Research advance in cembranoid compounds

JIA Chun-xiao; HE Feng; MA Yu-ping; CHEN Zhi-fei; MAO Duo-bin

doi:10.3969/j.issn.2096-1553.2016.1.009

Abstract：The research progresses on cembranoids,such as separation,identification,qualitative and quanti-tative analysis,bio-synthesis and bio-degradation as well as chemical synthesis,have been reviewed.Based on the current available separation and analysis methods as well as studies on the formation and degradation of cembranoids in tobacco,column chromatography and HPLC methods have shown good performance on separa-ting and analyzing cembranoids both qualitatively and quantitatively whereas the procedures based on GC and GC-MS methods showed a relatively lower sensitivity to this kind of semi-volatile chemicals.The formation and degradation of cembranoids in tobacco were generally considered to be related to illumination,oxidation and biocatalysis.Many research works done on this aspect,however,no final conclusion has been made.Future research is expected to focus on the following directions:development of more straightforward,accurate and faster analysis methods;in-depth methodological research on biological degradation of cembranoids in tobacco to flavor components;mechanism studies on the formation and degradation of cembranoids.