The Prescription Rules and Academic Thoughts of Professor Zhou Hua in the Treatment of Coronary Heart Disease Based on Data Mining
WANG Xinting
LIU Qian
CHENG Peipei
YANG Tianshu
HU Yiran
DAI Enrui
SHA Wanjing
RONG Jingfeng
QU Huiyan
ZHOU Hua
Abstract：Objective:To analyze the prescription and medication rules of Professor Zhou Hua,a famous Traditional Chinese Medicine(TCM)doctor in Shanghai,for the treatment of coronary heart disease(CHD)by data mining method,to explore the academic ideas,and provide reference for the clinical application of TCM for CHD.Methods:The medical records of Professor Zhou Hua's diagnosis and treatment of coronary heart disease from September 1,2022 to August 31,2023 were collected.The TCM inheritance computing platform V3.0 was used to analyze the categories and frequencies,properties,flavors,and meridians-tropism of TCM efficacies.The core drug combinations were analyzed using association rules and clustering algorithms.Results:A total of 105 TCM prescriptions were included,including 164 herbs,most of which were used to promote blood circulation and dissipate blood stasis,with tonifying deficiency,and calming the mind.Most of the four qi prescriptions were warm drugs,and most of the five tastes were bitter and sweet.The meridians of traditional Chinese medicine mostly retated the liver,heart,lung,and spleen meridians.The network topology of drug association rules mainly included Chuanxiong,Danshen,Xiebai,Gualoupi,Zhenzhumu,Yuanzhi,Maidong,and Xiakucao.Four core drug combinations were extracted by cluster analysis.Conclusion:This study analyzes Professor Zhou Hua's prescription and medication rules for the treatment of CHD,reflecting the academic ideas of"treating both symptoms and psychological"and"treating both heart and kidney".This study provides some ideas for the clinical application of TCM for CHD.
Keywords：coronary heart diseaseZhou Huadata miningprescription regularitytreating both symptoms and psychologicaltreating both heart and kidneytreating both hearts
Publication Date：2025-08-10
Online Publishing Date：2025-08-20(First online date of this platform, not the publication date of the document)
Pages：8( 2270-2277 )