1Advance in clinical research of febuxostat in the treatment of goutLIU Yu-yan, LI Yue-dong, TANG Jian-fei, SHEN Ru-jie, YAO Cheng-e1103-1106,11142Improving Chinese innovation system of new drug according to 30-year history of U.S.Orphan Drug ActYI Ba-xian, WANG Guang-ping, JI Hai-hong, WU Xiao-ming1107-11143Influencing factors and the solutions for the determination of related substances by HPLC in drug research and developmentYANG Fang1115-1117,11324Main problems and analysis of modification of registration specifications in the supplementary applicationTIAN Jie, ZHANG Zhe-feng1118-1120,11265Advances in strategies and clinical applications of interleukin-1 antagonistsYU Chen-lin, ZONG Ying, ZHANG Xiao-fang, YUAN Bo-jun, CUI Shu-fang, LU Guo-cai1121-11266Uncertainty evaluation in determination of methylergometrine in human plasma by HPLC-MS/MSQI Hui-hong, LI Yang, SHI Ai-xin, HU Xin, BI Kai-shun, WANG Tie-jie1127-11327Preparation of antisera against serotype 23F Streptococcus Pneumoniae and their specificity in immunological methods1133-1138,11458Research advances in the pathogenesis of diabetic nephropathy and the development of anti-diabetic nephropathy agentsL(U) Meng, HU Gao-yun, TU Zhi-jun, YU Zu-tao, ZHOU Kun, LI Qian-bin1139-11459Advance in studies on pharmacological effect and clinical application of microecologics in treating constipationLI Hui-fen1146-1148,116210Recent advances in determination methods of drug protein bindingGUAN Jin, DING Shuang, LIU Zhi-han, DONG Xi-xin, YAN Feng, SHI Shuang1149-115311Influence of various genotypic combinations of CYP2C9 and VKORC1-1639G ＞A on mean daily dose of warfarin: a Meta-analysisLEI Zhao-jin, ZHANG Rui-lin, LI Zhong-dong1154-116212Effects of compound fluid of Cortex Phellodendri on inflammatory cytokines and growth factors in external treatment of diabetic foot ulcerLI You-shan, YANG Bo-hua1163-116613Effect of dexmedetomidine on the hemodynamics and effect-site concentration of etomidate given by target-controlled infusionMIAO Zhuang, PAN Ming, HUANG Lin, WEN Qing-ping1167-1170,117414Comparison of sufentanil and dezocine anesthetic effects on trigeminal neuralgia undergoing radiofrequency thermocoagulation1171-117415Quickly discovering novel antitubercular compounds based on Mycobacterium smegmatis modelGUAN Yan, YANG Yan-hui, ZHOU Shuang, HE Qi-yang, MENG Jian-zhou, SI Shu-yi, XIAO Chun-ling1175-1179,118716Antidepressant effect of licorice flavonoids from Glycyrrhiza uralensis on stress-induced depression and the key protein SYP/PSD95 associated with synaptic plasticity in rats1180-118717Protective effect of F1013 on ConA-induced acute hepatic injury in miceDENG Li-juan, LI Zhan-jun, LUO Ying, FAN Hui-hong1188-1191,119618Protective effect of insulin on neuronal injury induced by Aβ25～35SHI Jing-yu, CHEN Si, SUN Yan, CUI Hong-wei, TIAN Tian, ZHANG Bo-ai1192-119619Graphical synthetic routes of linagliptinSUN Cheng-yu, WU Chun-jiang, ZHU Wu-fu1197-120020New synthetic process of mitiglinide calciumWANG Jiang-xia, WANG Pan, QI Shan, LIU Li-yun, SHANG Zhen-hua1201-1203,1209 