Exploring the Mechanism of Action of Chinese Medicine in Regulating Cardiac Vascular Endothelial Function Based on NRG-1 Autocrine
GE Zhao
YANG Zhihua
REN Silin
WANG Xianliang
Abstract：NRG-1 autocrine is closely related to cardiac vascular endothelial function. It plays an important role in regulating cardiac vascular endothelial function by modulating inflammatory responses, oxidative stress, cell apoptosis, autophagy, and angiogenesis. In recent years, studies have found that traditional Chinese medicine has advantages of multiple components, multiple pathways, and multiple targets in regulating cardiac vascular endothelial function. Based on this, this study systematically reviews the relationship between NRG-1 autocrine and cardiac vascular endothelial function, as well as the research progress of traditional Chinese medicine in regulating NRG-1 autocrine to protect cardiac vascular endothelial function, aiming to provide references for clinical practice.
Keywords：cardiovascular diseasestraditional Chinese medicineneuregulin-1/epidermal growth factor receptor signaling pathwayendothelial functionreview
Publication Date：2025-06-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1835-1838 )