Clinical Study on the Left Ventricular Myocardial Work in Patients with COVID-19 Infection Based on the Left Ventricle Pressure Strain Loop Technique
BAO Chengming
JIA Hui
ZHOU Yiyan
QIAN Xiaofeng
XIANG Santing
Abstract：Objective: To explore the value of left ventricular pressure-strain loop (LV-PSL) technology in the quantitative assessment of left ventricular myocardial work in patients with novel coronavirus infection. Methods: A total of 84 patients with novel coronavirus infection admitted to Lishui District People's Hospital, Nanjing from December 2022 to February 2023 were selected and divided into mild group (28 cases), common group (27 cases), severe group (16 cases), and critical group (13 cases) according to clinical classification. Another 60 healthy volunteers matched in the same period were selected as the normal control group. The LV-PSL technology was used to analyze global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE). The intra-class correlation coefficient (ICC) was used to evaluate the consistency between observers. Results: GWW in the common group, severe group, and critical group was higher than that in the normal control group and mild group (P < 0.05), while GWE was lower than that in the normal control group and mild group (P < 0.05). GWW in the severe group and critical group was higher than that in the common group (P < 0.05), but GWE was lower than that in the common group (P < 0.05). GWE in the critical group was significantly lower than that in the severe group (P < 0.05), while GWW was higher than that in the severe group (P < 0.05). There was no statistically significant difference in GLS between the mild group and the normal control group (P > 0.05), but GLS in the severe group and critical group was lower than that in the normal control group (P < 0.05). Conclusion: LV-PSL technology can quantitatively assess left ventricular myocardial work, and detect early left ventricular myocardial damage in patients with novel coronavirus infection, providing a basis for further clinical diagnosis and treatment.
Keywords：COVID-19myocardial workleft ventricle pressure strain loop technique
Publication Date：2025-10-10
Online Publishing Date：2025-10-24(First online date of this platform, not the publication date of the document)
Pages：4( 2979-2982 )