1HIM is the inevitable and necessary direction for the future development of medicineFAN Dai-MingCelebrity Forum1-102An inevitable trend of holistic integrative medicine in integrated traditional Chinese and western medicine: a discussion from research dilemma of rheumatoid arthritisZHANG Di-Sheng, WANG Ji-ZhongExpert Review11-143Reversal of brain death: the prosperity of medicine or the medical challenge to philosophy?TANG Xu, GOU Xing-Chun, XU Li-Xian, MEI Xiao-PengExpert Review15-18,234Cancer cells have independent lifeSUN Cheng-DongSpecialist Forum19-235Understanding the cosistency of metabolism and immunity based on their treatments of exogenous substancesYUN Yu, WANG Lei, DUAN Wei-GangSpecialist Forum24-276Vascular endothelial dysfunction may be a common initial factor of development of vascular calcification and osteoporosisZHAO Li, LIU Wen-Li, LIU Yan, ZHAO Yu-XiaHypothesis28-307Heart is no longer the center of blood circulation?——Consultation with Professor Jiang Hongyan for “heart-heart” or “lung-heart”GUO Wen-JieAcademic Debate31-348Pi in traditional Chinese medicine refers to pancreas rather than spleenCHEN Yong, CAI Jian-Fei, ZOU Jun, LUO Dan, GUAN Jian-LongAcademic Debate35-389Can vitamin really be used in these ways?LUO Hao-XiangAcademic Debate39-4210Several practical problems in the book named Traumatic Orthopedics TutorialXU Ming-Xi, SHENG Lei, ZHAO Jun-Hua, WANG Li-JunAcademic Debate43-4511Doubting the indications of lateral line 1 and lateral line 2 of vertex in Acupuncture textbook and national scalp-acupuncture standardTIAN Kai-YuAcademic Debate46-48,5212Does lidocaine prolong effective refractory period of myocardium relatively?DING Shao-Xiang, ZHANG Hong-Kao, WANG Zhi-JieAcademic Discussion49-5213Definition of the glioma resection border: a difficult challenge for neurosurgeonsZOU Xi-Feng, CHENG Guang, WANG Jiang, GAO Hai-Feng, YIN Hua-Long, FEI ZhouAcademic Discussion53-5514Understanding of diagnosis of acute kidney injury associated with severe acute pancreatitisBI Li-Ming, LI Hong-Chang, CHEN Ya-Feng, FENG Dian-XuAcademic Discussion56-6115Paroxysmal kinesigenic dyskinesia presenting with transient involuntary twitching movements involving right leg in a 24-year-old man responding well to topiramateYU Yong-Peng, SUN Ren-Tao, REN Wei-Feng, TAN LanAcademic Discussion62-6416Ethical debate of “three-parent technique” and exploration of countermeasuresFENG Xin-Wei, YANG Xiao-Li, YANG Mi, CHEN Ye-Wei, LI Li-HongEthics65-6817Ethical risks of wholly foreign-owned hospitals and avoidance strategyLIU Sheng-LiangEthics69-72,7518Informed consent: the more is the better for patients?LI Hua-Wei, WANG Xu-FangViewpoint and Perspective73-7519Is it reasonable to work in spite of illness?GUO Zui-Yuan, LI Dong-LiViewpoint and Perspective76-78 