The Evaluation Value of Preoperative Coronary Artery Functional Indicators for the Improvement of Coronary Artery Blood Flow after PCI
FANG Lina
YAN Rui
CHEN Xiaozhen
YU Yunfu
YAN Jifeng
Abstract：Objective: To explore the value of preoperative coronary functional indices in evaluating coronary blood flow improvement after percutaneous coronary intervention (PCI). Methods: A total of 214 patients with acute myocardial infarction who underwent PCI at our hospital between January 2022 and May 2023 were selected as the study subjects. Before stent placement, coronary functional indices including fractional flow reserve (FFR), index of microcirculatory resistance (IMR), and coronary flow reserve (CFR) were measured. According to the thrombolysis in myocardial infarction (TIMI) classification after surgery, the patients were divided into no-reflow group (42 cases) and normal blood flow group (172 cases). The differences in clinical data and coronary functional indices between the two groups were compared, and the influencing factors of no-reflow and the predictive value of different indicators for no-reflow were analyzed. Results: The preoperative FFR and CFR levels in the no-reflow group were lower than those in the normal blood flow group, while age, total stent length, preoperative IMR, and D-dimer (D-D) levels were higher in the no-reflow group (P < 0.05). Logistic regression analysis showed that increased FFR was a protective factor for no-reflow, while increased IMR, total stent length, and D-D were risk factors for no-reflow (P < 0.05). Receiver operating characteristic (ROC) curve analysis showed that FFR, IMR, total stent length, and D-D had predictive value for no-reflow. Using the logistic regression equation of FFR, IMR, total stent length, and D-D as a combined indicator, the area under the curve (AUC) for predicting no-reflow was 0.940 [95% CI (0.908, 0.974)], with a sensitivity and specificity of 87.21% and 83.33%, respectively. Conclusion: Preoperative coronary functional indices FFR and IMR are influencing factors for no-reflow in patients with acute myocardial infarction after PCI. The combination of FFR, IMR, total stent length, and D-D has good predictive performance for no-reflow.
Keywords：no-reflowpercutaneous coronary interventionfractional flow reserveindex of microcirculatory resistance
Publication Date：2026-01-10
Online Publishing Date：2026-01-16(First online date of this platform, not the publication date of the document)
Pages：4( 102-105 )