Design of circular logic gate based on DNA strand displacement reaction
CUI Guang-zhao
WANG Xi
ZHANG Jun-ya
ZHANG Xun-cai
WANG Zi-cheng
WANG Yan-feng
Abstract：Using the DNA strand displacement technology that the reaction progress was programmable and the DNA strand dynamics was predictable,two logic computational models (logic NAND gate and NOR gate)with circular DNA as a basic work unit were designed based on DNA strand displacement reaction.In these mod-els,single-stranded DNA was regarded as the system input.Using many DNA recognition domains and toehold domains which were contained in circular DNA molecule,the output signal was accurately identified by detec-ting specific fluorescent signal to ensure the correctness and extensive applicability of these DNA logic gate models.
Keywords：DNA strand displace-ment reactioncircular DNAlogic gate
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 55-60 )