Distribution and Change of TCM Syndrome before and after PCI and Risk Factors for Restenosis in Patients with Unstable Angina
AN yan
BIAN Xiaoyuan
WANG Shiqin
Abstract：Objective: To explore the distribution and change rules of traditional Chinese medicine (TCM) syndromes before and after percutaneous coronary intervention (PCI) in patients with unstable angina pectoris (UAP), as well as the risk factors for in-stent restenosis (ISR). Methods: A total of 143 UAP patients who underwent PCI and had a one-year follow-up coronary angiography at our hospital between March 2021 and March 2023 were selected. The TCM syndromes before and after PCI were analyzed, and general data of patients with and without ISR were collected and compared. Logistic regression analysis was used to identify independent risk factors for ISR after PCI, and a structural equation model was constructed. Results: Before PCI, the main syndrome was qi deficiency and blood stasis, with accompanying syndromes of qi-yang deficiency, phlegm-dampness, and heat syndrome. After PCI, the main syndrome was qi-yang deficiency, with accompanying syndromes of blood stasis, phlegm-dampness, and heat syndrome. Logistic analysis showed that stent length > 20 mm, irregular use of antiplatelet drugs, stent diameter < 3 mm, and history of hypertension were independent risk factors for ISR (P < 0.05). The multivariate model composed of these factors showed good performance in assessing the risk of ISR after PCI. The structural equation model demonstrated that the model could well reflect the relationship between influencing factors and the occurrence of ISR, with all regression paths having statistical significance (P < 0.001). Conclusion: Stent length > 20 mm, irregular use of antiplatelet drugs, stent diameter < 3 mm, and history of hypertension are all risk factors for ISR in UAP patients after PCI.
Keywords：unstable angina pectoristraditional Chinese medicine syndromepercutaneous coronary interventionin-stent restenosis
Publication Date：2025-06-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 1857-1864 )