长链非编码 RNA 在骨关节炎与骨肿瘤领域的研究进展
孙红
张志奇
傅明
1.中山大学附属第一医院关节外科, 广州,5100802.中山大学附属第一医院关节外科, 广州,5100803.中山大学附属第一医院关节外科, 广州,510080
摘要：Long noncoding RNAs ( lncRNAs ) are the vast majority of noncoding RNAs in mammalian genome. Long noncoding RNAs are involved in gene expression via chromatin remodeling, transcriptional and post transcriptional regulation. Recently, aggregated studies indicate that plenty of lncRNAs in bone and joint disease are differently expressed and deeply involved in many pathological changes. In this review, we focus on the molecular mechanisms of lncRNAs and the role of lncRNAs in the pathogenesis of bone and & joint disease.
关键词：RNA RNA骨关节炎骨肿瘤基因表达调控关节炎类风湿骨质疏松长链非编码 RNA
分类号：R738.1(运动系肿瘤)R681.3(骨科学（运动系疾病、矫形外科学）)
资助基金：国家自然科学基金(81572171)
论文发表日期：2016-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 397-400 )
英文信息