1Global approved new drugs in 2021: retrospect and prospectDU Yi-hang, SUN You-song, CHEN Qian, YANG Zhen-zheng, ZHENG Xiao-nan1033-10412Incentive policies for pediatric drug developmentGONG Chuan-huan, YANG Yue, TIAN Li-juan1042-10473A new drug in the treatment of gastrointestinal stromal tumor:tyrosine kinase inhibitor avapritinibLI Hong-dou, WANG Long1048-10514General considerations on the risk assessment of adventitious agents of advanced therapeutic productsXU Long-chang, CUI Jing, WEI Wei1052-10565The antihypertensive effect of compound reserpine and triamterene tablets on the regulation of intestinal flora in ratJIANG Yu, LIU Shan, YUAN Tian-yi, ZHANG Wen, LI Li, WANG Shou-bao, FANG Lian-hua, DU Guan-hua1057-10656Research progress of in vitro permeability research of generic drugsLIU Xue-jing, LI Wen-long, GUAN Hao-yue, XU Ming-di1066-10717Research progress of antitumor small molecule modulators targeting SOS1FAN Yi-qing, TANG Chun-lei, FAN Wei-zheng1072-10798Retrospective comparison of efficacy and adverse reactions of rituximab and its biosimilar in CHOP chemotherapyHE Xin, ZHUANG Li-ping, LI Qi-zha, HUANG Hong-bing, LIU Tao, ZHOU Jie1080-10849Practice path and management strategy on accelerating ethical review efficiency in one infectious disease hospitalZHOU Yun-ao, WAN Gang, YANG Zhi-yun, JIA Wang-yan1085-109010Construction of the evaluation index system for the comprehensive ability of medical ethics committeeWU Jue, DU Xu, LIU Jing, JIANG Hui, TANG Hong-chuan, SUN Yun1091-109511Antibacterial effect and composition analysis of the leaves and spicas from Schizonepeta tenuifolia BriqSU Chang, ZHAO Yan-yun, FENG Yuan, ZHANG Lan-lan, ZHENG Yu-guang, ZHENG Kai-yan1103-111112Development and application of the determination methods for total sugars, total saponins and total lignans in Shengmai InjectionLIU Rui, NIE Li-xing, CHEN Jia, DAI Zhong, WANG Gang-li, MA Shuang-cheng1112-111813Differences of glycosylation at N538 site of targeted PD-L1/TGF-βbispecific antibodyLI Ke, YU Fei, SHEN Zhen-duo, HUO Li-nan, CUI Yuan-yuan, LIU Wan-hui1119-112414Data mining and analysis of security alert signals of tofacitinibHAN Qiang, PAN Chen, ZHENG Ming-wei, SUN Yi-qi, YIN Hang, DONG Rui-hua, SHEN Su1125-113115Donepezil associated sinus bradycardia in the treatment of Alzheimer's disease and literature reviewWU Sheng-jie, ZHU Yu-bing, JING Li1132-1136