脊柱多发硬化性上皮样纤维肉瘤一例报告
宇尧1
刁小莉2
杜心如1
骆辉1
徐子1
1.首都医科大学附属北京朝阳医院骨科, 北京,1000202.首都医科大学附属北京朝阳医院病理科, 北京,100020
摘要：Objective To study pathological features, diagnosis and differential diagnosis, and treatment of sclerosing epithelioid fibrosarcoma ( SEF ). Methods Clinical manifestations, pathological morphology, immunohistochemical staining, and treatment of cervicothoracic vertebrae SEF in 1 patient were analyzed with related literature review. Results The case ( male, 62-year-old ) of cervicothoracic vertebrae SEF was first reported. Primary tumors located in cervical vertebrae and thoracic vertebrae, inducing spinal cord compression. A large amount of irregular cord-like trabecular collagen was found in tumors. Rarefaction of tumor cells and spindle cells around the collagen was observed, among which were epithelial cells. Calcification and ossification were found in certain areas of the tumor. Immunohistochemical staining showed that the tumors were positive in Vimentin ( 3+ ), CD99 ( 3+ ), Bcl-2 ( 2+ ), KI-67-LI ( 15%+ ), while negative in SMA, Desmin, NF, CgA, S-100, HMB-45, CD34, EMA, CK8, CK19, CK7, p53, CK, CK5, GFAP, CD68, CD21, CD163, CD1a and S-100. Conclusions SEF is an extremely rare type of fibrosarcoma. It can be confirmed by pathological examination and immunohistochemical study. Surgical treatment is the main option.
关键词：脊柱纤维肉瘤诊断鉴别骨肿瘤外科手术
分类号：R738.1(运动系肿瘤)
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 989-992 )
英文信息