Comparative Study of PRECISE-DAPT,SYNTAX and ATRIA Scores in Predicting All-cause Death in NSTEMI Patients

LI Minglan; CHEN Hairong; PAN Biyun

doi:10.12102/j.issn.1672-1349.2025.09.014

Abstract：Objective: To explore the predictive value of the PRECISE-DAPT score, SYNTAX score, and atrial fibrillation thromboembolism risk (ATRIA) score for in-hospital all-cause mortality in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Methods: This study was a retrospective, single-center, cross-sectional, observational study. A total of 343 patients diagnosed with NSTEMI and treated in the intensive care unit of our hospital from January 2022 to December 2022 were selected as the study subjects. According to their in-hospital mortality status, they were divided into the death group (31 cases) and the survival group (312 cases). Data on general information, laboratory indicators, and risk scores (SYNTAX, PRECISE-DAPT, and ATRIA scores) were collected. Multivariate logistic regression analysis was used to identify independent predictors of all-cause mortality in NSTEMI patients. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive performance of the PRECISE-DAPT score and SYNTAX score for all-cause mortality in NSTEMI patients. Results: There were statistically significant differences between the two groups in age, proportion of diabetes mellitus, hemoglobin levels, estimated glomerular filtration rate (eGFR), high-sensitivity troponin I (hs-cTnT-I) levels, SYNTAX score, PRECISE-DAPT score, and ATRIA score (P < 0.05). Multivariate logistic regression analysis showed that the PRECISE-DAPT score and SYNTAX score were independent predictors of in-hospital all-cause mortality in NSTEMI patients. ROC curve analysis showed that the PRECISE-DAPT score had a higher area under the curve (AUC = 0.755, 95% CI [0.659, 0.851], P < 0.001) for predicting in-hospital mortality compared to the SYNTAX score (AUC = 0.717, 95% CI [0.606, 0.829], P < 0.001). Conclusion: The PRECISE-DAPT score and SYNTAX score are independent predictors of in-hospital all-cause mortality in NSTEMI patients, and the PRECISE-DAPT score has better predictive ability for all-cause mortality in NSTEMI patients than the SYNTAX score.