Clinical Study of Xiongbi No.3 Formula for the Treatment of Angina Pectoris after Percutaneous Coronary Intervention
ZHANG Ting
LI Ying
PEI Wen
ZHU Hui
LI Wenbin
Abstract：Objective: To observe the clinical efficacy of Xionobi No. 3 Formula in patients with post-PCI angina pectoris of Qi deficiency and blood stasis syndrome. Methods: A total of 102 patients were randomly assigned to treatment group and control group using SPSS 20.0 software, with 51 cases in each group. During the study, 2 patients dropped out from each group, leaving 49 patients in each group. All patients received standard internal medical treatment according to guidelines, while the treatment group also received Xionobi No. 3 Formula for a course of 3 months. The changes in TCM syndrome scores, efficacy on angina pectoris and electrocardiogram, Seattle Angina Questionnaire (SAQ) scores, and serum levels of nitric oxide (NO) and endothelin-1 (ET-1) were observed and compared before and after treatment. Results: The total effective rate of TCM syndrome in the treatment group was 91.84%, while that in the control group was 69.39%, with significant statistical difference (P < 0.005). The total effective rate of angina pectoris in the treatment group was 93.88%, compared to 69.39% in the control group, showing significant statistical difference (P = 0.002). After treatment, both groups showed decreased TCM syndrome scores and serum ET-1 levels compared to before treatment, with the treatment group showing lower values than the control group (P < 0.05). After treatment, both groups showed increased SAQ scores and serum NO levels compared to before treatment, with the treatment group showing higher values than the control group (P < 0.05). Conclusion: Xionobi No. 3 Formula treats post-PCI angina pectoris by focusing on the spleen, which can improve patients' quality of life and physical function, and enhance vascular endothelial function.
Keywords：coronary heart diseaseangina pectorispercutaneous coronary interventionQi deficiency and blood stasis syndromeXiongbi No.3 formulaSeattle Angina Questionnairevascular endothelial function
Publication Date：2025-05-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1533-1537 )