Study on anti-allergy efficacy of Nepeta cataria prescriptions
REN Han-kun
LIU Yu-hong
MENG Hong
DONG Yin-mao
Abstract：Nepeta cataria prescriptions were extracted with distilled water and the mass concentration of Nepeta cataria in the extract was 0.05 g/mL.The animal models of anti-pruritus,passive cutaneous anaphylaxis (PCA)and dehydrated skin of guinea pig after allergy were applied to study relieve itching,detumescence and allergic skin repair activity of the active extraction.Results showed that the extracts of Nepeta cataria prescrip-tions with mass concentration of 0.5 wt% could significantly mitigated the amount of the histamine phosphate and run up the threshold of itch at (1 54 ±31 )μg.Further,vascular permeability by 1 5.5% with mass con-centration of 2.0 wt% and the protection rate of water dispersion in allergic skin was 1 8% with mass concen-tration of 0.5 wt%.Meanwhile,the extract of Nepeta cataria prescriptions in cream matrix also could promote relieve itching,eliminate the redness of red and moisturize the allergic skin in clinical evaluation.
Keywords：Nepeta catariaprescriptionsanti-aller-gy efficacymice level
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 44-48 )