Current Analysis of Guizhi Gancao Longgu Muli Decoction and Its Modified Formulas for the Treatment of Cardiovascular Diseases Based on the Oxford Evidence Levels
ZHANG Xiang
YU Qiuting
FAN Mingzhe
CHEN Xinlin
Abstract：Guizhi Gansao Longgu Muli Tang has the effect of warming and promoting heart yang, and calming the mind. It is used to treat conditions caused by deficiency of heart yang and floating of the spirit. It has a wide range of clinical applications and has proven efficacy for various cardiovascular diseases. By using the China National Knowledge Infrastructure (CNKI) database, we retrieved clinical studies on Guizhi Gansao Longgu Muli Tang and its modified formulas in the treatment of cardiovascular diseases, collecting a total of 96 papers related to five types of cardiovascular diseases. Using the Oxford Evidence Levels system in evidence-based medicine, we classified and evaluated the literature, analyzing the corresponding levels for each disease. The five disease categories were divided into three levels, with the main application direction being ventricular premature contractions, secondary application directions being insomnia, and other application directions including atrial premature contractions, atrial fibrillation, and heart failure. This review summarizes the current status of each application direction and the research directions for different diseases.
Keywords：cardiovascular diseasesGuizhi Gancao Longgu Muli Decoctionclinical studythe Oxford evidence levels
Publication Date：2025-07-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 2146-2151 )