broadened therapeutic time windowWANG Jia-jun, GAO Ju, ZHOU Gang, XIAO Zhan-chi2283-228711Thoughts and recommendations arising from a review of"subcenter contracts"for clinical research initiated by investigatorsCAO Ye, QIN Li-ying, JIANG Hui, CHEN Shuang-zhen, LI Can, LIN Ting, ZHANG Jing-min, WANG Pan2288-229412Discussion of standardized assessment and emergency treatment for hypersensitivity reactions in early clinical trials of anti-tumor monoclonal antibody drugsFANG Ying-ying, LIU Long, LI Yin-juan, WANG Xing-he2295-229913Preliminarily explore the effect of panax notoginseng saponins on differentiation of mouse treg cells and its mechanismWANG Xiang, DI Yu-xi, SHEN Mei-yu, ZHANG Ming-fei, XU A-lan, ZHOU Ling-ling2300-230514Research on the development of methods in CAR-T cell therapy and its quantitative reference using digital PCRDOU Min-hua, ZHU Bing-mei, ZONG Wei-ying, WU Xiao-shuang, YANG Zhi-xing2306-231415Methodology validation of the determination of aerodynamic particle size distribution by next generate impactorLI Xuan-tang, CHEN Cui-cui, WEI Ning-yi, ZHOU Ying, NING Bao-ming2315-232116Retrospective analysis of 241 cases of severe cutaneous adverse reactions caused by antibioticsCAO Ming-xue, HUANG Ya-qun, ZHANG Jiao, YU Zhi-ying, WEN Rui-ting, FENG Yu-fei2322-2327 