1Countermeasures for registration application of drug manufacturing enterprise after the official implementation of eCTD in ChinaCHEN Hua, XING Hua1177-11842Optimization of new drug R&D strategy in pharmaceutical enterprisesZHAO Mu-zi, HUANG Zhe1185-11903Evolutionary game simulation of tripartite strategy of delegated manufacturing of traditional Chinese medicine preparations in medical institution under MAH systemYAN Yu, WEI Hua, TAO Qun-shan1191-12004Research on core assessment indicators for human use experience of traditional Chinese medicine based on Delphi methodZHI Kai, SU Peng-li, LIU Jun, YU Ya-nan, LI Bing, XU Hai-yu, LI Geng, SHEN Chun-di, LIAO Xing, DANG Hai-xia1201-12055Analysis and countermeasures of main problems in pre-approval inspections of innovative chemical drugsYE Xiao, DONG Jiang-ping1206-12116Progress in research on chemical constituents and pharmacological mechanism of Bletilla striata extract in tissue repair and reconstructionZHANG Qian, XU Qiang, LIANG Zheng, ZHANG Zhao-hui1212-12197Research progress of calcium nanoparticles in tumor immunotherapyZHI Wei-wei, ZHU Xia-li, JIA Yong-yan, XU Zhi-ling, LI Yi-jing, HUANG Sheng-nan1220-12278Mechanisms and strategies of endocrine therapy resistance in breast cancerXU-YANG An-tai, WANG Mei-chen, MIAO Jin-qian, YANG Feng-hua, YU Ting-yao, ZHOU Yi-ping1228-12329Advances in research on the safety of secukinumab in terms of tuberculosis infection in the treatment of spinal arthritis-related diseasesSONG Xiao-yan, LIU Chun-hong1233-123610The effects of remimazolam in total intravenous anesthesia patients undergoing radical thyroidectomyYI Wan-qing, HU Qi-yun, QIAN Shao-jie, LIU Jin-tao, MAO Hui, CAI Fang, WANG Wen-yuan1237-124211Prediction of potential quality markers of Aurantii fructus immaturus based on chemical pattern recognition and network pharmacologyLI Can, ZENG Juan, LONG Yu-qing, ZENG Mei, ZHOU Xin-ru, YANG Min, ZHOU Yi-yun, ZHOU Ri-bao, LIU Xiang-dan1243-125212Effects of high-altitude hypoxia environment on pharmacokinetics of metformin after multiple administration in type 2 diabetes mellitus ratsLUO Lin, HUANG Dong, ZHANG Xiao-jing, LI Wen-bin, WANG Rong1253-125813Study on differential components of Ge-Gen Decoction compound granules,kampo granules and Ge-Gen Decoction formula granules based on UHPLC-Q-TOF-MSZHANG Jin-ying, ZHOU Ning, LIU Tong, WANG Yong-xiang, CAO Yu-min, LIU Zhen-hui, ZHENG Xiao-ke, FENG Wei-sheng1259-126814A case of anti-SOX1 paraneoplastic neurological encephalitis induced by atezolizumab in patient with small cell lung cancer and literature review of neurological adverse eventsLI Xiao, ZHANG Yan-hua1269-127415Risperidone-associated venous thromboembolism in the treatment of schizophrenia:a case report and literature reviewWU Sheng-jie, JIANG Xiao-jin, JING Li1275-1280 