The Influence of Wenyang Huoxue Formula Combined with Routine Cardiac Rehabilitation on Cardiopulmonary Exercise and Quality of Life in Patients with Stable Coronary Heart Disease after PCI Stent Implantation
NI Haoxuan
QIN Yueqin
ZHANG Li
CAO Lihua
LU Yingyi
HU Xiaozhen
CHEN Zhaoshan
Abstract：Objective: To explore the effect of Wenyang Huoxue Formula combined with conventional cardiac rehabilitation on pulmonary and cardiac function and quality of life in patients with stable coronary heart disease after percutaneous coronary intervention (PCI) stent implantation. Methods: A total of 73 patients with stable angina pectoris (Yang deficiency and blood stasis syndrome) classified as grade I or II according to the Canadian Cardiovascular Society classification were selected from the Department of Cardiology, Shanghai Traditional Chinese Medicine Hospital, from June 2022 to September 2023. All patients underwent PCI stent implantation and received conventional Western medical treatment. They were randomly divided into a control group (34 cases) and an intervention group (39 cases). The intervention group received Wenyang Huoxue Formula combined with conventional cardiac rehabilitation, while the control group received a placebo combined with conventional cardiac rehabilitation. The effects of different therapies on pulmonary and cardiac function and quality of life in patients with stable coronary heart disease after PCI stent implantation were compared. Results: After treatment, peak VO2, VO2max, VCO2max, VEmax, and METsmax in both groups showed statistically significant differences compared to pre-treatment (P < 0.05). After treatment, the intervention group had significantly better peak VO2, VO2max, VCO2max, VEmax, and METsmax than the control group (P < 0.05). After treatment, the scores of physical functioning (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT), social functioning (SF), role emotional (RE), and mental health (MH) in both groups increased significantly compared to pre-treatment (P < 0.05), and the intervention group had higher scores in PF, BP, GH, VT, SF, RE, and MH than the control group (P < 0.05). Conclusion: Wenyang Huoxue Formula combined with conventional cardiac rehabilitation can effectively improve the pulmonary and cardiac function and exercise capacity, as well as the quality of life in patients with stable coronary heart disease after PCI.
Keywords：stable coronary heart diseasecardiac rehabilitationWenyang Huoxue Formulacardiopulmonary exercisequality of life
Publication Date：2025-11-10
Online Publishing Date：2025-11-24(First online date of this platform, not the publication date of the document)
Pages：6( 3299-3304 )