1Evaluation on the strategy layout of nilotinib patentsYANG Lei, DONG Li1489-14942Analysis the patent layout strategy of foreign pharmaceutical companies in the field of chimeric antigen receptor T cell therapy:taking Kite Pharma company as an exampleZHANG Zhi-xian, SUN Shang-yu1495-15023Analysis of the current situation and development trend of mergers and acquisitions in China's pharmaceutical industry in the past 10 yearsFANG Zhong-jian, WANG Cai-yi, SHEN Chen, FAN Yu-lu, CHEN Li-ping, WANG Yi, SHAO Rong, SHAO Ming-li1503-15064Analysis on the innovation performance and its influencing factors of biomedical industrial parks in Jiangsu provinceZHANG Yan-jun, LI Xin, JIANG Sheng-qiang1507-15135Knowledge map study of drug regulatory science research in China:based on journal literature of CNKIMIN Xiao-qi, YUAN Xiao-liang, YAN Wei-jiang1514-15226Analysis and thinking on the application and approval of improved new chemical drugs in ChinaLü Yi, ZHANG Yi-meng, MAO Ning-ying1523-15307Tumor diagnosis and treatment strategies based on targeting folate receptorHE Wen-li, DONG Xing, YAN Meng, XU Jia-qi, XIANG Bai, YANG Shao-kun, CAO De-ying1531-15378Therapeutic targets of cough and research progress of new antitussive drugsYAO Yue, WU Hao, ZHANG Jia-shuo, SU Wei-wei, LI Pei-bo1538-15459Clinical efficacy and safety of apatinib in advanced gastric cancer with different blood supplyCHEN Qi, HU Chang-lu, WEI Xin, WANG Dan, LIU Jia-jia, ZHU Qi-zhi, XU Wei-ping1546-155110Study on linaclotide in the treatment of IBS with predominant constipation: a prospective cohortYIN Hua, ZHAN Yu, WEN Xu-dong, WANG Xiao-xiang, WEN Yong1552-156011Mechanism on persimmon leaf extract in the treatment of ulcerative colitis through TLR4/NLRP3 inflammatory signal pathway and intestinal floraZHANG Xue-xia, LIU Fang-zhou, LIANG Rui-feng, ZHOU Min, LIU Chang-he, LI Hua-ni, GUO Xiao-yan1561-156912Effects of different drying methods on chemical composition and powder properties of Xiaochengqi Decoction dry extract powderGUO Wen-hui, SHAN Jia-ming, ZHU Wen-jie, YANG Wu-liang1570-157713Preparation of iridin and its regulatory effect on isolated mouse intestinal smooth muscleXIONG Hao, GAO Meng, YANG Yuan-feng, GUO Wen-hui, SHAN Jia-ming, ZHU Wen-jie, YANG Wu-liang1578-158414Literature review and analysis of adverse drug reactions of brentuximab vedotinLü Man, CHEN Jing, CHEN Zhe1585-1592 