Controllable 4-arm DNA tile self-assembly based on DNA strand displacement and sub-tile
YAO Li-na
ZHAO Tao-tao
LI Meng-meng
CUI Guang-zhao
WANG Yan-feng
Abstract:A controllable 4-arm DNA tile self-assembly based on DNA sub-tile and DNA strand displace-ment (DSD)was proposed based on original sub-tile.The impacts on time responses of this design was studied by designating new reaction rates to toeholds.Visual DSD results showed that increasing the popula-tion ratio-active strands to arm strands and assigning higher reaction rates of toeholds could accelerate DNA tile self-assembly.These simulation results could convince the possibility of implementing controllable DNA tile self-assembly at room temperature in laboratory.
Keywords:DNA sub-tile4-arm DNA tilecontrollable DNA tile self-assemblyself-assembly at room tem-perature
Publication Date:2014-11-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:6( 86-91 )